JP6896856B2 - Gel deodorant - Google Patents

Description

The present invention relates to a gel-like deodorant, and more particularly to a gel-like deodorant capable of suppressing the growth and growth of bacteria and mold.

Conventionally, many deodorants and deodorants for removing bad odors generated in toilets, rooms, refrigerators, cars, etc. have been proposed. Of these, the deodorant is a type in which granules having physical or chemical adsorption performance such as activated carbon or zeolite are stored in a breathable bag, and malodor is adsorbed on the granules to remove them. Things are generally known.

However, although such a deodorant is excellent in deodorizing effect, there is a problem that it is difficult to determine the life of the deodorant, that is, the end time of the deodorant, and it is difficult to determine the replacement time of the deodorant.

To solve this problem, the applicant has previously developed and applied for a patent for a deodorant in which an adsorbent is dispersed in a gel (hereinafter referred to as "gel-like deodorant") (see Patent Document 1). ). This gel-like deodorant was very easy to use due to its high deodorizing effect and easy-to-understand end time, but there was a problem that bacteria propagated on the gel-like deodorant itself and mold grew depending on the usage environment. It was.

On the other hand, many gel preparations such as gel-like air fresheners and deodorants have been proposed so far, but it has been known that these also have a problem that bacteria and molds grow and grow. As a means for solving this problem, an antibacterial / antifungal agent such as paraben or sodium benzoate is usually added to a gel-like deodorant.

However, even if these antibacterial and antifungal agents used in conventional gel-like air fresheners and deodorants are added to gel-like deodorants, no effect is observed, or they are not effective for general gel preparations. The effect was not exhibited unless it was significantly increased from the compounding amount. Further, even if the antibacterial / antifungal effect can be confirmed immediately after the production of the gel-like deodorant, the antibacterial / antifungal effect may decrease in the latter half of the period of use of the gel-like deodorant. It was speculated that these reasons were that antibacterial and antifungal agents such as paraben and sodium benzoate were adsorbed by the adsorbent dispersed in the gel-like deodorant.

Furthermore, in recent years, from the viewpoint of safety to the human body and the environment, some countries have tightened the regulation by the positive list system for compounds that can be used as antibacterial and antifungal agents. Therefore, effective antibacterial / antifungal agents that have been conventionally available cannot be used, while the compounds listed on the positive list cannot obtain antibacterial / antifungal effects with gel-like deodorants for the above-mentioned reasons. There is a problem such as.

As described above, the gel-like deodorant cannot use the antibacterial / antifungal method used in other gel preparations, and it is necessary to suppress the growth of bacteria and the growth of mold by another method. Therefore, there has been a demand for technological development for suppressing the growth and propagation of fungi and molds of gel-like deodorants.

Japanese Unexamined Patent Publication No. 2001-157706

The present invention has been made in view of the above-mentioned actual conditions, and in a deodorant in which an adsorbent is dispersed in a gel, bacterial growth and mold growth can be carried out from the start to the end of use without being affected by the adsorbent. The challenge is to provide technology to suppress it.

The present inventors have been diligently searching for components of gel-like deodorants that have antibacterial and antifungal effects almost unaffected by the adsorbent dispersed in the gel. As a result, specific cinnamaldehyde derivatives and / Or a cinnamcarboxylic acid derivative and 3-alkylamino-1,2-propanediol have such properties, and by blending this with a gel-like deodorant, the generation of bacteria and mold in the gel can be effectively performed. -The present invention has been completed by finding that it can suppress proliferation.

（式中、Ｒ^１は炭素数１〜３のアルコキシ基、Ｒ^２は水素原子または水酸基を示す）
及び／または
（Ｃ２）下記一般式（II）

（式中、Ｒ^３は炭素数１０〜１４のアルキル基を示す）
で表される化合物の１種または２種以上を含有することを特徴とするゲル状脱臭剤である。That is, the present invention describes the following components (A) to (D);
(A) Adsorbent (B) Gelling agent (C) Antibacterial / antifungal agent (D) Solvent-containing component (C)
(C1) The following general formula (I)

(In the formula, R ¹ represents an alkoxy group having 1 to 3 carbon atoms, and R ² represents a hydrogen atom or a hydroxyl group).
And / or (C2) The following general formula (II)

(In the formula, R ³ represents an alkyl group having 10 to 14 carbon atoms)
It is a gel-like deodorant characterized by containing one or more of the compounds represented by.

The gel-like deodorant of the present invention can prevent the growth and growth of bacteria and mold from the start to the end of use, suppress the functional deterioration of the adsorbent, and maintain the deodorizing effect.

The gel-like deodorant of the present invention contains the components (A) adsorbent, (B) gelling agent, (C) antibacterial / antifungal agent, and (D) solvent.

Examples of the component (A) adsorbent include a conventionally known activated carbon such as coconut shell activated carbon, a carbon-based adsorbent such as charcoal such as Bincho charcoal; and a silica-based adsorbent such as zeolite, silica gel, and layered zinc aluminosilicate. One or more of these can be used. Of these, a carbon-based adsorbent is preferable from the viewpoint of maintaining the deodorizing effect, gel stability, and the like, and it is particularly preferable to use (a1) activated carbon and (a2) Bincho charcoal in combination. Further, it is desirable to use an adsorbent having a particle size of 100 mesh or more from the viewpoint of gel formability and adsorption ability.

The content of the (A) adsorbent in the gel-like deodorant of the present invention is not particularly limited, but is usually 0.1 to 10% by mass (hereinafter, simply indicated by "%"), preferably 0. It is 5 to 5%. When (a1) activated carbon and (a2) Bincho charcoal are used in combination as the (A) adsorbent, the compounding mass ratio ((a1) :( a2)) is preferably 2: 1 to 1: 1. More preferably, it is 3: 2 to 1: 1.

As the component (B) gelling agent, conventionally known substances such as carrageenan, gellan gum, agar, gelatin, guar gum, pectin, locust bean gum, xanthan gum, sodium alginate, and cellulose derivatives can be used, and one or more of these can be used. Can be used. Examples of the cellulose derivative include hydroxypropylmethyl cellulose, hydroxyethyl cellulose, carboxymethyl cellulose and the like, and hydroxypropylmethyl cellulose is particularly preferable. Of these, (b1) carrageenan and (b2) hydroxypropyl methylcellulose are preferable, and it is preferable to use them in combination from the viewpoint of gel stability and the like.

The content of the component (B) gelling agent in the gel-like deodorant is not particularly limited, but is usually 0.1 to 10%, preferably 0.5 to 5%. When (b1) carrageenan and (b2) hydroxypropyl methylcellulose are used in combination as the component (B), the compounding mass ratio ((b1) :( b2)) is 10: 1 to 1: 1 and further 7: 1 to 2: It is preferable to combine at 1.

Ingredients (C) As an antibacterial / antifungal agent, (C1) a cinnamaldehyde derivative and / or a cinnamcarboxylic acid derivative represented by the following general formula (I), and / or (C2) the following general formula (II). It contains one or more of the represented 3-alkylamino-1,2-propanediols.

（式中、Ｒ^１は炭素数１〜３のアルコキシ基、Ｒ^２は水素原子または水酸基を示す）

(In the formula, R ¹ represents an alkoxy group having 1 to 3 carbon atoms, and R ² represents a hydrogen atom or a hydroxyl group).

（式中、Ｒ^３は炭素数１０〜１４のアルキル基を示す）

(In the formula, R ³ represents an alkyl group having 10 to 14 carbon atoms)

Specific examples of the cinnamaldehyde derivative represented by the above formula (I) include o-methoxycinnamaldehyde, m-methoxycinnamaldehyde, p-methoxycinnamaldehyde, o-ethoxycinnamaldehyde, m-ethoxycinnamaldehyde, and p. Examples thereof include −ethoxycinnamaldehyde, o-propoxycinnamaldehyde, m-propoxycinnamaldehyde, and p-propoxycinnamaldehyde. Among these, methoxycinnamaldehyde (o-methoxycinnamaldehyde, m-methoxycinnamaldehyde, p-methoxycinnamaldehyde) is preferable, and (c1) o-methoxycinnamaldehyde is particularly preferable from the viewpoint of antibacterial / antifungal effect and deodorizing effect. Mualdehyde is preferred. As o-methoxycinnamaldehyde, those commercially available from Wako Pure Chemical Industries, Ltd. can be used. In addition, o-methoxycinnamaldehyde is also abundantly contained in cinnamon bark, and cinnamon essential oil or an extract can be used.

On the other hand, as the cinnamcarboxylic acid derivative represented by the formula (I), specifically, o-methoxysilicic acid, m-methoxysilicic acid, p-methoxysilicic acid, o-ethoxysilicic acid, m-ethoxykeihi Examples thereof include acids, p-ethoxysilicic acid, o-propoxysilicic acid, m-propoxysilicic acid and p-propoxysilicic acid.

The content of the component (C1) in the gel-like deodorant is not particularly limited, but is usually 0.01 to 10%, preferably 0.025 to 2%.

Further, as the 3-alkylamino-1,2-propanediol represented by the formula (II), specifically, 3-decylamino-1,2-propanediol and 3-undecylamino-1,2-propane. Examples thereof include diol, 3-dodecylamino-1,2-propanediol, 3-tridecylamino-1,2-propanediol, and 3-tetradecylamino-1,2-propanediol. Among these, (c2) 3-dodecylamino-1,2-propanediol is preferable from the viewpoint of antibacterial / antifungal effect, deodorizing effect and the like.

The content of the component (C2) in the gel-like deodorant is not particularly limited, but is usually 0.01 to 2%, preferably 0.01 to 0.5%. Further, it is preferable to use (c1) and (c2) in combination from the viewpoint of suppressing the growth of bacteria and molds, maintaining the deodorizing effect, and the like, and the compounding mass ratio ((c1) :( c2)) in that case is 20: 1. It is preferably in the range of ~ 1: 5, and more preferably in the range of 10: 1 to 1: 3.

By emulsifying and dispersing the component (C1) and / or the component (C2) in a surfactant in advance, the gel-like deodorant of the present invention can be easily prepared. Examples of the surfactant include polyoxyethylene alkyl ether, polyoxyethylene alkyl phenyl ether, polyoxyethylene styrylphenyl ether, polyoxyethylene alkyl amino ether, polyethylene glycol fatty acid ester, polyoxyethylene polyoxypropylene glycol, and sorbitan fatty acid ester. Polyoxyethylene sorbitan fatty acid ester, polyoxyethylene hydrogenated castor oil ether, sodium alkylsulfate, sodium polyoxyethylene alkyl ether sulfate, sodium polyoxyethylene alkylphenyl ether sulfate, sodium dialkylsulfonate, polyoxyethylene alkyl ether phosphoric acid, poly Oxyethylene alkyl phenyl ether phosphoric acid, palm oil fatty acid methyl taurine sodium (N-cocoyl-N-methyl taurine sodium), lauryl sulfate triethanolamine, lauryl sulfate sodium, lauroyl sarcosin sodium, lauroyl methyl β-alanine sodium solution, lauroyl methyl Examples thereof include sodium taurine, 2-alkyl-N-carboxymethyl-N-hydroxyethyl imidazolinium betaine, alkyldiaminoethylglycine hydrochloride solution, lauryldimethylaminoacetic acid betaine and the like. Further, since (c2) 3-dodecylamino-1,2-propanediol can also be used as a surfactant, it is also possible to use (c1) and (c2) in combination to prepare an emulsified dispersed state. .. Since preparations containing o-methoxycinnamaldehyde and 3-dodecylamino-1,2-propanediol as surfactants, such as "GL-200" manufactured by BJ BIOCHEM, are also commercially available, even if they are used. Good.

In the present invention, it is preferable to further use (c3) disodium ethylenediaminetetraacetate (EDTA) as the component (C) from the viewpoint of suppressing the growth of bacteria and molds and maintaining the deodorizing effect for a long period of time. The content of EDTA is not particularly limited, but is usually 0.001 to 1%, preferably 0.01 to 0.1%. The content of the component (C) antibacterial / antifungal agent in the gel-like deodorant is not particularly limited, but is usually 0.02 to 10%, preferably 0.04 to 3%. In the present invention, as the component (C), components other than (c1), (c2) and (c3) can be used, but it is preferable to use only (c1), (c2) and (c3).

Examples of the component (D) solvent include water, ethanol, alcohols such as propanols, glycols such as propylene glycol and ethylene glycol, and the like. In addition, antibacterial and antifungal agents such as 3-methoxybutanol, 1-methoxy-2-butanol, 1-methoxy-2-propanol, 3-methoxy-3-methyl-1-butanol, 3-methoxy-3-methylbutyl acetate, etc. A solvent having an effect can also be used. Of these, (d1) water and (d2) ethanol are preferably used, and particularly preferably a combination thereof, from the viewpoints of ease of gel preparation, gel stability, clarity of the end point of use, and the like.

The content of the component (D) in the gel-like deodorant is not particularly limited, but is usually 80 to 98%, preferably 85 to 95%. Generally, in a gel-like deodorant, when the water content is high, bacteria and molds are likely to be generated. However, in the present invention, the water content (d1) may be set to, for example, 85% or more, further 87% or more. , It is possible to suppress the growth and growth of bacteria and mold. The upper limit is, for example, 95% or less, preferably 90% or less. The content of (d2) ethanol in combination is preferably 0.1 to 15%, more preferably 1 to 10%. These compounding mass ratios ((d1) :( d2)) are preferably 90: 1 to 10: 1, more preferably 80: 1 to 10: 1. In the present invention, the growth and growth of bacteria and fungi can be suppressed during the period of use without using the solvent having the antibacterial and antifungal effects.

Further, various additives can be added to the gel-like deodorant of the present invention to the extent that it does not affect gel formation. Examples of the additive include an alkali metal salt such as sodium chloride as a gel strengthening agent and an alkaline earth metal salt such as calcium chloride. Further, deodorant components such as surfactants, preservatives, ultraviolet absorbers, organic acids, pigments, fragrances, copper sulfate and plant extracts can also be added.

The gel-like deodorant of the present invention can be produced by mixing the above components (A) to (D) and any additive added as needed according to a known method. For example, (B) a gelling agent, (C) an antibacterial / antifungal agent and a surfactant are added to a solvent such as (D) water, heated and stirred, and then (A) a small amount of a powdery adsorbent is added. It can be produced by adding a dispersion in the water of the above, further stirring to obtain a uniform solution, and finally pouring this solution into a container, cooling and gelling.

The following composition can be exemplified as a preferable embodiment of the gel-like deodorant of the present invention.
(A) Adsorbent (a1) Activated carbon 0.3 to 3%
(A2) Bincho charcoal 0.2-2%
(A1): (a2) = 3: 2 to 1: 1
(B) Gelling agent (b1) Carrageenan 0.4-5%
(B2) Hydroxypropyl Methyl Cellulose 0.1 to 2%
(B1): (b2) = 10: 1 to 1: 1
(C) Antibacterial / antifungal agent (c1) o-methoxycinnamaldehyde 0.025 to 2%
(C2) 3-dodecylamino-1,2-propanediol 0.001-1
%
(C3) EDTA 0.01-0.1%
(C1): (c2) = 20: 1 to 1: 5
(D) Solvent (d1) Water 87-90%
(D2) Ethanol 1-10%
(D1): (d2) = 90: 1 to 10: 1

Next, the present invention will be described in more detail with reference to Examples and Test Examples, but the present invention is not limited to these Examples.

Example 1
A gel deodorant was prepared by the following method according to the composition shown in Table 1.

※１：ｏ−メトキシシンナムアルデヒド含有量１５〜４０％、３−ドデシルアミノ−
１，２−プロパンジオール含有量５〜３０％、BJ BIOCHEM社製
※２：GT-C12WBB097、Ewoo chem社製

* 1: O-methoxycinnamaldehyde content 15-40%, 3-dodecylamino-
1,2-Propanediol content 5-30%, manufactured by BJ BIOCHEM * 2: GT-C12WBB097, manufactured by Ewoo chem

[Manufacturing method]
Ingredients 1 to 11 were dispersed in components 12 to 13, heated to 70 ° C., stirred, poured into a glass beaker, and allowed to stand at room temperature for gelation to obtain a gel-like deodorant.

Trial example 1
Each gel-like deodorant prepared in Example 1 was heated again to 80 ° C. to dissolve it, and then 30 g of each was poured into a sterilized petri dish to cool and solidify. A sterilized circular piece of paper having a diameter of 10 mm was inoculated with 50 μl each of a suspension of the following three types of bacteria or molds, and then the piece of paper was brought into contact with the gel in a petri dish and allowed to stand. One, two or three days after standing, each piece of paper was collected and suspended in 10 ml of sterilized saline. After inoculating 100 μl of this physiological saline into the TSA medium for the fungus and the SDA medium for the mold, the fungus was cultured in the incubator for 48 hours and the mold for 72 hours, and the growth status of the fungus and the mold was visually observed. Evaluated according to criteria. The results are shown in Table 2.

[Test bacteria / mold]
Bacteria: Bacterial bacterium solution in which the following three types of bacteria are mixed at a ratio of 1: 1: 1 Pseudomonas aeruginosa (KCTC2513)
Staphylococcus aureus (KCTC3)
881)
E. coli (Escherich i a Coli, KCTC 2571 )
Mold 1: Candida albicans, CKTC 7
965)
Mold 2: Black mold (Aspergillus Niger, KCTC 6317)

[Evaluation criteria]
+: Growth of fungi and molds is observed.
±: Very slight growth of fungi and molds is observed.
-: No growth of fungi or molds is observed.

In Comparative Products 1 to 3, growth of both fungi and mold was observed, whereas in Product 1 of the present invention, the growth of fungi and mold could be completely prevented.

Trial example 2
Each gel-like deodorant prepared in Example 1 was dried until the weight was halved to prepare a gel-like deodorant in a state in the latter half of the period of use. The gel was cut with a sterilized blade and placed on a sterilized petri dish. A sterilized circular piece of paper having a diameter of 10 mm was inoculated with 50 μl of a suspension of the same three types of fungi or molds as in Test Example 1, and then the piece of paper was brought into contact with the gel in a petri dish and allowed to stand. One, two or three days after standing, each piece of paper was collected and suspended in 10 ml of sterilized saline. After inoculating 100 μl of this physiological saline into the TSA medium for the fungus and the SDA medium for the mold, the fungus was cultured in an incubator for 48 hours and the mold for 72 hours, and the growth status of the fungus and the mold was visually observed and tested. Evaluation was performed in the same manner as in Example 1. The results are shown in Table 3.

No antibacterial or antifungal effect was observed in any of the comparative products, whereas in the product 1 of the present invention, the fungus and mold were alive at 1 day after 1 day, but after 2 days, the fungus and mold were still alive. It was confirmed that it had died and maintained its antibacterial and antifungal effects even at the end of use.

Example 2
The product 1 of the present invention obtained in Example 1 was subjected to a deodorization test by the test method shown below. The results are shown in Table 4.

[Test method]
Each of the products 1 of the present invention prepared in Example 1 was cut into cubes of 2 cm square, and this was used as a sample. One of these samples was placed in a 2 liter desiccator, and ammonia and hydrogen sulfide were injected as malodorous gases. The concentration after injecting the malodorous gas (initial concentration; A (ppm)) and the concentration after 180 minutes (B (ppm)) were measured by a detector tube, and the deodorizing rate was calculated using the following formula. The deodorant rate was also calculated for blanks in which no sample was placed in the desiccator.

Regarding the product 1 of the present invention, no decrease in the deodorizing effect was observed during the period of use.

Actual example 3
Agent example:
A gel-like deodorant was prepared in a polypropylene container according to the composition shown in Table 5. This deodorant showed good deodorizing effect, and from immediately after preparation to the end of use, it was possible to obtain a highly useful preparation without the growth of bacteria and mold on the surface of the gel.

※１：和光純薬工業株式会社製
※２：GT-C12WBB097、Ewoo chem社製

* 1: Made by Wako Pure Chemical Industries, Ltd. * 2: Made by GT-C12WBB097, Ewoo chem

The gel-like deodorant of the present invention is useful as a gel-like deodorant that can be applied under a wide range of conditions because it can maintain the deodorizing effect without the growth of bacteria or the generation of mold during the period of use.

Claims (14)

The following components (A) to ( D );
(A) Adsorbent (B) Gelling agent (C) Antibacterial / antifungal agent (D) Solvent is contained, and the component (C) is
(C1) The following general formula (I)

(In the formula, R ¹ represents an alkoxy group having 1 to 3 carbon atoms, and R ² represents a hydrogen atom or a hydroxyl group).
One or more compounds represented by (C2) The following general formula (II)

(In the formula, R ³ represents an alkyl group having 10 to 14 carbon atoms)
A gel-like deodorant containing one or more compounds represented by the above in a mass compounding ratio of 20: 1 to 1: 5. (C1) is the next component (c1);
(C1) The gel-like deodorant according to claim 1, which is o-methoxycinnamaldehyde. (C2) is the next component (c2);
(C2) The gel-like deodorant according to claim 1, which is 3-dodecylamino-1,2-propanediol. The component (C) is further the next component (c3);
(C3) EDTA
The gel-like deodorant according to any one of claims 1 to 3, which contains. The gel-like deodorant according to any one of claims 1 to 4 , wherein the component (A) adsorbent is one or more selected from the group consisting of activated carbon, charcoal, zeolite, silica gel and layered zinc aluminosilicate. Agent. The component (A) is the following components (a1) and (a2);
(A1) The gel-like deodorant according to claim 5, which contains activated carbon (a2) Bincho charcoal. The gel-like deodorant according to claim 6, which contains the components (a1) and (a2) in a mass compounding ratio of 3: 2 to 1: 1. Ingredient (B) The gelling agent is one or more selected from the group consisting of carrageenan, gellan gum, agar, gelatin, guar gum, pectin, locust bean gum, xanthan gum, sodium alginate and cellulose derivatives. The gel-like deodorant according to any one of 7 to 7. The component (B) is the next component (b1);
(B1) The gel-like deodorant according to claim 8, which contains carrageenan. The component (B) is further the next component (b2);
(B2) The gel-like deodorant according to claim 9, which contains hydroxypropyl methylcellulose. The gel-like deodorant according to claim 10, which contains the components (b1) and (b2) in a mass compounding ratio of 10: 1 to 1: 1. The component (D) is the following components (d1) and (d2);
(D1) The gel-like deodorant according to any one of claims 1 to 11 , which contains water (d2) ethanol. The gel-like deodorant according to claim 12, which contains the components (d1) and (d2) in a mass compounding ratio of 90: 1 to 10: 1. The gel-like deodorant according to claim 12 or 13 , wherein the content of the component (d1) is 85 to 95% by mass.