JP6914336B2 - 進行したｈｅｒ２発現がんの治療 - Google Patents

進行したｈｅｒ２発現がんの治療 Download PDF

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Publication number
JP6914336B2
JP6914336B2 JP2019534843A JP2019534843A JP6914336B2 JP 6914336 B2 JP6914336 B2 JP 6914336B2 JP 2019534843 A JP2019534843 A JP 2019534843A JP 2019534843 A JP2019534843 A JP 2019534843A JP 6914336 B2 JP6914336 B2 JP 6914336B2
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her2
trastuzumab
cancer
pertuzumab
pharmaceutical composition
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Japanese (ja)
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JP2020514281A (ja
JP2020514281A5 (cg-RX-API-DMAC10.html
Inventor
メアリー ビーティー，
メアリー ビーティー，
メリッサ ブラマー，
メリッサ ブラマー，
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Genentech Inc
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Genentech Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507—Comprising a combination of two or more separate antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP2019534843A 2016-12-28 2017-12-14 進行したｈｅｒ２発現がんの治療 Active JP6914336B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021115575A JP7234303B2 (ja) 2016-12-28 2021-07-13 進行したｈｅｒ２発現がんの治療

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201662439815P 2016-12-28 2016-12-28
US62/439,815 2016-12-28
US201762457672P 2017-02-10 2017-02-10
US62/457,672 2017-02-10
US201762519599P 2017-06-14 2017-06-14
US62/519,599 2017-06-14
PCT/US2017/066286 WO2018125589A1 (en) 2016-12-28 2017-12-14 Treatment of advanced her2 expressing cancer

Related Child Applications (1)

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JP2021115575A Division JP7234303B2 (ja) 2016-12-28 2021-07-13 進行したｈｅｒ２発現がんの治療

Publications (3)

Publication Number Publication Date
JP2020514281A JP2020514281A (ja) 2020-05-21
JP2020514281A5 JP2020514281A5 (cg-RX-API-DMAC10.html) 2021-07-29
JP6914336B2 true JP6914336B2 (ja) 2021-08-04

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JP2019534843A Active JP6914336B2 (ja) 2016-12-28 2017-12-14 進行したｈｅｒ２発現がんの治療
JP2021115575A Active JP7234303B2 (ja) 2016-12-28 2021-07-13 進行したｈｅｒ２発現がんの治療

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US (2) US20180221481A1 (cg-RX-API-DMAC10.html)
EP (1) EP3562844A1 (cg-RX-API-DMAC10.html)
JP (2) JP6914336B2 (cg-RX-API-DMAC10.html)
KR (1) KR102313262B1 (cg-RX-API-DMAC10.html)
CN (1) CN110099926A (cg-RX-API-DMAC10.html)
AU (2) AU2017387909A1 (cg-RX-API-DMAC10.html)
CA (1) CA3046092A1 (cg-RX-API-DMAC10.html)
IL (1) IL267675A (cg-RX-API-DMAC10.html)
MX (1) MX2019007801A (cg-RX-API-DMAC10.html)
TW (1) TW201827077A (cg-RX-API-DMAC10.html)
WO (1) WO2018125589A1 (cg-RX-API-DMAC10.html)

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EP3976098A4 (en) * 2019-05-31 2023-01-18 Zymeworks Inc. METHOD OF USING A BISPECIFIC ANTIGEN-BINDING CONSTRUCT THAT TARGETS HER2 FOR THE TREATMENT OF BILAGE DUCT CANCER
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JP2023532122A (ja) 2020-06-29 2023-07-26 ジェネンテック， インコーポレイテッド ペルツズマブにトラスツズマブを加えた固定用量配合剤
CN113999313A (zh) * 2020-07-28 2022-02-01 百奥泰生物制药股份有限公司 抗her2抗体及其应用
CN115957321A (zh) * 2023-03-03 2023-04-14 盛禾(中国)生物制药有限公司 一种抗her2抗体在制备治疗癌症的药物中的用途

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Publication number Publication date
TW201827077A (zh) 2018-08-01
IL267675A (en) 2019-08-29
WO2018125589A1 (en) 2018-07-05
US20200237910A1 (en) 2020-07-30
KR102313262B1 (ko) 2021-10-14
CA3046092A1 (en) 2018-07-05
EP3562844A1 (en) 2019-11-06
CN110099926A (zh) 2019-08-06
JP2020514281A (ja) 2020-05-21
MX2019007801A (es) 2019-10-30
JP2021178832A (ja) 2021-11-18
AU2017387909A1 (en) 2019-06-27
JP7234303B2 (ja) 2023-03-07
KR20190094228A (ko) 2019-08-12
AU2021201516A1 (en) 2021-04-01
US20180221481A1 (en) 2018-08-09

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