JP6912016B1 - Sting作動化合物 - Google Patents

Sting作動化合物 Download PDF

Info

Publication number
JP6912016B1
JP6912016B1 JP2021066254A JP2021066254A JP6912016B1 JP 6912016 B1 JP6912016 B1 JP 6912016B1 JP 2021066254 A JP2021066254 A JP 2021066254A JP 2021066254 A JP2021066254 A JP 2021066254A JP 6912016 B1 JP6912016 B1 JP 6912016B1
Authority
JP
Japan
Prior art keywords
cancer
amino
pyrazole
compound
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2021066254A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021167308A (ja
Inventor
良輔 花田
良輔 花田
雅也 小久保
雅也 小久保
昌邦 黒野
昌邦 黒野
健一 幸田
健一 幸田
洋 萩谷
洋 萩谷
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ono Pharmaceutical Co Ltd
Original Assignee
Ono Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2021503933A external-priority patent/JPWO2021205631A1/ja
Application filed by Ono Pharmaceutical Co Ltd filed Critical Ono Pharmaceutical Co Ltd
Priority to JP2021066254A priority Critical patent/JP6912016B1/ja
Priority to JP2021101469A priority patent/JP2021167320A/ja
Application granted granted Critical
Publication of JP6912016B1 publication Critical patent/JP6912016B1/ja
Publication of JP2021167308A publication Critical patent/JP2021167308A/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Landscapes

  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2021066254A 2020-04-10 2021-04-09 Sting作動化合物 Active JP6912016B1 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2021066254A JP6912016B1 (ja) 2020-04-10 2021-04-09 Sting作動化合物
JP2021101469A JP2021167320A (ja) 2020-04-10 2021-06-18 Sting作動化合物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2021503933A JPWO2021205631A1 (https=) 2020-04-10 2020-04-10
JP2021503933 2020-04-10
JP2021066254A JP6912016B1 (ja) 2020-04-10 2021-04-09 Sting作動化合物

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021101469A Division JP2021167320A (ja) 2020-04-10 2021-06-18 Sting作動化合物

Publications (2)

Publication Number Publication Date
JP6912016B1 true JP6912016B1 (ja) 2021-07-28
JP2021167308A JP2021167308A (ja) 2021-10-21

Family

ID=76969224

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021066254A Active JP6912016B1 (ja) 2020-04-10 2021-04-09 Sting作動化合物
JP2021101469A Pending JP2021167320A (ja) 2020-04-10 2021-06-18 Sting作動化合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2021101469A Pending JP2021167320A (ja) 2020-04-10 2021-06-18 Sting作動化合物

Country Status (1)

Country Link
JP (2) JP6912016B1 (https=)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002069061A (ja) * 2000-08-30 2002-03-08 Canon Inc オキサゾール化合物及びそれを用いた有機発光素子
ATE554087T1 (de) * 2004-10-29 2012-05-15 Abbott Lab Neue kinaseinhibitoren
WO2015160636A1 (en) * 2014-04-16 2015-10-22 Merck Sharp & Dohme Corp. Factor ixa inhibitors
KR102746352B1 (ko) * 2014-08-13 2024-12-24 오클랜드 유니서비시즈 리미티드 트립토판 디옥시게나제 (ido1 및 tdo)의 억제제 및 치료에서 이들의 용도
CN107849084B (zh) * 2015-12-03 2021-09-14 葛兰素史密斯克莱知识产权发展有限公司 作为sting调节剂的环状嘌呤二核苷酸
MX2020008265A (es) * 2018-02-16 2020-09-21 UCB Biopharma SRL Derivados farmaceuticos del anillo heterobiciclico 6,5.
CN120004785A (zh) * 2018-07-03 2025-05-16 诺华制药股份有限公司 用于治疗与sting活性有关的疾病的化合物和组合物

Also Published As

Publication number Publication date
JP2021167308A (ja) 2021-10-21
JP2021167320A (ja) 2021-10-21

Similar Documents

Publication Publication Date Title
JP6784348B2 (ja) Sting作動化合物
WO2024091409A1 (en) Tricyclic derivatives as kras inhibitors
JP2020515574A (ja) 免疫調節剤としての置換イソキノリン誘導体
WO2017155018A1 (ja) Trk阻害剤抵抗性の癌治療剤
WO2021206160A1 (ja) 抗体薬物複合体
WO2021205631A1 (ja) Sting作動化合物
JP6912016B1 (ja) Sting作動化合物
WO2021206158A1 (ja) がん治療方法
US20210000830A1 (en) CANCER TREATMENT METHOD USING Trk INHIBITOR AND KINASE INHIBITOR IN COMBINATION
RU2798265C2 (ru) Соединение, обладающее агонистической активностью в отношении sting
HK40053745A (en) Sting-agonist compound
HK40053745B (zh) Sting激动性化合物
WO2024053650A1 (ja) ジアシルグリセロールキナーゼαおよび/またはζ阻害活性を有する化合物およびその医薬用途

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20210412

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20210412

A871 Explanation of circumstances concerning accelerated examination

Free format text: JAPANESE INTERMEDIATE CODE: A871

Effective date: 20210412

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20210608

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20210621

R150 Certificate of patent or registration of utility model

Ref document number: 6912016

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250