JP6769962B2 - 癌治療のためのキナーゼ阻害剤プロドラッグ - Google Patents
癌治療のためのキナーゼ阻害剤プロドラッグ Download PDFInfo
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| PCT/US2015/063806 WO2016090174A1 (en) | 2014-12-03 | 2015-12-03 | Kinase inhibitor prodrug for the treatment of cancer |
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| US11110062B2 (en) * | 2017-02-15 | 2021-09-07 | Taiho Pharmaceutical Co., Ltd. | Pharmaceutical composition |
| US11426409B2 (en) | 2017-09-08 | 2022-08-30 | The Regents Of The University Of Colorado | Compounds, compositions and methods for treating or preventing HER-driven drug-resistant cancers |
| MA50251A (fr) | 2017-09-08 | 2021-06-02 | Taiho Pharmaceutical Co Ltd | Agent antitumoral et potentialisateur d'effet antitumoral |
| JP2020534289A (ja) * | 2017-09-14 | 2020-11-26 | ランケナー インスティテュート フォー メディカル リサーチ | がんの治療のための方法および組成物 |
| WO2019125184A1 (en) * | 2017-12-19 | 2019-06-27 | Auckland Uniservices Limited | Use of biomarker in cancer therapy |
| JP2021536507A (ja) * | 2018-09-04 | 2021-12-27 | レイン セラピューティクス インコーポレイティド | Ｈｅｒ駆動性がんを治療または予防するための化合物、組成物、及び方法 |
| WO2020084347A2 (en) * | 2018-10-26 | 2020-04-30 | Auckland Uniservices | Combination of a kinase inhibitor and an immunotherapeutic agent, compositions and methods comprising the same |
| WO2020102304A1 (en) * | 2018-11-13 | 2020-05-22 | Rain Therapeutics Inc. | Combination of a kinase inhibitor and an electrolyte, compositions and methods comprising the same |
| WO2020118251A2 (en) * | 2018-12-07 | 2020-06-11 | The Board Of Trustees Of The Leland Stanford Junior University | Hypoxia targeting compositions and combinations thereof with a parp inhibitor and methods of use thereof |
| CN113840842A (zh) | 2019-02-26 | 2021-12-24 | 詹森生物科技公司 | 利用双特异性抗EGFR/c-Met抗体的联合疗法和患者分层 |
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| US5800992A (en) | 1989-06-07 | 1998-09-01 | Fodor; Stephen P.A. | Method of detecting nucleic acids |
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| TWI377944B (en) * | 2007-06-05 | 2012-12-01 | Hanmi Holdings Co Ltd | Novel amide derivative for inhibiting the growth of cancer cells |
| CN102088979B (zh) * | 2008-05-13 | 2013-10-16 | 阿斯利康(瑞典)有限公司 | 4-(3-氯-2-氟苯胺基)-7-甲氧基-6-{[1-(n-甲基氨基甲酰基甲基)哌啶-4-基]氧基}喹唑啉的富马酸盐 |
| NZ620000A (en) | 2009-03-11 | 2015-07-31 | Auckland Uniservices Ltd | Prodrug forms of kinase inhibitors and their use in cancer therapy |
| EP2473509A4 (en) * | 2009-09-02 | 2013-04-17 | Auckland Uniservices Ltd | KINASEHEMMER, PRODRUG-FORMS THEREOF AND ITS USE IN THERAPY |
| WO2011146945A2 (en) * | 2010-05-21 | 2011-11-24 | Cell Signaling Technology, Inc. | Alk and ros kinase in cancer |
| US8828391B2 (en) | 2011-05-17 | 2014-09-09 | Boehringer Ingelheim International Gmbh | Method for EGFR directed combination treatment of non-small cell lung cancer |
| KR101410902B1 (ko) * | 2011-07-27 | 2014-06-20 | 아스트라제네카 아베 | 암 치료에 유용한 egfr 조절물질로서 2-(2,4,5-치환된-아닐리노)피리미딘 유도체 |
| ES2700231T3 (es) * | 2012-11-21 | 2019-02-14 | Janssen Biotech Inc | Anticuerpos de EGFR/c-Met biespecíficos |
| KR20150119210A (ko) * | 2013-03-14 | 2015-10-23 | 화이자 인코포레이티드 | 비소세포 폐암의 치료를 위한 egfr t790m 억제제와 egfr 억제제의 조합 |
| EP2983591A4 (en) | 2013-04-10 | 2016-12-28 | Threshold Pharmaceuticals Inc | PREDICTIVE AND RESPONSE BIOMARKERS FOR TH-302 CANCER THERAPY |
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| AU2015358384B2 (en) | 2021-03-04 |
| JP2017536408A (ja) | 2017-12-07 |
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| CN107427515B (zh) | 2021-11-16 |
| US20170360790A1 (en) | 2017-12-21 |
| WO2016090174A1 (en) | 2016-06-09 |
| CN114224894A (zh) | 2022-03-25 |
| CN107427515A (zh) | 2017-12-01 |
| EP3226869A1 (en) | 2017-10-11 |
| US10507210B2 (en) | 2019-12-17 |
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