JP6773651B2 - ポリdnaスペーサー配列を有する配列変換およびシグナル増幅dnaならびにそれらを用いた検出方法 - Google Patents

ポリdnaスペーサー配列を有する配列変換およびシグナル増幅dnaならびにそれらを用いた検出方法 Download PDF

Info

Publication number
JP6773651B2
JP6773651B2 JP2017519832A JP2017519832A JP6773651B2 JP 6773651 B2 JP6773651 B2 JP 6773651B2 JP 2017519832 A JP2017519832 A JP 2017519832A JP 2017519832 A JP2017519832 A JP 2017519832A JP 6773651 B2 JP6773651 B2 JP 6773651B2
Authority
JP
Japan
Prior art keywords
dna
sequence
oligonucleotide
nucleic acid
signal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2017519832A
Other languages
English (en)
Japanese (ja)
Other versions
JP2017532044A5 (enExample
JP2017532044A (ja
Inventor
健 小宮
健 小宮
誠 小森
誠 小森
吉村 徹
徹 吉村
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of JP2017532044A publication Critical patent/JP2017532044A/ja
Publication of JP2017532044A5 publication Critical patent/JP2017532044A5/ja
Application granted granted Critical
Publication of JP6773651B2 publication Critical patent/JP6773651B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/682Signal amplification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Biomedical Technology (AREA)
  • Plant Pathology (AREA)
JP2017519832A 2014-10-14 2015-10-13 ポリdnaスペーサー配列を有する配列変換およびシグナル増幅dnaならびにそれらを用いた検出方法 Active JP6773651B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462063666P 2014-10-14 2014-10-14
US62/063,666 2014-10-14
US201462098066P 2014-12-30 2014-12-30
US62/098,066 2014-12-30
PCT/IB2015/002145 WO2016059474A2 (en) 2014-10-14 2015-10-13 Sequence conversion and signal amplifier dna having poly dna spacer sequences and detection methods using same

Publications (3)

Publication Number Publication Date
JP2017532044A JP2017532044A (ja) 2017-11-02
JP2017532044A5 JP2017532044A5 (enExample) 2019-01-10
JP6773651B2 true JP6773651B2 (ja) 2020-10-21

Family

ID=55655044

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2017519832A Active JP6773651B2 (ja) 2014-10-14 2015-10-13 ポリdnaスペーサー配列を有する配列変換およびシグナル増幅dnaならびにそれらを用いた検出方法
JP2017519860A Active JP6896620B2 (ja) 2014-10-14 2015-10-13 ロックされた核酸を有する配列変換およびシグナル増幅dnaならびにそれを用いた検出方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2017519860A Active JP6896620B2 (ja) 2014-10-14 2015-10-13 ロックされた核酸を有する配列変換およびシグナル増幅dnaならびにそれを用いた検出方法

Country Status (6)

Country Link
US (2) US10208333B2 (enExample)
EP (2) EP3207160B1 (enExample)
JP (2) JP6773651B2 (enExample)
CN (2) CN107109473B (enExample)
ES (2) ES2759337T3 (enExample)
WO (2) WO2016059474A2 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9845495B2 (en) 2010-12-10 2017-12-19 Abbott Laboratories Method and kit for detecting target nucleic acid
JP6739339B2 (ja) 2014-01-15 2020-08-12 アボット・ラボラトリーズAbbott Laboratories カバーされた配列変換dnaおよび検出方法
JP6773651B2 (ja) 2014-10-14 2020-10-21 アボット・ラボラトリーズAbbott Laboratories ポリdnaスペーサー配列を有する配列変換およびシグナル増幅dnaならびにそれらを用いた検出方法
ES2791280T3 (es) 2014-12-24 2020-11-03 Abbott Lab Método de detección, composición y kit basados en reacciones en cascada de ADN amplificador de señal con extensión de la diana
GB201611469D0 (en) 2016-06-30 2016-08-17 Lumiradx Tech Ltd Improvements in or relating to nucleic acid amplification processes
GB2569965A (en) 2018-01-04 2019-07-10 Lumiradx Uk Ltd Improvements in or relating to amplification of nucleic acids
WO2021252733A2 (en) * 2020-06-10 2021-12-16 Bonadea Diagnostics, Llc Sequence conversion reaction
WO2023107713A2 (en) * 2021-12-09 2023-06-15 Bonadea Diagnostics, Llc Sequence conversion reaction

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
US5455166A (en) 1991-01-31 1995-10-03 Becton, Dickinson And Company Strand displacement amplification
JPH07114718A (ja) 1993-10-18 1995-05-02 Tanashin Denki Co テープレコーダの回転ヘッド装置
US5928869A (en) 1997-05-30 1999-07-27 Becton, Dickinson And Company Detection of nucleic acids by fluorescence quenching
WO2000028082A1 (fr) 1998-11-09 2000-05-18 Eiken Kagaku Kabushiki Kaisha Procede de synthese d'acide nucleique
US6316200B1 (en) 2000-06-08 2001-11-13 Becton, Dickinson And Company Probes and methods for detection of nucleic acids
AU2001278783B2 (en) * 2000-08-23 2006-04-27 Takara Bio Inc. Method of amplifying nucleic acid
WO2004022701A2 (en) 2001-07-15 2004-03-18 Keck Graduate Institute Exponential amplification of nucleic acids using nicking agents
WO2003029459A2 (en) 2001-09-28 2003-04-10 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Micro-rna molecules
US7220544B2 (en) 2002-05-08 2007-05-22 Arkray, Inc. Method for detecting target nucleic acid
JP2006510348A (ja) 2002-07-18 2006-03-30 ザ・ボード・オブ・トラスティーズ・オブ・ザ・レランド・スタンフォード・ジュニア・ユニバーシティ 蛍光消光脱離基を用いる化学ライゲーションの検出
WO2004067764A2 (en) 2003-01-29 2004-08-12 Keck Graduate Institute Nucleic acid sequencing using nicking agents
WO2004067765A2 (en) 2003-01-29 2004-08-12 Keck Graduate Institute Organism fingerprinting using nicking agents
WO2004067726A2 (en) 2003-01-29 2004-08-12 Keck Graduate Institute Isothermal reactions for the amplification of oligonucleotides
ATE552339T1 (de) * 2003-02-21 2012-04-15 Eisai R&D Man Co Ltd Signalverstärkungsverfahren zum nachweis eines mutanten gens
CN101415838A (zh) * 2003-09-26 2009-04-22 首科安普有限公司 用滚环扩增法扩增多核苷酸
US20080311564A1 (en) 2004-08-06 2008-12-18 Fort Thomas L Sequences and Methods for Detection of Cytomegalovirus
WO2008001376A2 (en) 2006-06-28 2008-01-03 Yissum Research Development Company Of The Hebrew University Of Jerusalem Detection of analytes in a medium
US9689031B2 (en) 2007-07-14 2017-06-27 Ionian Technologies, Inc. Nicking and extension amplification reaction for the exponential amplification of nucleic acids
JP2012509675A (ja) 2008-11-25 2012-04-26 ジェン−プロウブ インコーポレイテッド 低分子rnaを検出するための組成物および方法、ならびにその使用
US20120028253A1 (en) * 2009-01-05 2012-02-02 Xiaolong Wang Method for amplifying oligonucleotide and small rna by using polymerase-endonuclease chain reaction
US9845495B2 (en) * 2010-12-10 2017-12-19 Abbott Laboratories Method and kit for detecting target nucleic acid
CN102399871B (zh) * 2011-10-24 2014-04-16 中国科学院广州生物医药与健康研究院 耐热等温核酸检测试剂及其试剂盒和检测方法
NZ701145A (en) * 2012-04-09 2016-09-30 Envirologix Inc Compositions and methods for quantifying a nucleic acid sequence in a sample
EP2722399A1 (en) 2012-10-18 2014-04-23 Roche Diagniostics GmbH Method for preventing high molecular weight products during amplification
JP6739339B2 (ja) 2014-01-15 2020-08-12 アボット・ラボラトリーズAbbott Laboratories カバーされた配列変換dnaおよび検出方法
CN103789435B (zh) 2014-01-29 2015-08-26 西安交通大学 一种基于级联恒温扩增的miRNA荧光检测试剂盒及方法
JP6773651B2 (ja) 2014-10-14 2020-10-21 アボット・ラボラトリーズAbbott Laboratories ポリdnaスペーサー配列を有する配列変換およびシグナル増幅dnaならびにそれらを用いた検出方法

Also Published As

Publication number Publication date
EP3207159A2 (en) 2017-08-23
US20160102339A1 (en) 2016-04-14
WO2016059473A3 (en) 2016-06-23
ES2759339T3 (es) 2020-05-08
WO2016059473A2 (en) 2016-04-21
EP3207160A4 (en) 2018-05-23
CN107075585A8 (zh) 2019-02-15
CN107109473B (zh) 2020-11-06
EP3207159A4 (en) 2018-05-30
US10208333B2 (en) 2019-02-19
CN107075585A (zh) 2017-08-18
EP3207159B1 (en) 2019-11-20
US20160102345A1 (en) 2016-04-14
ES2759337T3 (es) 2020-05-08
WO2016059474A2 (en) 2016-04-21
WO2016059474A3 (en) 2016-06-09
CN107109473A (zh) 2017-08-29
US10316353B2 (en) 2019-06-11
EP3207160B1 (en) 2019-11-20
JP6896620B2 (ja) 2021-06-30
JP2017530715A (ja) 2017-10-19
CN107075585B (zh) 2021-07-20
JP2017532044A (ja) 2017-11-02
EP3207160A2 (en) 2017-08-23

Similar Documents

Publication Publication Date Title
JP6739339B2 (ja) カバーされた配列変換dnaおよび検出方法
JP6773651B2 (ja) ポリdnaスペーサー配列を有する配列変換およびシグナル増幅dnaならびにそれらを用いた検出方法
US11492658B2 (en) Sequence conversion and signal amplifier DNA cascade reactions and detection methods using same
US20240117414A1 (en) Sequence conversion and signal amplifier dna having abasic nucleic acids, and detection methods using same
HK1243739B (en) Detection method, composition and kit based on signal amplifier dna cascade reactions with target extension
HK1243140A1 (en) Sequence conversion and signal amplifier dna having poly dna spacer sequences and detection methods using same
HK1243140B (en) Sequence conversion and signal amplifier dna having poly dna spacer sequences and detection methods using same
HK1243136B (zh) 具有锁核酸的序列转换和信号扩增dna以及使用其的检测方法
HK1243136A1 (en) Sequence conversion and signal amplifier dna having locked nucleic acids and detection methods using same

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20171020

A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A711

Effective date: 20180328

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20180328

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20181012

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20181120

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20191015

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20200108

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20200415

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20200901

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20201001

R150 Certificate of patent or registration of utility model

Ref document number: 6773651

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

S533 Written request for registration of change of name

Free format text: JAPANESE INTERMEDIATE CODE: R313533

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250