JP6641263B2 - 神経障害性疼痛の処置方法 - Google Patents

神経障害性疼痛の処置方法 Download PDF

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Publication number
JP6641263B2
JP6641263B2 JP2016509176A JP2016509176A JP6641263B2 JP 6641263 B2 JP6641263 B2 JP 6641263B2 JP 2016509176 A JP2016509176 A JP 2016509176A JP 2016509176 A JP2016509176 A JP 2016509176A JP 6641263 B2 JP6641263 B2 JP 6641263B2
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JP
Japan
Prior art keywords
alkyl
hydroxy
group
pain
fatty acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2016509176A
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English (en)
Japanese (ja)
Other versions
JP2016528165A5 (enExample
JP2016528165A (ja
Inventor
上野　隆司
隆司 上野
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sucampo GmbH
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Sucampo GmbH
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Publication of JP2016528165A5 publication Critical patent/JP2016528165A5/ja
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/26—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing rings other than six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/132—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen containing rings
    • C07C53/134—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen containing rings monocyclic

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2016509176A 2013-08-22 2014-08-21 神経障害性疼痛の処置方法 Expired - Fee Related JP6641263B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361868750P 2013-08-22 2013-08-22
US61/868,750 2013-08-22
US201361918124P 2013-12-19 2013-12-19
US61/918,124 2013-12-19
PCT/JP2014/072508 WO2015025980A1 (en) 2013-08-22 2014-08-21 Method for treating neuropathic pain

Publications (3)

Publication Number Publication Date
JP2016528165A JP2016528165A (ja) 2016-09-15
JP2016528165A5 JP2016528165A5 (enExample) 2017-09-28
JP6641263B2 true JP6641263B2 (ja) 2020-02-05

Family

ID=52480928

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016509176A Expired - Fee Related JP6641263B2 (ja) 2013-08-22 2014-08-21 神経障害性疼痛の処置方法

Country Status (4)

Country Link
US (1) US20150057351A1 (enExample)
EP (1) EP3035925A4 (enExample)
JP (1) JP6641263B2 (enExample)
WO (1) WO2015025980A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3352749A4 (en) 2015-09-22 2019-09-04 Graybug Vision, Inc. COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF EYE DISEASES
US20190343805A1 (en) * 2017-01-06 2019-11-14 Clexio Biosciences Ltd. Topical detomidine formulations

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5166174A (en) 1987-01-28 1992-11-24 K.K. Ueno Seiyaku Oyo Kenkyujo Prostaglandins E and anti-ulcers containing same
CA1322749C (en) 1987-01-28 1993-10-05 Ryuzo Ueno Prostaglandins of the d series, and tranquilizers and soporifics containing the same
US5221763A (en) 1987-04-30 1993-06-22 R-Tech Ueno, Ltd. Prostaglandins of the F series
TW249226B (enExample) 1990-04-04 1995-06-11 Aderk Ueno Kk
CA2150287C (en) 1994-06-03 2004-08-10 Ryuji Ueno Agent for treating hepato-biliary diseases
WO1997047595A1 (en) 1996-06-10 1997-12-18 R-Tech Ueno, Ltd. Endothelin antagonist
WO2002007822A2 (en) * 2000-07-21 2002-01-31 Ortho-Mcneil Pharmaceutical, Inc. Carbamate compounds for use in preventing or treating neuropathic pain and cluster and migraine headache-associated pain
PL365442A1 (en) * 2001-02-22 2005-01-10 Ono Pharmaceutical Co, Ltd. Medicinal compositions comprising diclofenac and ornoprostil
CA2458471C (en) * 2001-08-31 2012-07-31 Sucampo Ag Prostaglandin analogs as chloride channel opener
CA2565486A1 (en) * 2004-05-11 2005-12-08 Incyte Corporation 3-(4-heteroarylcyclohexylamino)cyclopentanecarboxamides as modulators of chemokine receptors
AR055038A1 (es) * 2005-03-04 2007-08-01 Sucampo Ag Metodo y compuesto para tratar enfermedades vasculares perifericas
US20090030072A1 (en) * 2007-07-03 2009-01-29 Sucampo Ag Pharmaceutical combination of opioid and prostaglandin compound
JP2010106019A (ja) * 2008-10-02 2010-05-13 Kanazawa Univ リマプロストを含有してなる癌化学療法に起因する末梢神経障害予防、治療および／または症状軽減剤
US20110034424A1 (en) * 2009-06-30 2011-02-10 Sucampo Ag Method for the long term nsaid use
BR112014002712A8 (pt) * 2011-08-05 2017-06-20 Sucampo Ag método para tratamento da esquizofrenia

Also Published As

Publication number Publication date
US20150057351A1 (en) 2015-02-26
EP3035925A4 (en) 2017-03-29
JP2016528165A (ja) 2016-09-15
WO2015025980A1 (en) 2015-02-26
EP3035925A1 (en) 2016-06-29

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