JP6933858B2 - 類縁アレルを検出可能な多重核酸アッセイ法およびその試薬 - Google Patents

類縁アレルを検出可能な多重核酸アッセイ法およびその試薬 Download PDF

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JP6933858B2
JP6933858B2 JP2018552172A JP2018552172A JP6933858B2 JP 6933858 B2 JP6933858 B2 JP 6933858B2 JP 2018552172 A JP2018552172 A JP 2018552172A JP 2018552172 A JP2018552172 A JP 2018552172A JP 6933858 B2 JP6933858 B2 JP 6933858B2
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primer
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dna
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JP2019510501A (ja
JP2019510501A5 (OSRAM
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エー．イー． マラス，サルヴァトーレ
エー．イー． マラス，サルヴァトーレ
ヴァーガス−ゴールド，ダイアナ
ティアギ，サンジェイ
ラッセル クレイマー，フレッド
ラッセル クレイマー，フレッド
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Rutgers State University of New Jersey
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
    • C12Q2537/143—Multiplexing, i.e. use of multiple primers or probes in a single reaction, usually for simultaneously analyse of multiple analysis
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

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JP2018552172A 2016-04-07 2017-04-05 類縁アレルを検出可能な多重核酸アッセイ法およびその試薬 Active JP6933858B2 (ja)

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Application Number Priority Date Filing Date Title
US201662319332P 2016-04-07 2016-04-07
US62/319,332 2016-04-07
PCT/US2017/026088 WO2017176852A1 (en) 2016-04-07 2017-04-05 Multiplex nucleic acid assay methods capable of detecting closely related alleles, and reagents therefor

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JP2019510501A JP2019510501A (ja) 2019-04-18
JP2019510501A5 JP2019510501A5 (OSRAM) 2020-07-09
JP6933858B2 true JP6933858B2 (ja) 2021-09-08

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US (1) US11542547B2 (OSRAM)
EP (1) EP3440226B1 (OSRAM)
JP (1) JP6933858B2 (OSRAM)
CN (1) CN109312398B (OSRAM)
AU (1) AU2017246663B2 (OSRAM)
NZ (1) NZ748011A (OSRAM)
SG (1) SG11201808740TA (OSRAM)
WO (1) WO2017176852A1 (OSRAM)
ZA (1) ZA201807405B (OSRAM)

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US12152275B2 (en) 2010-05-18 2024-11-26 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US11322224B2 (en) 2010-05-18 2022-05-03 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US9677118B2 (en) 2014-04-21 2017-06-13 Natera, Inc. Methods for simultaneous amplification of target loci
US12221653B2 (en) 2010-05-18 2025-02-11 Natera, Inc. Methods for simultaneous amplification of target loci
US10316362B2 (en) 2010-05-18 2019-06-11 Natera, Inc. Methods for simultaneous amplification of target loci
US11939634B2 (en) 2010-05-18 2024-03-26 Natera, Inc. Methods for simultaneous amplification of target loci
US20190010543A1 (en) 2010-05-18 2019-01-10 Natera, Inc. Methods for simultaneous amplification of target loci
JP6153874B2 (ja) 2011-02-09 2017-06-28 ナテラ， インコーポレイテッド 非侵襲的出生前倍数性呼び出しのための方法
US20140100126A1 (en) 2012-08-17 2014-04-10 Natera, Inc. Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data
US20180173845A1 (en) 2014-06-05 2018-06-21 Natera, Inc. Systems and Methods for Detection of Aneuploidy
EP3294906B1 (en) 2015-05-11 2024-07-10 Natera, Inc. Methods for determining ploidy
WO2017181202A2 (en) 2016-04-15 2017-10-19 Natera, Inc. Methods for lung cancer detection
GB201618485D0 (en) 2016-11-02 2016-12-14 Ucl Business Plc Method of detecting tumour recurrence
WO2019118926A1 (en) 2017-12-14 2019-06-20 Tai Diagnostics, Inc. Assessing graft suitability for transplantation
EP3737773B1 (en) * 2018-01-12 2023-04-12 Natera, Inc. Novel primers and uses thereof
CA3090426A1 (en) 2018-04-14 2019-10-17 Natera, Inc. Methods for cancer detection and monitoring by means of personalized detection of circulating tumor dna
US12234509B2 (en) 2018-07-03 2025-02-25 Natera, Inc. Methods for detection of donor-derived cell-free DNA
EP3856931B1 (en) * 2018-09-25 2023-10-11 Co-Diagnostics, Inc. Allele-specific design of cooperative primers for improved nucleic acid variant genotyping
CN110964814B (zh) * 2018-09-30 2024-05-03 迈克生物股份有限公司 用于核酸序列变异检测的引物、组合物及方法
CN111349691B (zh) * 2018-12-21 2023-10-20 迈克生物股份有限公司 Egfr基因缺失突变检测用组合物、试剂盒及检测方法
CN110592215A (zh) * 2019-09-27 2019-12-20 迈克生物股份有限公司 检测核酸序列的组合物及检测方法
CN110541033B (zh) * 2019-09-27 2023-11-14 迈克生物股份有限公司 Egfr基因突变检测用组合物及检测方法
US20220333183A1 (en) * 2019-10-02 2022-10-20 Rutgers, The State University Of New Jersey Assay methods and kits for detecting rare sequence variants
CN112824535B (zh) * 2019-11-21 2023-07-04 迈克生物股份有限公司 基因突变多重检测用引物组合物及其试剂盒
CN116121358B (zh) * 2022-11-11 2024-07-23 重庆浦济生命科技有限公司 用于精神药物基因检测的组合物、试剂盒及使用方法
EP4488384A1 (en) * 2023-07-05 2025-01-08 Infiniplex Ltd. Primers for selective amplification of rare target sequences

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Publication number Priority date Publication date Assignee Title
US7198897B2 (en) 2001-12-19 2007-04-03 Brandeis University Late-PCR
US20060141518A1 (en) * 2004-03-24 2006-06-29 Lao Kai Q Detection of gene expression
AU2007333040B2 (en) 2006-12-13 2013-02-07 Luminex Corporation Systems and methods for multiplex analysis of PCR in real time
CN110195097B (zh) * 2013-02-07 2025-01-24 新泽西鲁特格斯州立大学 高度选择性核酸扩增引物
US10480035B2 (en) 2013-09-13 2019-11-19 Rutgers, The State University Of New Jersey Multiplex diagnostic assays for Lyme disease and other tick-borne diseases
GB201409786D0 (en) 2014-06-02 2014-07-16 Primer Design Ltd Nucleic acid amplification system
WO2016014921A1 (en) 2014-07-24 2016-01-28 Brandies University Linear-expo-linear pcr (lel-pcr)

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ZA201807405B (en) 2021-04-28
CA3020165A1 (en) 2017-10-12
AU2017246663A1 (en) 2018-11-22
EP3440226B1 (en) 2021-02-17
CN109312398B (zh) 2022-05-31
US20190225999A1 (en) 2019-07-25
JP2019510501A (ja) 2019-04-18
EP3440226A1 (en) 2019-02-13
SG11201808740TA (en) 2018-11-29
AU2017246663B2 (en) 2022-09-01
CN109312398A (zh) 2019-02-05
US11542547B2 (en) 2023-01-03
WO2017176852A1 (en) 2017-10-12
EP3440226A4 (en) 2019-11-13
NZ748011A (en) 2025-05-02

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