JP6839393B2 - 心組織を修復するための心外膜由来パラクリン因子 - Google Patents
心組織を修復するための心外膜由来パラクリン因子 Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0657—Cardiomyocytes; Heart cells
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- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
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- Cardiology (AREA)
- Cell Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
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- Developmental Biology & Embryology (AREA)
- Genetics & Genomics (AREA)
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- Wood Science & Technology (AREA)
- Inorganic Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
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- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
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Applications Claiming Priority (5)
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| US201562145480P | 2015-04-09 | 2015-04-09 | |
| US62/145,480 | 2015-04-09 | ||
| US201562196766P | 2015-07-24 | 2015-07-24 | |
| US62/196,766 | 2015-07-24 | ||
| PCT/US2016/026809 WO2016164840A1 (fr) | 2015-04-09 | 2016-04-08 | Facteurs paracrine dérivés de l'épicarde pour la réparation de tissu cardiaque |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| JP2020214644A Division JP7190711B2 (ja) | 2015-04-09 | 2020-12-24 | 心組織を修復するための心外膜由来パラクリン因子 |
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| JP2018512456A JP2018512456A (ja) | 2018-05-17 |
| JP2018512456A5 JP2018512456A5 (fr) | 2019-05-16 |
| JP6839393B2 true JP6839393B2 (ja) | 2021-03-10 |
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| JP2020214644A Active JP7190711B2 (ja) | 2015-04-09 | 2020-12-24 | 心組織を修復するための心外膜由来パラクリン因子 |
| JP2022189992A Pending JP2023018119A (ja) | 2015-04-09 | 2022-11-29 | 心組織を修復するための心外膜由来パラクリン因子 |
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| JP2020214644A Active JP7190711B2 (ja) | 2015-04-09 | 2020-12-24 | 心組織を修復するための心外膜由来パラクリン因子 |
| JP2022189992A Pending JP2023018119A (ja) | 2015-04-09 | 2022-11-29 | 心組織を修復するための心外膜由来パラクリン因子 |
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| EP (2) | EP4088733A1 (fr) |
| JP (3) | JP6839393B2 (fr) |
| CN (2) | CN108601810B (fr) |
| AU (3) | AU2016246070B2 (fr) |
| CA (1) | CA2982179A1 (fr) |
| DK (1) | DK3280429T3 (fr) |
| ES (1) | ES2927176T3 (fr) |
| HK (1) | HK1258800A1 (fr) |
| WO (1) | WO2016164840A1 (fr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4088733A1 (fr) * | 2015-04-09 | 2022-11-16 | Regencor, Inc. | Facteurs paracrines dérivés de l'épicarde pour la réparation du tissu cardiaque |
| CN108486046B (zh) * | 2018-02-09 | 2020-09-25 | 苏州大学 | 一种抗缺氧损伤的干细胞制剂及其制备方法与在制备治疗急性心梗药物中的应用 |
| WO2023183933A1 (fr) * | 2022-03-25 | 2023-09-28 | Regencor, Inc. | Utilisation de follistatine-like 1 (fstl1) dans une insuffisance cardiaque cardiométabolique |
| WO2023210713A1 (fr) * | 2022-04-27 | 2023-11-02 | 国立大学法人京都大学 | Promoteur de régénération de cellules épicardiques et procédé pour favoriser la régénération de cellules épicardiques |
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| US20040253644A1 (en) * | 1995-11-07 | 2004-12-16 | Kaneka Corporation | Rheumatoid arthritis autoantigen polypeptides |
| US7862810B2 (en) * | 2000-07-31 | 2011-01-04 | New York Medical College | Methods and compositions for the repair and/or regeneration of damaged myocardium |
| US20030199464A1 (en) * | 2002-04-23 | 2003-10-23 | Silviu Itescu | Regeneration of endogenous myocardial tissue by induction of neovascularization |
| WO2007109686A2 (fr) * | 2006-03-20 | 2007-09-27 | University Of Pittsburgh | Immunomodulation de conditions inflammatoires en utilisant la protéine 1 apparentée à la follistatine et des agents se liant à celle-ci |
| GB0611845D0 (en) * | 2006-06-15 | 2006-07-26 | Mcinerney Joseph G | The utility hydration system |
| US8329650B2 (en) * | 2007-10-19 | 2012-12-11 | Trustees Of Boston University | Method of treating ischemic injury with follistatin-like 1 polypeptide |
| US20090326053A1 (en) | 2008-05-30 | 2009-12-31 | Trustees Of Boston University | Diagnostic uses of follistatin-like 1 |
| US20100330044A1 (en) * | 2009-06-30 | 2010-12-30 | Universite Libre De Bruxelles | Mesp1 as a master regulator of multipotent cardiovascular progenitor specification and uses thereof |
| EP2494034A2 (fr) | 2009-11-01 | 2012-09-05 | Zenbio, Inc. | Cellules mésothéliales épiploïques humaines, procédés pour les isoler et leurs utilisations |
| WO2012019099A2 (fr) * | 2010-08-05 | 2012-02-09 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Protéine 1 analogue à la follistatine utilisable en tant que biomarqueur des troubles inflammatoires |
| WO2012051515A2 (fr) * | 2010-10-14 | 2012-04-19 | University Of Central Florida Research Foundation, Inc. | Cellules souches pluripotentes cardio-induites et procédés d'utilisation pour la réparation et la régénération du myocarde |
| CN102648977B (zh) * | 2011-02-25 | 2014-12-10 | 中国科学院上海生命科学研究院 | 滤泡素抑制素样蛋白1在调节钠钾atp酶活性中的用途 |
| EP4088733A1 (fr) * | 2015-04-09 | 2022-11-16 | Regencor, Inc. | Facteurs paracrines dérivés de l'épicarde pour la réparation du tissu cardiaque |
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2016
- 2016-04-08 EP EP22170285.5A patent/EP4088733A1/fr active Pending
- 2016-04-08 ES ES16777438T patent/ES2927176T3/es active Active
- 2016-04-08 US US15/565,054 patent/US10682416B2/en active Active
- 2016-04-08 CA CA2982179A patent/CA2982179A1/fr active Pending
- 2016-04-08 WO PCT/US2016/026809 patent/WO2016164840A1/fr unknown
- 2016-04-08 CN CN201680031325.3A patent/CN108601810B/zh active Active
- 2016-04-08 DK DK16777438.9T patent/DK3280429T3/da active
- 2016-04-08 AU AU2016246070A patent/AU2016246070B2/en active Active
- 2016-04-08 EP EP16777438.9A patent/EP3280429B1/fr active Active
- 2016-04-08 CN CN202210715004.2A patent/CN115417921A/zh active Pending
- 2016-04-08 JP JP2018504081A patent/JP6839393B2/ja active Active
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2019
- 2019-01-23 HK HK19101164.7A patent/HK1258800A1/zh unknown
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2020
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2022
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Also Published As
| Publication number | Publication date |
|---|---|
| DK3280429T3 (da) | 2022-08-29 |
| EP4088733A1 (fr) | 2022-11-16 |
| CN108601810A (zh) | 2018-09-28 |
| US20200345851A1 (en) | 2020-11-05 |
| CN108601810B (zh) | 2022-07-05 |
| US10682416B2 (en) | 2020-06-16 |
| ES2927176T3 (es) | 2022-11-03 |
| EP3280429A4 (fr) | 2018-12-19 |
| WO2016164840A1 (fr) | 2016-10-13 |
| AU2023214306A1 (en) | 2023-08-31 |
| AU2016246070A1 (en) | 2017-11-02 |
| AU2020204541A1 (en) | 2020-07-30 |
| JP7190711B2 (ja) | 2022-12-16 |
| US20180092980A1 (en) | 2018-04-05 |
| CA2982179A1 (fr) | 2016-10-13 |
| JP2023018119A (ja) | 2023-02-07 |
| JP2021046441A (ja) | 2021-03-25 |
| CN115417921A (zh) | 2022-12-02 |
| EP3280429A1 (fr) | 2018-02-14 |
| JP2018512456A (ja) | 2018-05-17 |
| HK1258800A1 (zh) | 2019-11-22 |
| AU2016246070B2 (en) | 2020-04-09 |
| EP3280429B1 (fr) | 2022-06-01 |
| AU2020204541B2 (en) | 2023-05-18 |
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