JP6724004B2 - ステロイドＦＸＲモジュレーター製造のための中間体としての５β−６−アルキル−７−ヒドロキシ−３−オンステロイド - Google Patents

ステロイドＦＸＲモジュレーター製造のための中間体としての５β−６−アルキル−７−ヒドロキシ−３−オンステロイド Download PDF

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JP6724004B2
JP6724004B2 JP2017527816A JP2017527816A JP6724004B2 JP 6724004 B2 JP6724004 B2 JP 6724004B2 JP 2017527816 A JP2017527816 A JP 2017527816A JP 2017527816 A JP2017527816 A JP 2017527816A JP 6724004 B2 JP6724004 B2 JP 6724004B2
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compound
alkyl
halo
reaction
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JP2017538691A5 (cg-RX-API-DMAC7.html
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ウェイマウス‐ウイルソン アレクサンダー
ウェイマウス‐ウイルソン アレクサンダー
コムスタ ゾフィア
コムスタ ゾフィア
ボーイデル ジェームス
ボーイデル ジェームス
ウオリス ローラ
ウオリス ローラ
バートレット ネイサン
バートレット ネイサン
シェルボーン モントセラト
シェルボーン モントセラト
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エヌゼットピー ユーケー リミテッド
エヌゼットピー ユーケー リミテッド
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Priority claimed from GBGB1420594.2A external-priority patent/GB201420594D0/en
Priority claimed from GBGB1420593.4A external-priority patent/GB201420593D0/en
Priority claimed from GBGB1505674.0A external-priority patent/GB201505674D0/en
Application filed by エヌゼットピー ユーケー リミテッド, エヌゼットピー ユーケー リミテッド filed Critical エヌゼットピー ユーケー リミテッド
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2017527816A 2014-11-19 2015-11-19 ステロイドＦＸＲモジュレーター製造のための中間体としての５β−６−アルキル−７−ヒドロキシ−３−オンステロイド Active JP6724004B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB1420593.4 2014-11-19
GBGB1420594.2A GB201420594D0 (en) 2014-11-19 2014-11-19 Compounds
GBGB1420593.4A GB201420593D0 (en) 2014-11-19 2014-11-19 Compounds
GB1420594.2 2014-11-19
GBGB1505674.0A GB201505674D0 (en) 2015-04-01 2015-04-01 Compounds
GB1505674.0 2015-04-01
PCT/GB2015/053517 WO2016079518A1 (en) 2014-11-19 2015-11-19 5.beta.-6-alkyl-7-hydroxy-3-one steroids as intermediates for the production of steroidal fxr modulators

Publications (3)

Publication Number Publication Date
JP2017538691A JP2017538691A (ja) 2017-12-28
JP2017538691A5 JP2017538691A5 (cg-RX-API-DMAC7.html) 2019-01-10
JP6724004B2 true JP6724004B2 (ja) 2020-07-15

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JP2017527816A Active JP6724004B2 (ja) 2014-11-19 2015-11-19 ステロイドＦＸＲモジュレーター製造のための中間体としての５β−６−アルキル−７−ヒドロキシ−３−オンステロイド

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US (1) US10131688B2 (cg-RX-API-DMAC7.html)
EP (1) EP3221332B1 (cg-RX-API-DMAC7.html)
JP (1) JP6724004B2 (cg-RX-API-DMAC7.html)
KR (1) KR102526632B1 (cg-RX-API-DMAC7.html)
CN (1) CN107108687B (cg-RX-API-DMAC7.html)
CA (1) CA2968301C (cg-RX-API-DMAC7.html)
DK (1) DK3221332T3 (cg-RX-API-DMAC7.html)
EA (1) EA033445B1 (cg-RX-API-DMAC7.html)
ES (1) ES2733643T3 (cg-RX-API-DMAC7.html)
HK (1) HK1244285B (cg-RX-API-DMAC7.html)
MX (1) MX375864B (cg-RX-API-DMAC7.html)
PL (1) PL3221332T3 (cg-RX-API-DMAC7.html)
TW (1) TWI686400B (cg-RX-API-DMAC7.html)
WO (1) WO2016079518A1 (cg-RX-API-DMAC7.html)

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CN111138509B (zh) * 2018-11-02 2022-12-06 东莞东阳光药物研发有限公司 奥贝胆酸的制备方法
CN113135970B (zh) * 2020-01-20 2024-11-22 成都贝诺科成生物科技有限公司 一种具有抗芽孢活性的化合物及其药用组合物

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TWI686400B (zh) 2020-03-01
JP2017538691A (ja) 2017-12-28
EA201790881A1 (ru) 2017-11-30
EP3221332B1 (en) 2019-04-24
CN107108687B (zh) 2019-10-29
MX375864B (es) 2025-03-07
CN107108687A (zh) 2017-08-29
WO2016079518A1 (en) 2016-05-26
DK3221332T3 (da) 2019-07-29
HK1244285B (en) 2020-06-05
PL3221332T3 (pl) 2019-10-31
CA2968301C (en) 2023-05-16
ES2733643T3 (es) 2019-12-02
TW201629081A (zh) 2016-08-16
CA2968301A1 (en) 2016-05-26
US10131688B2 (en) 2018-11-20
EP3221332A1 (en) 2017-09-27
MX2017006564A (es) 2018-01-26
KR102526632B1 (ko) 2023-04-27
KR20170099895A (ko) 2017-09-01
US20170320907A1 (en) 2017-11-09
EA201790881A8 (ru) 2019-07-31
EA033445B1 (ru) 2019-10-31

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