JP6768789B2 - Ａｃｔｈ依存性クッシング症候群を鑑別診断する方法 - Google Patents

Ａｃｔｈ依存性クッシング症候群を鑑別診断する方法 Download PDF

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JP6768789B2
JP6768789B2 JP2018506539A JP2018506539A JP6768789B2 JP 6768789 B2 JP6768789 B2 JP 6768789B2 JP 2018506539 A JP2018506539 A JP 2018506539A JP 2018506539 A JP2018506539 A JP 2018506539A JP 6768789 B2 JP6768789 B2 JP 6768789B2
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acth
syndrome
cushing
cortisol
group
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JP2018529941A5 (enExample
JP2018529941A (ja
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アンドレアス ジー． モライティス，
アンドレアス ジー． モライティス，
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コーセプト セラピューティクス， インコーポレイテッド
コーセプト セラピューティクス， インコーポレイテッド
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/665—Assays involving proteins derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • G01N2333/695—Corticotropin [ACTH]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G01N2800/048—Pituitary or hypothalamic - pituitary relationships, e.g. vasopressin or ADH related

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2018506539A 2015-08-13 2016-08-12 Ａｃｔｈ依存性クッシング症候群を鑑別診断する方法 Expired - Fee Related JP6768789B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562204723P 2015-08-13 2015-08-13
US62/204,723 2015-08-13
PCT/US2016/046904 WO2017027851A1 (en) 2015-08-13 2016-08-12 Method for differentially diagnosing acth-dependent cushing's syndrome

Publications (3)

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JP2018529941A JP2018529941A (ja) 2018-10-11
JP2018529941A5 JP2018529941A5 (enExample) 2019-07-25
JP6768789B2 true JP6768789B2 (ja) 2020-10-14

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JP2018506539A Expired - Fee Related JP6768789B2 (ja) 2015-08-13 2016-08-12 Ａｃｔｈ依存性クッシング症候群を鑑別診断する方法

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Country Link
US (6) US9829495B2 (enExample)
EP (1) EP3335043B1 (enExample)
JP (1) JP6768789B2 (enExample)
KR (1) KR20180052120A (enExample)
AU (1) AU2016305092B2 (enExample)
CA (1) CA2994422A1 (enExample)
ES (1) ES2865334T3 (enExample)
IL (1) IL257439B (enExample)
MX (1) MX383318B (enExample)
WO (1) WO2017027851A1 (enExample)

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PT3600282T (pt) 2017-03-31 2025-11-05 Corcept Therapeutics Inc Moduladores de recetores de glucocorticoides para tratar cancro cervical
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US11234971B2 (en) 2018-12-19 2022-02-01 Corcept Therapeutics Incorporated Methods of treating cancer comprising administration of a glucocorticoid receptor modulator and a cancer chemotherapy agent
CN117281790A (zh) 2018-12-19 2023-12-26 科塞普特治疗公司 含有瑞拉可兰、杂芳基-酮稠合的氮杂十氢化萘化合物的药物制剂
EP3897654B1 (en) * 2018-12-21 2025-01-15 Corcept Therapeutics Incorporated Treatment of hypercoagulopathy in cushing's syndrome by administration of a glucocorticoid receptor modulator
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WO2022134033A1 (en) 2020-12-25 2022-06-30 Corcept Therapeutics Incorporated Methods of preparing heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators
JP2025522619A (ja) * 2022-06-28 2025-07-15 コーセプト セラピューティクス， インコーポレイテッド ヘテロアリール－ケトン縮合アザデカリングルココルチコイド受容体調節因子を調製する方法
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Also Published As

Publication number Publication date
AU2016305092B2 (en) 2022-01-27
US20200088745A1 (en) 2020-03-19
MX2018001803A (es) 2018-05-16
US10495650B2 (en) 2019-12-03
IL257439A (en) 2018-04-30
IL257439B (en) 2020-08-31
KR20180052120A (ko) 2018-05-17
WO2017027851A1 (en) 2017-02-16
US9829495B2 (en) 2017-11-28
US20230324415A1 (en) 2023-10-12
US20180267064A1 (en) 2018-09-20
EP3335043B1 (en) 2021-03-31
EP3335043A4 (en) 2019-01-16
CA2994422A1 (en) 2017-02-16
US20210311079A1 (en) 2021-10-07
HK1255714A1 (en) 2019-08-23
US10006924B2 (en) 2018-06-26
JP2018529941A (ja) 2018-10-11
EP3335043A1 (en) 2018-06-20
MX383318B (es) 2025-03-13
AU2016305092A1 (en) 2018-04-05
US20170045535A1 (en) 2017-02-16
US20180052178A1 (en) 2018-02-22
US11073523B2 (en) 2021-07-27
ES2865334T3 (es) 2021-10-15

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