JP6649540B2 - 置換されたヘテロアリール化合物および使用方法 - Google Patents
置換されたヘテロアリール化合物および使用方法 Download PDFInfo
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- JP6649540B2 JP6649540B2 JP2017519817A JP2017519817A JP6649540B2 JP 6649540 B2 JP6649540 B2 JP 6649540B2 JP 2017519817 A JP2017519817 A JP 2017519817A JP 2017519817 A JP2017519817 A JP 2017519817A JP 6649540 B2 JP6649540 B2 JP 6649540B2
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- Prior art keywords
- cycloalkyl
- membered heterocyclyl
- alkyl
- compound
- membered heteroaryl
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Landscapes
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| US201462063460P | 2014-10-14 | 2014-10-14 | |
| US62/063,460 | 2014-10-14 | ||
| PCT/US2015/055034 WO2016060963A1 (en) | 2014-10-14 | 2015-10-10 | Substituted heteroaryl compounds and methods of use |
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| CN109776522B (zh) * | 2017-10-30 | 2020-12-29 | 广东东阳光药业有限公司 | 取代的杂芳基化合物及其组合物和用途 |
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| US10899735B2 (en) | 2018-04-19 | 2021-01-26 | Gilead Sciences, Inc. | PD-1/PD-L1 inhibitors |
| UA126421C2 (uk) | 2018-07-13 | 2022-09-28 | Гіліад Сайєнсіз, Інк. | Інгібітори pd-1/pd-l1 |
| AU2019366355B2 (en) | 2018-10-24 | 2022-10-13 | Gilead Sciences, Inc. | PD-1/PD-L1 inhibitors |
| US12415816B2 (en) | 2018-11-07 | 2025-09-16 | Dana-Farber Cancer Institute, Inc. | Benzothiazole derivatives and 7-aza-benzothiazole derivatives as janus kinase 2 inhibitors and uses thereof |
| US12509455B2 (en) | 2018-11-07 | 2025-12-30 | Dana-Farber Cancer Institute, Inc. | Imidazopyridine derivatives and aza-imidazopyridine derivatives as Janus kinase 2 inhibitors and uses thereof |
| CN113993866B (zh) | 2019-03-19 | 2022-10-28 | 株式会社沃若诺伊 | 杂芳基衍生物、其制备方法、及含其作为有效成分的药物组合物 |
| US12157730B2 (en) | 2019-03-19 | 2024-12-03 | Voronoi Inc. | Heteroaryl derivative, method for producing same, and pharmaceutical composition comprising same as effective component |
| WO2021083185A1 (zh) * | 2019-10-29 | 2021-05-06 | 沈阳中化农药化工研发有限公司 | 含嘧啶的哌啶胺类化合物及其制备方法和用途 |
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| EP1763514A2 (en) | 2004-05-18 | 2007-03-21 | Rigel Pharmaceuticals, Inc. | Cycloalkyl substituted pyrimidinediamine compounds and their uses |
| GB2420559B (en) | 2004-11-15 | 2008-08-06 | Rigel Pharmaceuticals Inc | Stereoisomerically enriched 3-aminocarbonyl bicycloheptene pyrimidinediamine compounds and their uses |
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-
2015
- 2015-10-10 JP JP2017519817A patent/JP6649540B2/ja active Active
- 2015-10-10 US US14/880,199 patent/US10059689B2/en active Active
- 2015-10-10 EP EP15851260.8A patent/EP3206691B1/en active Active
- 2015-10-10 ES ES15851260T patent/ES2699948T3/es active Active
- 2015-10-10 WO PCT/US2015/055034 patent/WO2016060963A1/en not_active Ceased
- 2015-10-12 TW TW104133416A patent/TW201617338A/zh unknown
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| WO2016060963A1 (en) | 2016-04-21 |
| EP3206691B1 (en) | 2018-09-19 |
| JP2017531000A (ja) | 2017-10-19 |
| ES2699948T3 (es) | 2019-02-13 |
| TW201617338A (zh) | 2016-05-16 |
| US20160229837A1 (en) | 2016-08-11 |
| US10059689B2 (en) | 2018-08-28 |
| EP3206691A1 (en) | 2017-08-23 |
| EP3206691A4 (en) | 2018-04-11 |
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