JP6669722B2 - Cd3結合ドメイン - Google Patents
Cd3結合ドメイン Download PDFInfo
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- JP6669722B2 JP6669722B2 JP2017506890A JP2017506890A JP6669722B2 JP 6669722 B2 JP6669722 B2 JP 6669722B2 JP 2017506890 A JP2017506890 A JP 2017506890A JP 2017506890 A JP2017506890 A JP 2017506890A JP 6669722 B2 JP6669722 B2 JP 6669722B2
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| US12195533B2 (en) * | 2018-07-24 | 2025-01-14 | Inhibrx Biosciences, Inc. | Multispecific polypeptide constructs containing a constrained CD3 binding domain and a receptor binding region and methods of using the same |
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| WO2020076977A2 (en) | 2018-10-11 | 2020-04-16 | Inhibrx, Inc. | Dll3 single domain antibodies and therapeutic compositions thereof |
| JP7698581B2 (ja) * | 2019-03-29 | 2025-06-25 | グリーン・クロス・コーポレイション | 抗メソテリン抗体、抗cd3抗体又は抗egfr抗体を含む融合タンパク質、それを含む二重特異性又は三重特異性抗体、及びその使用 |
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| PE20230389A1 (es) | 2020-05-27 | 2023-03-06 | Janssen Biotech Inc | Proteinas que comprenden dominios de union al antigeno de cd3 y usos de estas |
| IL306111A (en) | 2021-04-30 | 2023-11-01 | Hoffmann La Roche | Dosage for combined treatment with BISPIFIC ANTI-CD20/ANTI-CD3 antibody and anti-CD79B antibody for antiretroviral drugs |
| EP4329800A1 (en) | 2021-04-30 | 2024-03-06 | F. Hoffmann-La Roche AG | Dosing for treatment with anti-cd20/anti-cd3 bispecific antibody |
| WO2022263507A1 (en) | 2021-06-17 | 2022-12-22 | Boehringer Ingelheim International Gmbh | Novel tri-specific binding molecules |
| CN116375868A (zh) * | 2021-12-31 | 2023-07-04 | 康源博创生物科技(北京)有限公司 | 一种抗cd3的人源化抗体及其在制备双特异性抗体中的应用 |
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| EP2698431B1 (en) * | 2011-03-30 | 2020-09-09 | Chugai Seiyaku Kabushiki Kaisha | Retention of antigen-binding molecules in blood plasma and method for modifying immunogenicity |
| SI2714733T1 (sl) * | 2011-05-21 | 2019-06-28 | Macrogenics, Inc. | CD3-vezavne molekule sposobne vezave na humani ali ne-humani CD3 |
| MX2015008446A (es) * | 2012-12-28 | 2016-10-26 | Abbvie Inc | Composiciones de proteinas de union multivalentes. |
| US10131710B2 (en) | 2013-01-14 | 2018-11-20 | Xencor, Inc. | Optimized antibody variable regions |
| EP2948475A2 (en) | 2013-01-23 | 2015-12-02 | AbbVie Inc. | Methods and compositions for modulating an immune response |
| EP3030581B1 (en) * | 2013-08-07 | 2021-01-20 | Affimed GmbH | Antibody binding sites specific for egfrviii |
| US9212225B1 (en) * | 2014-07-01 | 2015-12-15 | Amphivena Therapeutics, Inc. | Bispecific CD33 and CD3 binding proteins |
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2015
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| Publication number | Publication date |
|---|---|
| CN107001468A (zh) | 2017-08-01 |
| EP2982693A1 (en) | 2016-02-10 |
| EP3177646A1 (en) | 2017-06-14 |
| US20160039934A1 (en) | 2016-02-11 |
| US10066015B2 (en) | 2018-09-04 |
| BR112017002422B1 (pt) | 2024-02-20 |
| RU2017105120A (ru) | 2018-09-10 |
| RU2017105120A3 (enExample) | 2019-02-20 |
| CN107001468B (zh) | 2021-04-09 |
| JP2017529067A (ja) | 2017-10-05 |
| SI3177646T1 (sl) | 2021-04-30 |
| RU2742691C2 (ru) | 2021-02-09 |
| EP3177646B1 (en) | 2020-10-07 |
| WO2016020444A1 (en) | 2016-02-11 |
| CA2957462C (en) | 2023-10-17 |
| CA2957462A1 (en) | 2016-02-11 |
| HUE051919T2 (hu) | 2021-04-28 |
| LT3177646T (lt) | 2021-01-11 |
| HRP20202024T1 (hr) | 2021-02-19 |
| AU2015299039B2 (en) | 2021-01-21 |
| BR112017002422A2 (pt) | 2017-11-28 |
| DK3177646T3 (da) | 2020-12-07 |
| AU2015299039A1 (en) | 2017-03-02 |
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