JP6802263B2 - Tyk2阻害剤およびその使用 - Google Patents

Tyk2阻害剤およびその使用 Download PDF

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Publication number
JP6802263B2
JP6802263B2 JP2018512319A JP2018512319A JP6802263B2 JP 6802263 B2 JP6802263 B2 JP 6802263B2 JP 2018512319 A JP2018512319 A JP 2018512319A JP 2018512319 A JP2018512319 A JP 2018512319A JP 6802263 B2 JP6802263 B2 JP 6802263B2
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compound
disorder
vii
nitrogen
compounds
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JP2018532706A (ja
JP2018532706A5 (enExample
Inventor
クレッグ イー. マッセ,
クレッグ イー. マッセ,
ジェレミー ロバート グリーンウッド,
ジェレミー ロバート グリーンウッド,
ドナ エル. ロメロ,
ドナ エル. ロメロ,
ジェラルディン シー. ハリマン,
ジェラルディン シー. ハリマン,
ロナルド ティー. ウェスター,
ロナルド ティー. ウェスター,
ミー シェリー,
ミー シェリー,
ジョシュア ジャフミル ケネディー−スミス,
ジョシュア ジャフミル ケネディー−スミス,
マルクス ダールグレン,
マルクス ダールグレン,
サヤン モンデール,
サヤン モンデール,
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ニンバス ラクシュミ, インコーポレイテッド
ニンバス ラクシュミ, インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05—Isotopically modified compounds, e.g. labelled

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2018512319A 2015-09-02 2016-09-01 Tyk2阻害剤およびその使用 Active JP6802263B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562213475P 2015-09-02 2015-09-02
US62/213,475 2015-09-02
US201562214018P 2015-09-03 2015-09-03
US62/214,018 2015-09-03
PCT/US2016/049852 WO2017040757A1 (en) 2015-09-02 2016-09-01 Tyk2 inhibitors and uses thereof

Related Child Applications (1)

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JP2019109248A Division JP2019172690A (ja) 2015-09-02 2019-06-12 Tyk2阻害剤およびその使用

Publications (3)

Publication Number Publication Date
JP2018532706A JP2018532706A (ja) 2018-11-08
JP2018532706A5 JP2018532706A5 (enExample) 2019-07-18
JP6802263B2 true JP6802263B2 (ja) 2020-12-16

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JP2018512319A Active JP6802263B2 (ja) 2015-09-02 2016-09-01 Tyk2阻害剤およびその使用
JP2019109248A Withdrawn JP2019172690A (ja) 2015-09-02 2019-06-12 Tyk2阻害剤およびその使用
JP2021093678A Pending JP2021130712A (ja) 2015-09-02 2021-06-03 Tyk2阻害剤およびその使用

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JP2019109248A Withdrawn JP2019172690A (ja) 2015-09-02 2019-06-12 Tyk2阻害剤およびその使用
JP2021093678A Pending JP2021130712A (ja) 2015-09-02 2021-06-03 Tyk2阻害剤およびその使用

Country Status (5)

Country Link
US (4) US10023571B2 (enExample)
EP (2) EP4327809A3 (enExample)
JP (3) JP6802263B2 (enExample)
TW (1) TWI707852B (enExample)
WO (1) WO2017040757A1 (enExample)

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CN114075220A (zh) * 2020-08-13 2022-02-22 广东东阳光药业有限公司 取代的杂芳基化合物及其组合物和用途
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Also Published As

Publication number Publication date
US20230074228A1 (en) 2023-03-09
JP2018532706A (ja) 2018-11-08
JP2021130712A (ja) 2021-09-09
EP4327809A3 (en) 2024-04-17
US10023571B2 (en) 2018-07-17
EP3344624A1 (en) 2018-07-11
HK1256997A1 (en) 2019-10-11
US20180354949A1 (en) 2018-12-13
EP3344624B1 (en) 2023-10-25
US20210047319A1 (en) 2021-02-18
WO2017040757A1 (en) 2017-03-09
US10781204B2 (en) 2020-09-22
US20170066763A1 (en) 2017-03-09
JP2019172690A (ja) 2019-10-10
EP4327809A2 (en) 2024-02-28
EP3344624B8 (en) 2023-11-29
TWI707852B (zh) 2020-10-21
TW201718576A (zh) 2017-06-01
EP3344624A4 (en) 2019-01-16
US11434240B2 (en) 2022-09-06

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