JP6715833B2 - 白血病の治療に使用するためのキノリンカルボキサミド - Google Patents
白血病の治療に使用するためのキノリンカルボキサミド Download PDFInfo
- Publication number
- JP6715833B2 JP6715833B2 JP2017525360A JP2017525360A JP6715833B2 JP 6715833 B2 JP6715833 B2 JP 6715833B2 JP 2017525360 A JP2017525360 A JP 2017525360A JP 2017525360 A JP2017525360 A JP 2017525360A JP 6715833 B2 JP6715833 B2 JP 6715833B2
- Authority
- JP
- Japan
- Prior art keywords
- leukemia
- compound
- pharmaceutically acceptable
- treatment
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14193776 | 2014-11-19 | ||
| EP14193776.3 | 2014-11-19 | ||
| PCT/EP2015/075769 WO2016078921A1 (en) | 2014-11-19 | 2015-11-05 | Quinoline carboxamides for use in the treatment of leukemia |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017534652A JP2017534652A (ja) | 2017-11-24 |
| JP2017534652A5 JP2017534652A5 (enrdf_load_stackoverflow) | 2018-12-06 |
| JP6715833B2 true JP6715833B2 (ja) | 2020-07-01 |
Family
ID=51951635
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017525360A Active JP6715833B2 (ja) | 2014-11-19 | 2015-11-05 | 白血病の治療に使用するためのキノリンカルボキサミド |
Country Status (15)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3168070A1 (en) | 2020-03-03 | 2021-09-10 | Active Biotech Ab | Tasquinimod or a pharmaceutically acceptable salt thereof for use in combination therapy |
| CA3185531A1 (en) | 2020-07-23 | 2022-01-27 | Rebekka Katharina Marita SCHNEIDER-KRAMANN | S100 proteins as novel therapeutic targets in myeloproliferative neoplasms |
| KR20230133317A (ko) | 2021-01-18 | 2023-09-19 | 액티브 바이오테크 에이비 | 골수이형성 증후군의 치료에 이용하기 위한 타스퀴니모드또는 이의 약제학적으로 허용가능한 염 |
| IL308542A (en) | 2021-05-25 | 2024-01-01 | Active Biotech Ab | Multiparticles of tesquinimod and their use |
| WO2023275248A1 (en) | 2021-07-02 | 2023-01-05 | Active Biotech Ab | A pharmaceutical product containing tasquinimod and a method for assessing the purity of said product |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9801474D0 (sv) | 1998-04-27 | 1998-04-27 | Active Biotech Ab | Quinoline Derivatives |
| SE9802549D0 (sv) | 1998-07-15 | 1998-07-15 | Active Biotech Ab | Quinoline derivatives |
| SE0002320D0 (sv) | 1999-10-25 | 2000-06-21 | Active Biotech Ab | Malignant tumors |
| SE0201778D0 (sv) | 2002-06-12 | 2002-06-12 | Active Biotech Ab | Process for the manufacture of quinoline derivatives |
| SE0400235D0 (sv) | 2004-02-06 | 2004-02-06 | Active Biotech Ab | New composition containing quinoline compounds |
| KR101855195B1 (ko) | 2010-07-09 | 2018-05-08 | 액티브 바이오테크 에이비 | 퀴놀린-3-카르복사미드의 제조 방법 |
| EP2537517A1 (en) | 2011-06-22 | 2012-12-26 | Active Biotech AB | Deuterium-enriched 4-hydroxy-5-methoxy-n,1-dimethyl-2-oxo-n-[(4-trifluoro-methyl)phenyl]-1,2-dihydroquinoline-3-carboxamide |
| WO2015095833A1 (en) * | 2013-12-20 | 2015-06-25 | Biomed Valley Discoveries, Inc. | Treatment of hematologic cancers |
-
2015
- 2015-11-05 US US15/525,086 patent/US10300053B2/en active Active
- 2015-11-05 BR BR112017009854-7A patent/BR112017009854B1/pt active IP Right Grant
- 2015-11-05 EP EP15790143.0A patent/EP3180005B1/en active Active
- 2015-11-05 MX MX2017006110A patent/MX379401B/es unknown
- 2015-11-05 KR KR1020177015989A patent/KR102525805B1/ko active Active
- 2015-11-05 JP JP2017525360A patent/JP6715833B2/ja active Active
- 2015-11-05 CN CN201580062750.4A patent/CN107072989B/zh active Active
- 2015-11-05 NZ NZ732704A patent/NZ732704A/en unknown
- 2015-11-05 CA CA2967112A patent/CA2967112C/en active Active
- 2015-11-05 WO PCT/EP2015/075769 patent/WO2016078921A1/en active Application Filing
- 2015-11-05 PL PL15790143T patent/PL3180005T3/pl unknown
- 2015-11-05 EA EA201791099A patent/EA031643B1/ru not_active IP Right Cessation
- 2015-11-05 ES ES15790143.0T patent/ES2663836T3/es active Active
- 2015-11-05 AU AU2015348778A patent/AU2015348778B2/en active Active
-
2017
- 2017-05-09 IL IL252174A patent/IL252174B/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| KR102525805B1 (ko) | 2023-04-25 |
| EA201791099A1 (ru) | 2017-10-31 |
| IL252174B (en) | 2021-02-28 |
| CA2967112C (en) | 2023-05-16 |
| AU2015348778B2 (en) | 2020-12-24 |
| MX2017006110A (es) | 2017-07-27 |
| EP3180005A1 (en) | 2017-06-21 |
| CA2967112A1 (en) | 2016-05-26 |
| EP3180005B1 (en) | 2017-12-27 |
| US10300053B2 (en) | 2019-05-28 |
| JP2017534652A (ja) | 2017-11-24 |
| IL252174A0 (en) | 2017-07-31 |
| US20170319568A1 (en) | 2017-11-09 |
| KR20170083121A (ko) | 2017-07-17 |
| CN107072989B (zh) | 2020-07-03 |
| AU2015348778A1 (en) | 2017-06-29 |
| MX379401B (es) | 2025-03-11 |
| PL3180005T3 (pl) | 2018-06-29 |
| EA031643B1 (ru) | 2019-01-31 |
| CN107072989A (zh) | 2017-08-18 |
| ES2663836T3 (es) | 2018-04-17 |
| BR112017009854A2 (pt) | 2018-01-16 |
| WO2016078921A1 (en) | 2016-05-26 |
| BR112017009854B1 (pt) | 2022-08-23 |
| NZ732704A (en) | 2022-01-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6715833B2 (ja) | 白血病の治療に使用するためのキノリンカルボキサミド | |
| US10314836B2 (en) | Quinoline carboxamides for use in the treatment of multiple myeloma | |
| Bose et al. | A review of tumour lysis syndrome with targeted therapies and the role of rasburicase | |
| JP2010500371A (ja) | 抗ｃｓ１抗体に基づく組合せ療法を用いて多発性骨髄腫を処置する方法 | |
| TW202019409A (zh) | Bcl-2抑制劑與利妥昔單抗和/或苯達莫司汀或bcl-2抑制劑與chop聯合用藥的協同抗腫瘤作用 | |
| RU2012144844A (ru) | Комплексные соединения железа(iii) для лечения и профилактики симптомов железодефицита и железодефицитной анемии | |
| Zhao et al. | Adaptive immune cells are necessary for the enhanced therapeutic effect of sorafenib-loaded nanoparticles | |
| WO2019074116A1 (ja) | Ａｘｌ阻害剤を有効成分として含む固形がん治療剤 | |
| JP2017534652A5 (enrdf_load_stackoverflow) | ||
| HK1237658A1 (en) | Quinoline carboxamides for use in the treatment of leukemia | |
| HK1237658B (en) | Quinoline carboxamides for use in the treatment of leukemia | |
| EP3880207A1 (en) | Combination of a mcl-1 inhibitor and midostaurin, uses and pharmaceutical compositions thereof | |
| US10154989B2 (en) | Methods of managing graft versus host disease (GvHD) using indole carboxyaldehydes or derivatives thereof | |
| BR112017004947B1 (pt) | Uso de um composto ou sal farmaceuticamente aceitável | |
| HK1226643A1 (en) | Quinoline carboxamides for use in the treatment of multiple myeloma | |
| HK1226643B (en) | Quinoline carboxamides for use in the treatment of multiple myeloma | |
| JP2005041801A (ja) | 細胞移植療法後の予後改善剤 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20181024 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20181024 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20190712 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20190711 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20191001 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A821 Effective date: 20200110 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20200522 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20200609 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 6715833 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |