JP6863984B2 - 結晶多形とプロセス - Google Patents
結晶多形とプロセス Download PDFInfo
- Publication number
- JP6863984B2 JP6863984B2 JP2018528313A JP2018528313A JP6863984B2 JP 6863984 B2 JP6863984 B2 JP 6863984B2 JP 2018528313 A JP2018528313 A JP 2018528313A JP 2018528313 A JP2018528313 A JP 2018528313A JP 6863984 B2 JP6863984 B2 JP 6863984B2
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- JP
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- Prior art keywords
- polymorph
- pulmonary fibrosis
- treatment
- human
- effective
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4192—1,2,3-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/056—Triazole or tetrazole radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Steroid Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021062805A JP2021105029A (ja) | 2015-12-18 | 2021-04-01 | 結晶多形とプロセス |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15201223.3 | 2015-12-18 | ||
| EP15201223 | 2015-12-18 | ||
| PCT/EP2016/081432 WO2017103109A1 (en) | 2015-12-18 | 2016-12-16 | Polymorphic forms and process |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021062805A Division JP2021105029A (ja) | 2015-12-18 | 2021-04-01 | 結晶多形とプロセス |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018537469A JP2018537469A (ja) | 2018-12-20 |
| JP2018537469A5 JP2018537469A5 (https=) | 2020-03-26 |
| JP6863984B2 true JP6863984B2 (ja) | 2021-04-21 |
Family
ID=54979474
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018528313A Expired - Fee Related JP6863984B2 (ja) | 2015-12-18 | 2016-12-16 | 結晶多形とプロセス |
| JP2021062805A Pending JP2021105029A (ja) | 2015-12-18 | 2021-04-01 | 結晶多形とプロセス |
| JP2021142305A Active JP7254130B2 (ja) | 2015-12-18 | 2021-09-01 | 結晶多形および医薬組成物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021062805A Pending JP2021105029A (ja) | 2015-12-18 | 2021-04-01 | 結晶多形とプロセス |
| JP2021142305A Active JP7254130B2 (ja) | 2015-12-18 | 2021-09-01 | 結晶多形および医薬組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US10369136B2 (https=) |
| EP (2) | EP3896075A1 (https=) |
| JP (3) | JP6863984B2 (https=) |
| CN (1) | CN108602847A (https=) |
| CA (1) | CA3004632A1 (https=) |
| ES (1) | ES2925864T3 (https=) |
| WO (1) | WO2017103109A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9243021B2 (en) * | 2012-10-31 | 2016-01-26 | Galecto Biotech Ab | Galactoside inhibitor of galectins |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9027234D0 (en) | 1990-12-15 | 1991-02-06 | Harris Pharma Ltd | An inhalation device |
| DE69230613T2 (de) | 1991-07-02 | 2000-12-28 | Inhale Inc | Verfahren und vorrichtung zum abgeben von medikamenten in aerosolform |
| EP0938907B1 (en) | 1996-01-03 | 2001-12-05 | Glaxo Group Limited | Inhalation device |
| US6962151B1 (en) | 1999-11-05 | 2005-11-08 | Pari GmbH Spezialisten für effektive Inhalation | Inhalation nebulizer |
| US6482847B2 (en) * | 2000-10-03 | 2002-11-19 | Hoffmann-La Roche Inc. | Amorphous form of cell cycle inhibitor having improved solubility and bioavailability |
| DE10102846B4 (de) | 2001-01-23 | 2012-04-12 | Pari Pharma Gmbh | Aerosolgenerator |
| ATE269735T1 (de) | 2001-10-18 | 2004-07-15 | Pari Gmbh | Inhalationstherapievorrichtung |
| DE60235883D1 (de) | 2002-08-02 | 2010-05-20 | Pari Pharma Gmbh | Vorrichtung zur Erzeugung von Flüssigkeitströpfchen |
| DE10250625A1 (de) | 2002-10-30 | 2004-05-19 | Pari GmbH Spezialisten für effektive Inhalation | Inhalationstherapievorrichtung |
| DE10257381B4 (de) | 2002-12-09 | 2006-09-14 | Pari GmbH Spezialisten für effektive Inhalation | Inhalationstherapievorrichtung |
| PT104350A (pt) * | 2009-01-23 | 2010-07-23 | Hovione Farmaci Ncia S A | Processo de isolamento de tigeciclina |
| DE102009026636B4 (de) | 2009-06-02 | 2011-04-14 | Pari Pharma Gmbh | Verfahren zum Verschweißen einer Membran mit einem Träger bei der Herstellung eines Membranverneblers |
| US9243021B2 (en) | 2012-10-31 | 2016-01-26 | Galecto Biotech Ab | Galactoside inhibitor of galectins |
| CN104755088A (zh) * | 2012-10-31 | 2015-07-01 | 格莱克特生物技术公司 | 半乳凝集素-3的半乳糖苷抑制剂及其用于治疗肺纤维化的应用 |
| EP2919802A4 (en) * | 2012-11-15 | 2016-09-14 | Univ Tufts | METHOD, COMPOSITIONS AND KITS FOR TREATING, MODULATING OR PREVENTING ANGIOGENESIS OR FIBROSIS IN A PATIENT USING A GALECTINE PROTEIN HEMMER |
| WO2015155207A1 (en) * | 2014-04-08 | 2015-10-15 | Galecto Biotech Ab | Galactoside inhibitors for the treatment of alpha-synucleinopthies |
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2016
- 2016-12-16 EP EP21175042.7A patent/EP3896075A1/en not_active Withdrawn
- 2016-12-16 EP EP16809870.5A patent/EP3390423B1/en active Active
- 2016-12-16 CN CN201680071057.8A patent/CN108602847A/zh active Pending
- 2016-12-16 ES ES16809870T patent/ES2925864T3/es active Active
- 2016-12-16 US US16/062,206 patent/US10369136B2/en active Active
- 2016-12-16 WO PCT/EP2016/081432 patent/WO2017103109A1/en not_active Ceased
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| Publication number | Publication date |
|---|---|
| WO2017103109A1 (en) | 2017-06-22 |
| ES2925864T3 (es) | 2022-10-20 |
| US10307403B2 (en) | 2019-06-04 |
| EP3896075A1 (en) | 2021-10-20 |
| JP2021191777A (ja) | 2021-12-16 |
| JP7254130B2 (ja) | 2023-04-07 |
| US10799482B2 (en) | 2020-10-13 |
| JP2021105029A (ja) | 2021-07-26 |
| US20190298697A1 (en) | 2019-10-03 |
| CN108602847A (zh) | 2018-09-28 |
| US20190117627A1 (en) | 2019-04-25 |
| US10369136B2 (en) | 2019-08-06 |
| CA3004632A1 (en) | 2017-06-22 |
| EP3390423A1 (en) | 2018-10-24 |
| US20180369208A1 (en) | 2018-12-27 |
| JP2018537469A (ja) | 2018-12-20 |
| EP3390423B1 (en) | 2022-08-03 |
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