JP6840127B2 - がんの治療における抗pd−1抗体および抗m−csf抗体の併用 - Google Patents

がんの治療における抗pd−1抗体および抗m−csf抗体の併用 Download PDF

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JP6840127B2
JP6840127B2 JP2018504105A JP2018504105A JP6840127B2 JP 6840127 B2 JP6840127 B2 JP 6840127B2 JP 2018504105 A JP2018504105 A JP 2018504105A JP 2018504105 A JP2018504105 A JP 2018504105A JP 6840127 B2 JP6840127 B2 JP 6840127B2
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amino acid
seq
acid sequence
antibody molecule
cancer
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JP2018525367A (ja
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フジャエルスコッグ,マリー−ルイーズ
キャメロン,ジョン
カオ,ジュ
シポレッタ,ダニエラ
マシザック,ケンジー
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ノバルティス アーゲー
ノバルティス アーゲー
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    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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JP2018504105A 2015-07-29 2016-07-27 がんの治療における抗pd−1抗体および抗m−csf抗体の併用 Expired - Fee Related JP6840127B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562198384P 2015-07-29 2015-07-29
US62/198,384 2015-07-29
US201662352637P 2016-06-21 2016-06-21
US62/352,637 2016-06-21
PCT/IB2016/054487 WO2017017623A1 (en) 2015-07-29 2016-07-27 Combined use of anti pd-1 and anti m-csf antibodies in the treatment of cancer

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JP2018525367A JP2018525367A (ja) 2018-09-06
JP2018525367A5 JP2018525367A5 (enExample) 2019-09-05
JP6840127B2 true JP6840127B2 (ja) 2021-03-10

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JP2018504105A Expired - Fee Related JP6840127B2 (ja) 2015-07-29 2016-07-27 がんの治療における抗pd−1抗体および抗m−csf抗体の併用

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US (1) US11001628B2 (enExample)
EP (1) EP3328425B1 (enExample)
JP (1) JP6840127B2 (enExample)
KR (1) KR20180034426A (enExample)
CN (1) CN108136003A (enExample)
AU (1) AU2016300208B2 (enExample)
BR (1) BR112018000212A2 (enExample)
CA (1) CA2991857A1 (enExample)
CL (1) CL2018000222A1 (enExample)
IL (1) IL256691A (enExample)
JO (1) JO3784B1 (enExample)
MX (1) MX2018001263A (enExample)
PH (1) PH12018500174A1 (enExample)
RU (1) RU2742494C2 (enExample)
SA (1) SA518390834B1 (enExample)
TN (1) TN2017000554A1 (enExample)
TW (1) TWI735456B (enExample)
WO (1) WO2017017623A1 (enExample)

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JOP20200094A1 (ar) 2014-01-24 2017-06-16 Dana Farber Cancer Inst Inc جزيئات جسم مضاد لـ pd-1 واستخداماتها
JOP20200096A1 (ar) 2014-01-31 2017-06-16 Children’S Medical Center Corp جزيئات جسم مضاد لـ tim-3 واستخداماتها
UY36032A (es) 2014-03-14 2015-10-30 Novartis Ag Moléculas de anticuerpo que se unen a lag-3 y usos de las mismas
CN107206071A (zh) 2014-09-13 2017-09-26 诺华股份有限公司 Alk抑制剂的联合疗法
HK1250033A1 (zh) 2015-07-13 2018-11-23 Cytomx Therapeutics Inc. 抗-pd-1抗体、可活化的抗-pd-1抗体、及其使用方法
KR102220275B1 (ko) 2015-11-18 2021-02-26 머크 샤프 앤드 돔 코포레이션 Pd1 및/또는 lag3 결합제
AR112603A1 (es) 2017-07-10 2019-11-20 Lilly Co Eli Anticuerpos biespecíficos inhibidores de punto de control
US12398209B2 (en) 2018-01-22 2025-08-26 Janssen Biotech, Inc. Methods of treating cancers with antagonistic anti-PD-1 antibodies
KR102767594B1 (ko) 2018-07-12 2025-02-12 코버스 파마슈티칼스, 인크. 아데노신 경로 활성화를 갖는 암의 검출 및 치료 방법
CN112654365A (zh) 2018-07-12 2021-04-13 科尔沃斯制药股份有限公司 用于检测和治疗具有腺苷途径激活的癌症的方法
WO2020044252A1 (en) * 2018-08-31 2020-03-05 Novartis Ag Dosage regimes for anti-m-csf antibodies and uses thereof
JP2022519385A (ja) * 2019-02-12 2022-03-23 ノバルティス アーゲー Tno155及びpd-1阻害剤を含む医薬組合せ
JP2022534889A (ja) 2019-05-24 2022-08-04 ファイザー・インコーポレイテッド Cdk阻害剤を使用した組合せ療法
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JP2022537151A (ja) * 2019-06-13 2022-08-24 シートムエックス セラピューティクス,インコーポレイテッド 癌の処置のためのネオアジュバント併用療法での活性化可能抗pdl1抗体および抗ctla-4抗体の使用
WO2021226984A1 (zh) 2020-05-15 2021-11-18 三生国健药业(上海)股份有限公司 一种抗pd-1和pd-l1的四价双特异性抗体
US20220168293A1 (en) 2020-12-02 2022-06-02 Pfizer Inc. Time to resolution of axitinib-related adverse events
TW202327595A (zh) 2021-10-05 2023-07-16 美商輝瑞大藥廠 用於治療癌症之氮雜內醯胺化合物的組合
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MX2018001263A (es) 2018-04-13
RU2018106876A3 (enExample) 2020-07-17
WO2017017623A1 (en) 2017-02-02
US20180222973A1 (en) 2018-08-09
SA518390834B1 (ar) 2021-03-02
KR20180034426A (ko) 2018-04-04
AU2016300208B2 (en) 2019-08-08
US11001628B2 (en) 2021-05-11
PH12018500174A1 (en) 2018-07-30
EP3328425B1 (en) 2021-08-25
TW201718011A (zh) 2017-06-01
CL2018000222A1 (es) 2018-07-13
TN2017000554A1 (en) 2019-04-12
IL256691A (en) 2018-03-29
JP2018525367A (ja) 2018-09-06
TWI735456B (zh) 2021-08-11
EP3328425A1 (en) 2018-06-06
HK1247848A1 (zh) 2018-10-05
RU2742494C2 (ru) 2021-02-08
AU2016300208A1 (en) 2018-02-01
JO3784B1 (ar) 2021-01-31
CN108136003A (zh) 2018-06-08
BR112018000212A2 (pt) 2018-09-04
CA2991857A1 (en) 2017-02-02
RU2018106876A (ru) 2019-08-28

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