JP6839491B2 - 変形性関節症の予防および治療のためのステロイドとゾレドロン酸との併用 - Google Patents
変形性関節症の予防および治療のためのステロイドとゾレドロン酸との併用 Download PDFInfo
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- JP6839491B2 JP6839491B2 JP2015561747A JP2015561747A JP6839491B2 JP 6839491 B2 JP6839491 B2 JP 6839491B2 JP 2015561747 A JP2015561747 A JP 2015561747A JP 2015561747 A JP2015561747 A JP 2015561747A JP 6839491 B2 JP6839491 B2 JP 6839491B2
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- zoledronic acid
- pharmaceutically acceptable
- acceptable salt
- osteoarthritis
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- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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Landscapes
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- Medicinal Chemistry (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/791,685 US9012432B2 (en) | 2013-03-08 | 2013-03-08 | Co-administration of steroids and zoledronic acid to prevent and treat osteoarthritis |
| US13/791,685 | 2013-03-08 | ||
| PCT/US2014/022169 WO2014138712A1 (en) | 2013-03-08 | 2014-03-07 | Co-administration of steroids and zoledronic acid to prevent and treat osteoarthritis |
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| JP2019071500A Division JP2019104762A (ja) | 2013-03-08 | 2019-04-03 | 変形性関節症の予防および治療のためのステロイドとゾレドロン酸との併用 |
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| Publication Number | Publication Date |
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| JP2016510765A JP2016510765A (ja) | 2016-04-11 |
| JP2016510765A5 JP2016510765A5 (ko) | 2017-04-06 |
| JP6839491B2 true JP6839491B2 (ja) | 2021-03-17 |
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| US10913772B2 (en) | 2016-03-09 | 2021-02-09 | Kine Sciences Co., Ltd. | Peptide for preventing or treating inflammatory diseases and use thereof |
| US10913771B2 (en) | 2016-03-09 | 2021-02-09 | Kine Sciences Co., Ltd. | Peptide for preventing or treating inflammatory diseases and use thereof |
| US10206969B2 (en) | 2016-03-09 | 2019-02-19 | Bio Pep Co., Ltd. | Peptide for preventing or treating inflammatory diseases and use thereof |
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| JP7127616B2 (ja) | 2019-06-04 | 2022-08-30 | 横河電機株式会社 | 情報処理装置、アラーム管理システム、及びアラーム管理方法 |
| WO2021163432A1 (en) * | 2020-02-12 | 2021-08-19 | Levolta Pharmaceuticals, Inc. | Co-administration of prednisolone/methyl prednisolone and zoledronic acid to treat and prevent osteoarthritis |
| CN114028571B (zh) * | 2021-11-18 | 2023-04-28 | 中国医学科学院基础医学研究所 | 含氮双膦酸盐联合糖皮质激素在预防或治疗病毒性肺炎中的应用 |
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| KR101328470B1 (ko) * | 2005-05-25 | 2013-11-13 | 카로신 파마, 인코포레이티드 | 골관절염 치료 방법 및 조성물 |
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| US8946199B2 (en) | 2010-04-26 | 2015-02-03 | Ketan Desai | Co-administration of steroids and Zoledronic acid to prevent and treat side effects from Zoledronic acid infusion |
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| EP2964209A1 (en) | 2016-01-13 |
| CN105324113B (zh) | 2018-07-03 |
| JP2016510765A (ja) | 2016-04-11 |
| AU2014225373A1 (en) | 2015-10-22 |
| EA032067B1 (ru) | 2019-04-30 |
| EP2964209A4 (en) | 2016-08-03 |
| US9012432B2 (en) | 2015-04-21 |
| JP2019104762A (ja) | 2019-06-27 |
| ES2904365T3 (es) | 2022-04-04 |
| CA2941346C (en) | 2020-03-10 |
| CN105324113A (zh) | 2016-02-10 |
| MX2015011671A (es) | 2016-05-12 |
| BR112015021503A2 (pt) | 2018-05-15 |
| KR20150125001A (ko) | 2015-11-06 |
| EP2964209B1 (en) | 2021-10-27 |
| KR102253394B1 (ko) | 2021-05-20 |
| WO2014138712A1 (en) | 2014-09-12 |
| BR112015021503B1 (pt) | 2022-09-06 |
| EA201591638A1 (ru) | 2016-02-29 |
| CA2941346A1 (en) | 2014-09-12 |
| AU2014225373B2 (en) | 2018-07-05 |
| US20140256681A1 (en) | 2014-09-11 |
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