JP6698681B2 - 糖タンパク質のグリカン含量のレベルを操作するためのプロセス - Google Patents

糖タンパク質のグリカン含量のレベルを操作するためのプロセス Download PDF

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JP6698681B2
JP6698681B2 JP2017547931A JP2017547931A JP6698681B2 JP 6698681 B2 JP6698681 B2 JP 6698681B2 JP 2017547931 A JP2017547931 A JP 2017547931A JP 2017547931 A JP2017547931 A JP 2017547931A JP 6698681 B2 JP6698681 B2 JP 6698681B2
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ライスク，ダニエル・アール
トレンタランジ，マイケル・ティー
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アムジエン・インコーポレーテツド
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    • C12P21/005—Glycopeptides, glycoproteins
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    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • C07K16/242—Lymphotoxin [LT]
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
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    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41—Glycosylation, sialylation, or fucosylation
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    • C07K2317/00—Immunoglobulins specific features
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    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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    • C12N2500/00—Specific components of cell culture medium
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    • C12N2523/00—Culture process characterised by temperature

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  • Bioinformatics & Cheminformatics (AREA)
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  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2017547931A 2014-12-01 2015-12-01 糖タンパク質のグリカン含量のレベルを操作するためのプロセス Active JP6698681B2 (ja)

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US201462085759P 2014-12-01 2014-12-01
US62/085,759 2014-12-01
PCT/US2015/063271 WO2016089919A1 (en) 2014-12-01 2015-12-01 Process for manipulating the level of glycan content of a glycoprotein

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JP2017538446A JP2017538446A (ja) 2017-12-28
JP2017538446A5 JP2017538446A5 (cg-RX-API-DMAC7.html) 2019-01-17
JP6698681B2 true JP6698681B2 (ja) 2020-05-27

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JP2017547931A Active JP6698681B2 (ja) 2014-12-01 2015-12-01 糖タンパク質のグリカン含量のレベルを操作するためのプロセス
JP2020080270A Active JP7066775B2 (ja) 2014-12-01 2020-04-30 糖タンパク質のグリカン含量のレベルを操作するためのプロセス
JP2022072126A Pending JP2022101669A (ja) 2014-12-01 2022-04-26 糖タンパク質のグリカン含量のレベルを操作するためのプロセス
JP2024063188A Pending JP2024095777A (ja) 2014-12-01 2024-04-10 糖タンパク質のグリカン含量のレベルを操作するためのプロセス

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JP2020080270A Active JP7066775B2 (ja) 2014-12-01 2020-04-30 糖タンパク質のグリカン含量のレベルを操作するためのプロセス
JP2022072126A Pending JP2022101669A (ja) 2014-12-01 2022-04-26 糖タンパク質のグリカン含量のレベルを操作するためのプロセス
JP2024063188A Pending JP2024095777A (ja) 2014-12-01 2024-04-10 糖タンパク質のグリカン含量のレベルを操作するためのプロセス

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