JP6623212B2 - 複数のモードで振動可能な超音波式手術用ツール及びツール先端部の非線形振動をもたらす駆動システム - Google Patents
複数のモードで振動可能な超音波式手術用ツール及びツール先端部の非線形振動をもたらす駆動システム Download PDFInfo
- Publication number
- JP6623212B2 JP6623212B2 JP2017506766A JP2017506766A JP6623212B2 JP 6623212 B2 JP6623212 B2 JP 6623212B2 JP 2017506766 A JP2017506766 A JP 2017506766A JP 2017506766 A JP2017506766 A JP 2017506766A JP 6623212 B2 JP6623212 B2 JP 6623212B2
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- JP
- Japan
- Prior art keywords
- drive signal
- tip
- handpiece
- vibration mode
- voltage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/32—Surgical cutting instruments
- A61B17/320068—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/32—Surgical cutting instruments
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B06—GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS IN GENERAL
- B06B—METHODS OR APPARATUS FOR GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS OF INFRASONIC, SONIC, OR ULTRASONIC FREQUENCY, e.g. FOR PERFORMING MECHANICAL WORK IN GENERAL
- B06B1/00—Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency
- B06B1/02—Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency making use of electrical energy
- B06B1/0207—Driving circuits
- B06B1/0223—Driving circuits for generating signals continuous in time
- B06B1/0269—Driving circuits for generating signals continuous in time for generating multiple frequencies
- B06B1/0276—Driving circuits for generating signals continuous in time for generating multiple frequencies with simultaneous generation, e.g. with modulation, harmonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00017—Electrical control of surgical instruments
- A61B2017/00022—Sensing or detecting at the treatment site
- A61B2017/00026—Conductivity or impedance, e.g. of tissue
- A61B2017/0003—Conductivity or impedance, e.g. of tissue of parts of the instruments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00017—Electrical control of surgical instruments
- A61B2017/00022—Sensing or detecting at the treatment site
- A61B2017/00106—Sensing or detecting at the treatment site ultrasonic
- A61B2017/0011—Sensing or detecting at the treatment site ultrasonic piezoelectric
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00017—Electrical control of surgical instruments
- A61B2017/00137—Details of operation mode
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00017—Electrical control of surgical instruments
- A61B2017/00137—Details of operation mode
- A61B2017/00141—Details of operation mode continuous, e.g. wave
- A61B2017/00146—Details of operation mode continuous, e.g. wave with multiple frequencies
- A61B2017/0015—Details of operation mode continuous, e.g. wave with multiple frequencies applied simultaneously
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00367—Details of actuation of instruments, e.g. relations between pushing buttons, or the like, and activation of the tool, working tip, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00681—Aspects not otherwise provided for
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00973—Surgical instruments, devices or methods pedal-operated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/22—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
- A61B17/22004—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
- A61B2017/22005—Effects, e.g. on tissue
- A61B2017/22007—Cavitation or pseudocavitation, i.e. creation of gas bubbles generating a secondary shock wave when collapsing
- A61B2017/22009—Cavitation or pseudocavitation, i.e. creation of gas bubbles generating a secondary shock wave when collapsing reduced or prevented
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/32—Surgical cutting instruments
- A61B17/320068—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic
- A61B2017/32007—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic with suction or vacuum means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/32—Surgical cutting instruments
- A61B17/320068—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic
- A61B2017/320072—Working tips with special features, e.g. extending parts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/32—Surgical cutting instruments
- A61B17/320068—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic
- A61B2017/320098—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic with transverse or torsional motion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2217/00—General characteristics of surgical instruments
- A61B2217/002—Auxiliary appliance
- A61B2217/007—Auxiliary appliance with irrigation system
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B06—GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS IN GENERAL
- B06B—METHODS OR APPARATUS FOR GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS OF INFRASONIC, SONIC, OR ULTRASONIC FREQUENCY, e.g. FOR PERFORMING MECHANICAL WORK IN GENERAL
- B06B1/00—Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency
- B06B1/02—Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency making use of electrical energy
- B06B1/06—Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency making use of electrical energy operating with piezoelectric effect or with electrostriction
- B06B1/0607—Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency making use of electrical energy operating with piezoelectric effect or with electrostriction using multiple elements
- B06B1/0611—Methods or apparatus for generating mechanical vibrations of infrasonic, sonic, or ultrasonic frequency making use of electrical energy operating with piezoelectric effect or with electrostriction using multiple elements in a pile
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B06—GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS IN GENERAL
- B06B—METHODS OR APPARATUS FOR GENERATING OR TRANSMITTING MECHANICAL VIBRATIONS OF INFRASONIC, SONIC, OR ULTRASONIC FREQUENCY, e.g. FOR PERFORMING MECHANICAL WORK IN GENERAL
- B06B2201/00—Indexing scheme associated with B06B1/0207 for details covered by B06B1/0207 but not provided for in any of its subgroups
- B06B2201/70—Specific application
- B06B2201/76—Medical, dental
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Mechanical Engineering (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Dentistry (AREA)
- Surgical Instruments (AREA)
- Power Engineering (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Apparatuses For Generation Of Mechanical Vibrations (AREA)
- Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462034585P | 2014-08-07 | 2014-08-07 | |
| US62/034,585 | 2014-08-07 | ||
| PCT/US2015/044023 WO2016022808A1 (en) | 2014-08-07 | 2015-08-06 | Ultrasonic surgical tool capable of vibrating in plural modes and a drive system that induces non-linear vibrations in the tool tip |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019211273A Division JP7169259B2 (ja) | 2014-08-07 | 2019-11-22 | 複数のモードで振動可能な超音波式手術用ツール及びツール先端部の非線形振動をもたらす駆動システム |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017527349A JP2017527349A (ja) | 2017-09-21 |
| JP2017527349A5 JP2017527349A5 (enExample) | 2018-09-13 |
| JP6623212B2 true JP6623212B2 (ja) | 2019-12-18 |
Family
ID=53901143
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017506766A Active JP6623212B2 (ja) | 2014-08-07 | 2015-08-06 | 複数のモードで振動可能な超音波式手術用ツール及びツール先端部の非線形振動をもたらす駆動システム |
| JP2019211273A Active JP7169259B2 (ja) | 2014-08-07 | 2019-11-22 | 複数のモードで振動可能な超音波式手術用ツール及びツール先端部の非線形振動をもたらす駆動システム |
| JP2022173126A Active JP7695923B2 (ja) | 2014-08-07 | 2022-10-28 | 複数のモードで振動可能な超音波式手術用ツール及びツール先端部の非線形振動をもたらす駆動システム |
| JP2025095658A Pending JP2025157213A (ja) | 2014-08-07 | 2025-06-09 | 複数のモードで振動可能な超音波式手術用ツール及びツール先端部の非線形振動をもたらす駆動システム |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019211273A Active JP7169259B2 (ja) | 2014-08-07 | 2019-11-22 | 複数のモードで振動可能な超音波式手術用ツール及びツール先端部の非線形振動をもたらす駆動システム |
| JP2022173126A Active JP7695923B2 (ja) | 2014-08-07 | 2022-10-28 | 複数のモードで振動可能な超音波式手術用ツール及びツール先端部の非線形振動をもたらす駆動システム |
| JP2025095658A Pending JP2025157213A (ja) | 2014-08-07 | 2025-06-09 | 複数のモードで振動可能な超音波式手術用ツール及びツール先端部の非線形振動をもたらす駆動システム |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US10561435B2 (enExample) |
| EP (2) | EP4212112B1 (enExample) |
| JP (4) | JP6623212B2 (enExample) |
| KR (3) | KR102480319B1 (enExample) |
| CN (2) | CN107106197B (enExample) |
| AU (2) | AU2015300921B2 (enExample) |
| CA (1) | CA2957281A1 (enExample) |
| WO (1) | WO2016022808A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102658766B1 (ko) | 2013-08-07 | 2024-04-18 | 스트리커 코포레이션 | 초음파 핸드피스를 이 핸드피스의 기계 임피던스의 함수로서 구동시키기 위한 시스템 및 방법 |
| AU2015300921B2 (en) | 2014-08-07 | 2020-05-07 | Stryker Corporation | Ultrasonic surgical tool capable of vibrating in plural modes and a drive system that induces non-linear vibrations in the tool tip |
| WO2017106329A1 (en) | 2015-12-18 | 2017-06-22 | Stryker Corporation | Ultrasonic surgical tool system including a tip capable of simultaneous longitudinal and torsional movement and of substantially torsional oscillations |
| EP4257066A3 (en) | 2016-05-31 | 2023-11-29 | Stryker Corporation | Control console comprising a transformer with a leakage control winding and a capacitor |
| AU2018381241B2 (en) | 2017-12-06 | 2024-11-21 | Stryker Corporation | System and methods for controlling patient leakage current in a surgical system |
| JP7637055B2 (ja) * | 2018-09-24 | 2025-02-27 | ストライカー・コーポレイション | 超音波外科用ハンドピースアセンブリ |
| US11918245B2 (en) | 2018-10-05 | 2024-03-05 | Kogent Surgical, LLC | Ultrasonic surgical handpiece with torsional transducer |
| US11871953B2 (en) | 2019-04-30 | 2024-01-16 | Stryker Corporation | Adapter and methods for coupling an ultrasonic surgical handpiece to a control console |
| JP6873494B2 (ja) * | 2019-07-26 | 2021-05-19 | ミクロン精密株式会社 | ハンドピース型高周波振動装置 |
| WO2021119616A1 (en) | 2019-12-12 | 2021-06-17 | Stryker Corporation | Control of an ultrasonic handpiece |
| DE102020112851A1 (de) * | 2020-05-12 | 2021-11-18 | Carl Zeiss Meditec Ag | Steuergerät für eine elektrische Antriebseinheit eines ophthalmochirurgischen Handstücks und Verfahren zu dessen Betrieb, ophthalmochirurgische Vorrichtung und System |
| JP7777546B2 (ja) * | 2020-06-04 | 2025-11-28 | ストライカー・コーポレイション | 組織をプローブして切除するための超音波外科用吸引器 |
| JP2023544234A (ja) * | 2020-10-01 | 2023-10-23 | ストライカー・コーポレイション | 超音波ツールシステムのためのパルス制御 |
| CA3243091A1 (en) | 2022-02-28 | 2023-08-31 | Alcon Inc | BIMODAL ULTRASONIC HANDPIECE SYSTEM |
| US12427059B2 (en) * | 2023-05-10 | 2025-09-30 | Zevex, Inc. | Ultrasonic handpiece assembly |
| WO2025038559A1 (en) * | 2023-08-12 | 2025-02-20 | Stryker Corporation | Ultrasonic surgical tool system with auxiliary power |
| WO2025081187A1 (en) | 2023-10-11 | 2025-04-17 | Stryker Corporation | Tissue sensing with an ultrasonic resection tool |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US5462522A (en) * | 1993-04-19 | 1995-10-31 | Olympus Optical Co., Ltd. | Ultrasonic therapeutic apparatus |
| JP3486469B2 (ja) | 1994-10-26 | 2004-01-13 | オリンパス株式会社 | 圧電振動子の駆動装置 |
| JP4384271B2 (ja) | 1997-11-14 | 2009-12-16 | オリンパス株式会社 | 超音波手術装置 |
| JP3286606B2 (ja) | 1998-09-03 | 2002-05-27 | 住友ベークライト株式会社 | 超音波振動子の駆動装置 |
| US6527212B2 (en) * | 1999-06-03 | 2003-03-04 | Carl A. Rupp | Ice shaver |
| US7476233B1 (en) | 2000-10-20 | 2009-01-13 | Ethicon Endo-Surgery, Inc. | Ultrasonic surgical system within digital control |
| JP2003190180A (ja) | 2001-12-27 | 2003-07-08 | Miwatec:Kk | 複合振動超音波ハンドピ−ス |
| JP4084253B2 (ja) * | 2002-11-22 | 2008-04-30 | オリンパス株式会社 | 超音波手術装置、超音波駆動装置および超音波駆動装置の制御方法 |
| JP4472395B2 (ja) | 2003-08-07 | 2010-06-02 | オリンパス株式会社 | 超音波手術システム |
| JP4129217B2 (ja) * | 2003-09-29 | 2008-08-06 | オリンパス株式会社 | 超音波手術システム、その異常検知方法および異常検知プログラム |
| US7815433B2 (en) | 2005-06-10 | 2010-10-19 | Tti Turner Technology Instruments Inc. | Adjustable tool drive arrangement |
| US20080147092A1 (en) | 2006-10-23 | 2008-06-19 | Michael Rogge | Hybrid energy instrument combined with clip application capability |
| US20080208108A1 (en) * | 2007-02-28 | 2008-08-28 | Kenichi Kimura | Treatment apparatus for operation |
| US8252012B2 (en) * | 2007-07-31 | 2012-08-28 | Ethicon Endo-Surgery, Inc. | Ultrasonic surgical instrument with modulator |
| US20100125292A1 (en) * | 2008-11-20 | 2010-05-20 | Wiener Eitan T | Ultrasonic surgical system |
| US8334635B2 (en) | 2009-06-24 | 2012-12-18 | Ethicon Endo-Surgery, Inc. | Transducer arrangements for ultrasonic surgical instruments |
| IN2012DN00339A (enExample) * | 2009-07-15 | 2015-08-21 | Ethicon Endo Surgery Inc | |
| US10441345B2 (en) | 2009-10-09 | 2019-10-15 | Ethicon Llc | Surgical generator for ultrasonic and electrosurgical devices |
| EP2672903A4 (en) * | 2011-02-10 | 2017-07-12 | Actuated Medical, Inc. | Medical tool with electromechanical control and feedback |
| WO2014012032A2 (en) * | 2012-07-13 | 2014-01-16 | Entrigue Surgical, Inc. | Low frequency ultrasound surgical systems for the treatment of soft tissues |
| KR102658766B1 (ko) | 2013-08-07 | 2024-04-18 | 스트리커 코포레이션 | 초음파 핸드피스를 이 핸드피스의 기계 임피던스의 함수로서 구동시키기 위한 시스템 및 방법 |
| GB2521228A (en) | 2013-12-16 | 2015-06-17 | Ethicon Endo Surgery Inc | Medical device |
| AU2015300921B2 (en) | 2014-08-07 | 2020-05-07 | Stryker Corporation | Ultrasonic surgical tool capable of vibrating in plural modes and a drive system that induces non-linear vibrations in the tool tip |
| US9649147B2 (en) | 2015-09-17 | 2017-05-16 | Eximis Surgical, LLC | Electrosurgical device and methods |
-
2015
- 2015-08-06 AU AU2015300921A patent/AU2015300921B2/en active Active
- 2015-08-06 EP EP23160125.3A patent/EP4212112B1/en active Active
- 2015-08-06 KR KR1020177006213A patent/KR102480319B1/ko active Active
- 2015-08-06 WO PCT/US2015/044023 patent/WO2016022808A1/en not_active Ceased
- 2015-08-06 CN CN201580053626.1A patent/CN107106197B/zh active Active
- 2015-08-06 EP EP15753550.1A patent/EP3177217B1/en active Active
- 2015-08-06 CA CA2957281A patent/CA2957281A1/en active Pending
- 2015-08-06 CN CN201910680729.0A patent/CN110251204A/zh active Pending
- 2015-08-06 KR KR1020247034891A patent/KR20240154705A/ko active Pending
- 2015-08-06 JP JP2017506766A patent/JP6623212B2/ja active Active
- 2015-08-06 KR KR1020227044446A patent/KR102721132B1/ko active Active
-
2017
- 2017-02-06 US US15/425,480 patent/US10561435B2/en active Active
-
2019
- 2019-10-07 US US16/594,671 patent/US11617598B2/en active Active
- 2019-11-22 JP JP2019211273A patent/JP7169259B2/ja active Active
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2020
- 2020-08-07 AU AU2020213394A patent/AU2020213394B2/en active Active
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2022
- 2022-10-28 JP JP2022173126A patent/JP7695923B2/ja active Active
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2023
- 2023-03-10 US US18/119,916 patent/US12419663B2/en active Active
-
2025
- 2025-01-17 US US19/028,868 patent/US20250160874A1/en active Pending
- 2025-06-09 JP JP2025095658A patent/JP2025157213A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN107106197A (zh) | 2017-08-29 |
| EP3177217B1 (en) | 2023-03-08 |
| CA2957281A1 (en) | 2016-02-11 |
| JP2025157213A (ja) | 2025-10-15 |
| EP3177217A1 (en) | 2017-06-14 |
| KR102721132B1 (ko) | 2024-10-24 |
| EP4212112A1 (en) | 2023-07-19 |
| US11617598B2 (en) | 2023-04-04 |
| US20200038053A1 (en) | 2020-02-06 |
| WO2016022808A1 (en) | 2016-02-11 |
| KR20240154705A (ko) | 2024-10-25 |
| US10561435B2 (en) | 2020-02-18 |
| JP2017527349A (ja) | 2017-09-21 |
| KR20170039726A (ko) | 2017-04-11 |
| JP7695923B2 (ja) | 2025-06-19 |
| AU2020213394B2 (en) | 2023-02-16 |
| KR20230003402A (ko) | 2023-01-05 |
| JP2020049228A (ja) | 2020-04-02 |
| JP2023029830A (ja) | 2023-03-07 |
| CN110251204A (zh) | 2019-09-20 |
| JP7169259B2 (ja) | 2022-11-10 |
| US20230210550A1 (en) | 2023-07-06 |
| AU2020213394A1 (en) | 2020-08-27 |
| AU2015300921A1 (en) | 2017-03-02 |
| US12419663B2 (en) | 2025-09-23 |
| AU2015300921B2 (en) | 2020-05-07 |
| US20170143369A1 (en) | 2017-05-25 |
| EP4212112B1 (en) | 2025-09-24 |
| KR102480319B1 (ko) | 2022-12-23 |
| CN107106197B (zh) | 2019-08-27 |
| US20250160874A1 (en) | 2025-05-22 |
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