JP6730319B2 - カルボキサミドハロゲン化ポルフィリン、即ちクロリン及びバクテリオクロリンの低分子量誘導体と、それらの応用 - Google Patents

カルボキサミドハロゲン化ポルフィリン、即ちクロリン及びバクテリオクロリンの低分子量誘導体と、それらの応用 Download PDF

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JP6730319B2
JP6730319B2 JP2017557940A JP2017557940A JP6730319B2 JP 6730319 B2 JP6730319 B2 JP 6730319B2 JP 2017557940 A JP2017557940 A JP 2017557940A JP 2017557940 A JP2017557940 A JP 2017557940A JP 6730319 B2 JP6730319 B2 JP 6730319B2
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hydrogen
formula
carboxamide
porphyrin
skin
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JP2018515498A5 (https=
JP2018515498A (ja
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ナシメント コスタ，ゴンサーロ ペレイラ
ナシメント コスタ，ゴンサーロ ペレイラ
ゴンサルヴェス，ヌノ パウロ フェレイラ
ゴンサルヴェス，ヌノ パウロ フェレイラ
モンテイロ，カルロス ジョルジ ペレイラ
モンテイロ，カルロス ジョルジ ペレイラ
デ アブレウ，アルトゥル カルロス ヘイス
デ アブレウ，アルトゥル カルロス ヘイス
カルドーゾ ソアレス，エルデール ターオ フェラーズ
カルドーゾ ソアレス，エルデール ターオ フェラーズ
ロッチャ，ルイス ガブリエル ボルヘス
ロッチャ，ルイス ガブリエル ボルヘス
アントーニョ シャベレ，ファビョ
アントーニョ シャベレ，ファビョ
ペレイラ，マリア ミゲウンス
ペレイラ，マリア ミゲウンス
シルヴァ アルナウト モレイラ，ルイス ギレルメ ダ
シルヴァ アルナウト モレイラ，ルイス ギレルメ ダ
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Universidade de Coimbra
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    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
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    • C07D—HETEROCYCLIC COMPOUNDS
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    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
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JP2017557940A 2015-05-07 2016-05-06 カルボキサミドハロゲン化ポルフィリン、即ちクロリン及びバクテリオクロリンの低分子量誘導体と、それらの応用 Active JP6730319B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PT108447 2015-05-07
PT10844715 2015-05-07
PCT/IB2016/052606 WO2016178191A1 (en) 2015-05-07 2016-05-06 Low molecular weight derivatives of carboxamide halogenated porphyrins, namely chlorins and bacteriochlorins, and their applications thereof

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JP2018515498A JP2018515498A (ja) 2018-06-14
JP2018515498A5 JP2018515498A5 (https=) 2020-06-18
JP6730319B2 true JP6730319B2 (ja) 2020-07-29

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US (1) US10450322B2 (https=)
EP (1) EP3292129B1 (https=)
JP (1) JP6730319B2 (https=)
CN (1) CN107624114B (https=)
AU (1) AU2016259188B2 (https=)
BR (1) BR112017023948A2 (https=)
CA (1) CA2985187C (https=)
HK (1) HK1245254A1 (https=)
RU (1) RU2718923C2 (https=)
WO (1) WO2016178191A1 (https=)
ZA (1) ZA201707533B (https=)

Families Citing this family (9)

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Publication number Priority date Publication date Assignee Title
WO2017214637A1 (en) 2016-06-10 2017-12-14 Nirvana Sciences Inc. Hydroporphyrin beads with narrow fluorescence emissions
CN110662748A (zh) * 2017-02-03 2020-01-07 尼尔瓦纳科学股份有限公司 用于光声成像的氢卟啉
US11904026B2 (en) 2017-02-03 2024-02-20 Nirvana Sciences Inc. Metallohydroporphyrins for photoacoustic imaging
CN109912607B (zh) * 2018-12-11 2021-01-22 南华大学 一类卟啉-白杨素复合物及其抗肿瘤活性
SG10201811547RA (en) * 2018-12-21 2020-07-29 Oreal Cosmetic use of a short chain fatty acid (scfa) for preventing and/or treating dry skin and/or aged skin
CN109651383B (zh) * 2019-01-25 2021-11-16 华东理工大学 用于光敏剂的化合物及其应用
WO2020236828A1 (en) * 2019-05-20 2020-11-26 Nirvana Sciences Inc. Narrow emission dyes, compositions comprising same, and methods for making and using same
US12570665B2 (en) 2019-06-10 2026-03-10 University Of Massachusetts Compositions comprising fullerenyl mesochlorin nano-photosensitizers with covalently bound antibiotics and their uses in combination therapy
CN116354970B (zh) * 2023-03-28 2024-06-18 大连理工大学 一种卟啉类一氧化碳前药的制备方法及气体-声动力联合治疗应用

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Publication number Priority date Publication date Assignee Title
EP1480638A2 (en) * 2002-01-08 2004-12-01 Emory University Porphyrins with virucidal activity
FR2877943B1 (fr) * 2004-11-16 2008-09-05 Univ De Coimbra Nouveaux derives de porphyrine, notamment chlorines et/ou bacteriochlorine, et leurs applications en therapie photodynamique
GB0819594D0 (en) * 2008-10-24 2008-12-03 Univ Coimbrra Process
JP2013503895A (ja) * 2009-09-02 2013-02-04 ザ リージェンツ オブ ザ ユニバーシティー オブ コロラド，ア ボディー コーポレート 金属ポルフィリン類を使用するミトコンドリア病の処置法
WO2011099602A1 (ja) * 2010-02-12 2011-08-18 学校法人日本大学 ポルフィリン誘導体および放射線力学療法におけるその使用
BR112013001576A2 (pt) * 2010-07-22 2016-07-19 Ceramoptec Gmbh composto tetrapirrólico e composição farmacêutica derivado farmacêuticamente aceitável da mesma e respectivos usos e métodos de terapia fotodinâmica e de diagnóstico e tratamento da artrite e de doenças inflamatórias semelhantes.
CN102166182A (zh) * 2011-01-24 2011-08-31 上海交通大学 纳米探针及其在肿瘤诊断组合物和光动力疗法中的应用
US10456375B2 (en) * 2014-09-30 2019-10-29 Biolitec Unternehmensbeteiligungs Ii Ag Specifically meso-substituted porphyrins and chlorins for photodynamic therapy

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Publication number Publication date
AU2016259188A1 (en) 2017-11-30
WO2016178191A1 (en) 2016-11-10
CN107624114A (zh) 2018-01-23
RU2017138871A3 (https=) 2019-06-11
BR112017023948A2 (en) 2018-07-24
JP2018515498A (ja) 2018-06-14
HK1245254A1 (zh) 2018-08-24
US10450322B2 (en) 2019-10-22
EP3292129A1 (en) 2018-03-14
CN107624114B (zh) 2021-03-23
RU2718923C2 (ru) 2020-04-15
AU2016259188B2 (en) 2019-10-31
ZA201707533B (en) 2019-04-24
RU2017138871A (ru) 2019-06-10
US20180282344A1 (en) 2018-10-04
CA2985187C (en) 2024-01-02
EP3292129B1 (en) 2019-03-27
CA2985187A1 (en) 2016-11-10

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