JP6649540B2 - 置換されたヘテロアリール化合物および使用方法 - Google Patents
置換されたヘテロアリール化合物および使用方法 Download PDFInfo
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- JP6649540B2 JP6649540B2 JP2017519817A JP2017519817A JP6649540B2 JP 6649540 B2 JP6649540 B2 JP 6649540B2 JP 2017519817 A JP2017519817 A JP 2017519817A JP 2017519817 A JP2017519817 A JP 2017519817A JP 6649540 B2 JP6649540 B2 JP 6649540B2
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- Prior art keywords
- cycloalkyl
- membered heterocyclyl
- alkyl
- compound
- membered heteroaryl
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Landscapes
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| US62/063,460 | 2014-10-14 | ||
| PCT/US2015/055034 WO2016060963A1 (en) | 2014-10-14 | 2015-10-10 | Substituted heteroaryl compounds and methods of use |
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| CN109776522B (zh) * | 2017-10-30 | 2020-12-29 | 广东东阳光药业有限公司 | 取代的杂芳基化合物及其组合物和用途 |
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| SI3752501T1 (sl) | 2018-02-13 | 2023-08-31 | Gilead Sciences, Inc. | Inhibitorji pd-1/pd-l1 |
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| SI3820572T1 (sl) | 2018-07-13 | 2023-12-29 | Gilead Sciences, Inc. | Inhibitorji pd-1/pd-l1 |
| JP7158577B2 (ja) | 2018-10-24 | 2022-10-21 | ギリアード サイエンシーズ， インコーポレイテッド | Ｐｄ－１／ｐｄ－ｌ１阻害剤 |
| EP3876939A4 (en) | 2018-11-07 | 2022-08-10 | Dana-Farber Cancer Institute, Inc. | Benzothiazole derivatives and 7-aza-benzothiazole derivatives as janus kinase 2 inhibitors and uses thereof |
| US12157730B2 (en) | 2019-03-19 | 2024-12-03 | Voronoi Inc. | Heteroaryl derivative, method for producing same, and pharmaceutical composition comprising same as effective component |
| MA55380A (fr) | 2019-03-19 | 2022-01-26 | B2Sbio Inc | Dérivé hétéroaryle, son procédé de production et composition pharmaceutique le comprenant en tant que constituant efficace |
| WO2021083185A1 (zh) * | 2019-10-29 | 2021-05-06 | 沈阳中化农药化工研发有限公司 | 含嘧啶的哌啶胺类化合物及其制备方法和用途 |
| BR112022022409A2 (pt) | 2020-05-06 | 2023-02-07 | Ajax Therapeutics Inc | 6-heteroarilóxi benzimidazóis e azabenzimidazóis como inibidores de jak2 |
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| JP4812763B2 (ja) | 2004-05-18 | 2011-11-09 | ライジェル ファーマシューティカルズ， インコーポレイテッド | シクロアルキル置換ピリミジンジアミン化合物およびそれらの用途 |
| GB2420559B (en) | 2004-11-15 | 2008-08-06 | Rigel Pharmaceuticals Inc | Stereoisomerically enriched 3-aminocarbonyl bicycloheptene pyrimidinediamine compounds and their uses |
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-
2015
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- 2015-10-10 ES ES15851260T patent/ES2699948T3/es active Active
- 2015-10-10 EP EP15851260.8A patent/EP3206691B1/en active Active
- 2015-10-10 US US14/880,199 patent/US10059689B2/en active Active
- 2015-10-10 WO PCT/US2015/055034 patent/WO2016060963A1/en not_active Ceased
- 2015-10-12 TW TW104133416A patent/TW201617338A/zh unknown
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| US10059689B2 (en) | 2018-08-28 |
| JP2017531000A (ja) | 2017-10-19 |
| EP3206691A4 (en) | 2018-04-11 |
| TW201617338A (zh) | 2016-05-16 |
| EP3206691B1 (en) | 2018-09-19 |
| EP3206691A1 (en) | 2017-08-23 |
| ES2699948T3 (es) | 2019-02-13 |
| US20160229837A1 (en) | 2016-08-11 |
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