JP6662789B2 - 脳アミロイドーシスを処置及び／又は予防する投与計画 - Google Patents
脳アミロイドーシスを処置及び／又は予防する投与計画 Download PDFInfo
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
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|---|---|---|---|
| US201461979408P | 2014-04-14 | 2014-04-14 | |
| US61/979,408 | 2014-04-14 | ||
| US14/684,967 | 2015-04-13 | ||
| US14/684,967 US9675627B2 (en) | 2014-04-14 | 2015-04-13 | Dosing regimens for treating and/or preventing cerebral amyloidoses |
| PCT/US2015/025733 WO2015160796A1 (en) | 2014-04-14 | 2015-04-14 | Dosing regimens for treating and/or preventing cerebral amyloidoses |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017511372A JP2017511372A (ja) | 2017-04-20 |
| JP2017511372A5 JP2017511372A5 (https=) | 2019-05-09 |
| JP6662789B2 true JP6662789B2 (ja) | 2020-03-11 |
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| US (2) | US9675627B2 (https=) |
| EP (1) | EP3131547A1 (https=) |
| JP (1) | JP6662789B2 (https=) |
| KR (1) | KR20170003576A (https=) |
| CN (1) | CN107148270A (https=) |
| AU (1) | AU2015247859B2 (https=) |
| CA (1) | CA2945707A1 (https=) |
| HK (1) | HK1243643A1 (https=) |
| SG (1) | SG11201610349SA (https=) |
| WO (1) | WO2015160796A1 (https=) |
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| WO2011049787A1 (en) * | 2009-10-19 | 2011-04-28 | Amicus Therapeutics, Inc. | Method for treating alzheimer's disease using pharmacological chaperones to increase the activity of gangliosidases |
| AR106977A1 (es) | 2015-12-14 | 2018-03-07 | Amicus Therapeutics Inc | Compuestos para el tratamiento de la enfermedad de alzheimer y/o la angiopatía amiloide cerebral |
| US20220184185A1 (en) | 2018-07-25 | 2022-06-16 | Modernatx, Inc. | Mrna based enzyme replacement therapy combined with a pharmacological chaperone for the treatment of lysosomal storage disorders |
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| US4407957A (en) | 1981-03-13 | 1983-10-04 | Damon Corporation | Reversible microencapsulation of a core material |
| CA2109085C (en) | 1991-04-25 | 2003-03-11 | Keith E. Dionne | Implantable biocompatible immunoisolatory vehicle for delivery of selected therapeutic products |
| US5766846A (en) | 1992-07-10 | 1998-06-16 | Athena Neurosciences | Methods of screening for compounds which inhibit soluble β-amyloid peptide production |
| US5383851A (en) | 1992-07-24 | 1995-01-24 | Bioject Inc. | Needleless hypodermic injection device |
| US5569189A (en) | 1992-09-28 | 1996-10-29 | Equidyne Systems, Inc. | hypodermic jet injector |
| ES2179831T3 (es) | 1992-09-29 | 2003-02-01 | Inhale Therapeutic Syst | Liberacion en los pulmones de fragmentos activos de hormona paratiroidiana. |
| FR2718357B1 (fr) | 1994-04-06 | 1997-10-03 | Defarges Alain Moreau | Perfectionnements apportés à un dispositif d'injection par jet sans aiguille. |
| US5599302A (en) | 1995-01-09 | 1997-02-04 | Medi-Ject Corporation | Medical injection system and method, gas spring thereof and launching device using gas spring |
| US5780014A (en) | 1995-04-14 | 1998-07-14 | Inhale Therapeutic Systems | Method and apparatus for pulmonary administration of dry powder alpha 1-antitrypsin |
| US5654007A (en) | 1995-06-07 | 1997-08-05 | Inhale Therapeutic Systems | Methods and system for processing dispersible fine powders |
| US6274597B1 (en) | 1998-06-01 | 2001-08-14 | Mount Sinai School Of Medicine Of New York University | Method of enhancing lysosomal α-Galactosidase A |
| US20050031651A1 (en) | 2002-12-24 | 2005-02-10 | Francine Gervais | Therapeutic formulations for the treatment of beta-amyloid related diseases |
| US20070066543A1 (en) | 2003-05-22 | 2007-03-22 | The Hospital For Sick Children | Treatment of tay sachs or sandhoff diseases by enhancing hexosaminidase activity |
| CN101541172A (zh) | 2005-06-08 | 2009-09-23 | 阿米库斯治疗学公司 | 溶酶体酶编码基因突变相关的cns紊乱的治疗 |
| ES2573498T3 (es) * | 2006-05-16 | 2016-06-08 | Amicus Therapeutics, Inc. | Opciones de tratamiento para la enfermedad de Fabry |
| JP5303458B2 (ja) | 2006-06-23 | 2013-10-02 | アミークス セラピューティックス インコーポレイテッド | β−グルコセレブロシダーゼの活性増強による神経学的疾患の治療方法 |
| EP2150254A4 (en) * | 2007-04-26 | 2010-11-10 | Amicus Therapeutics Inc | DOSAGES FOR THE TREATMENT OF LYSOSOMAL STORAGE DISEASES WITH PHARMACOLOGICAL CHAPTERONES |
| WO2011011181A1 (en) | 2009-07-01 | 2011-01-27 | Amicus Therapeutics, Inc. | Pharmacological chaperones for the treatment of alzheimer's disease |
| WO2011049787A1 (en) * | 2009-10-19 | 2011-04-28 | Amicus Therapeutics, Inc. | Method for treating alzheimer's disease using pharmacological chaperones to increase the activity of gangliosidases |
| CN103974619B (zh) * | 2011-03-11 | 2017-02-15 | 阿米库斯治疗学公司 | 治疗法布里病的给药方案 |
| CA2860085A1 (en) * | 2011-12-22 | 2013-06-27 | Centogene Ip Gmbh | Combination of a compound having the ability to rearrange a lysosomal enzyme and ambroxol and/or a derivative of ambroxol |
| HRP20210398T1 (hr) * | 2012-05-03 | 2021-05-28 | Amicus Therapeutics, Inc. | Režimi doziranja za liječenje pompeove bolesti |
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2015
- 2015-04-13 US US14/684,967 patent/US9675627B2/en active Active
- 2015-04-14 JP JP2016562965A patent/JP6662789B2/ja not_active Expired - Fee Related
- 2015-04-14 WO PCT/US2015/025733 patent/WO2015160796A1/en not_active Ceased
- 2015-04-14 CA CA2945707A patent/CA2945707A1/en not_active Abandoned
- 2015-04-14 EP EP15719362.4A patent/EP3131547A1/en not_active Withdrawn
- 2015-04-14 KR KR1020167031756A patent/KR20170003576A/ko not_active Withdrawn
- 2015-04-14 CN CN201580031471.1A patent/CN107148270A/zh active Pending
- 2015-04-14 HK HK18103256.3A patent/HK1243643A1/zh unknown
- 2015-04-14 AU AU2015247859A patent/AU2015247859B2/en not_active Ceased
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|---|---|
| AU2015247859B2 (en) | 2020-03-26 |
| JP2017511372A (ja) | 2017-04-20 |
| US9675627B2 (en) | 2017-06-13 |
| WO2015160796A1 (en) | 2015-10-22 |
| HK1243643A1 (zh) | 2018-07-20 |
| KR20170003576A (ko) | 2017-01-09 |
| EP3131547A1 (en) | 2017-02-22 |
| US20170273996A1 (en) | 2017-09-28 |
| SG11201610349SA (en) | 2017-01-27 |
| CA2945707A1 (en) | 2015-10-22 |
| AU2015247859A1 (en) | 2016-12-01 |
| US20160008383A1 (en) | 2016-01-14 |
| CN107148270A (zh) | 2017-09-08 |
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