JP6568513B2 - シリコン系担体粒子を含む薬物送達デバイス - Google Patents

シリコン系担体粒子を含む薬物送達デバイス Download PDF

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Publication number
JP6568513B2
JP6568513B2 JP2016501507A JP2016501507A JP6568513B2 JP 6568513 B2 JP6568513 B2 JP 6568513B2 JP 2016501507 A JP2016501507 A JP 2016501507A JP 2016501507 A JP2016501507 A JP 2016501507A JP 6568513 B2 JP6568513 B2 JP 6568513B2
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Prior art keywords
beneficial agent
tube
particles
silicon
shell
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Expired - Fee Related
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JP2016501507A
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Japanese (ja)
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JP2016519654A5 (enExample
JP2016519654A (ja
Inventor
キャナム，リー，ティー．
グオ，ホン
ナッツァーロ，マーティン
バーネット，クリスチャン
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Eyepoint Pharmaceuticals US Inc
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Psivida US Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B29/00—Packaging of materials presenting special problems
    • B65B29/02—Packaging of substances, e.g. tea, which are intended to be infused in the package
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts or implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B55/00—Preserving, protecting or purifying packages or package contents in association with packaging
    • B65B55/02—Sterilising, e.g. of complete packages
    • B65B55/04—Sterilising wrappers or receptacles prior to, or during, packaging
    • B65B55/06—Sterilising wrappers or receptacles prior to, or during, packaging by heat
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B55/00—Preserving, protecting or purifying packages or package contents in association with packaging
    • B65B55/02—Sterilising, e.g. of complete packages
    • B65B55/04—Sterilising wrappers or receptacles prior to, or during, packaging
    • B65B55/08—Sterilising wrappers or receptacles prior to, or during, packaging by irradiation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B7/00—Closing containers or receptacles after filling
    • B65B7/16—Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons
    • B65B7/28—Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons by applying separate preformed closures, e.g. lids, covers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Mechanical Engineering (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Nanotechnology (AREA)
  • Inorganic Chemistry (AREA)
  • Toxicology (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2016501507A 2013-03-12 2014-03-12 シリコン系担体粒子を含む薬物送達デバイス Expired - Fee Related JP6568513B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361778111P 2013-03-12 2013-03-12
US61/778,111 2013-03-12
PCT/US2014/024362 WO2014165097A1 (en) 2013-03-12 2014-03-12 Drug delivery device comprising silicon-based carrier particles

Publications (3)

Publication Number Publication Date
JP2016519654A JP2016519654A (ja) 2016-07-07
JP2016519654A5 JP2016519654A5 (enExample) 2017-04-13
JP6568513B2 true JP6568513B2 (ja) 2019-08-28

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016501507A Expired - Fee Related JP6568513B2 (ja) 2013-03-12 2014-03-12 シリコン系担体粒子を含む薬物送達デバイス

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Country Link
US (1) US20140309610A1 (enExample)
EP (1) EP2968882B1 (enExample)
JP (1) JP6568513B2 (enExample)
CN (1) CN105025974A (enExample)
AU (1) AU2014248707B2 (enExample)
CA (1) CA2904204A1 (enExample)
HK (1) HK1216864A1 (enExample)
RU (1) RU2695536C2 (enExample)
WO (1) WO2014165097A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017507165A (ja) 2013-12-16 2017-03-16 マサチューセッツ インスティテュート オブ テクノロジー マイクロモールド成形された、または３次元印刷されたパルス放出ワクチン製剤
WO2016204026A1 (ja) * 2015-06-15 2016-12-22 ｓｅｖｅｎ ｄｒｅａｍｅｒｓ ｌａｂｏｒａｔｏｒｉｅｓ株式会社 鼻腔留置デバイス
CA3066437A1 (en) * 2017-06-13 2018-12-20 EyePoint Pharmaceuticals, Inc. Bioerodible drug delivery devices
US20190076631A1 (en) * 2017-09-13 2019-03-14 Massachusetts Institute Of Technology Microdevices with complex geometries
CN109001188B (zh) * 2018-08-12 2021-09-14 河北农业大学 一种金刚烷胺和金刚乙胺的特异性分子印迹聚合物、化学发光试剂盒、检测方法及应用
CN114401716A (zh) * 2019-07-22 2022-04-26 纳诺米有限公司 持续释放的曲前列环素-化合物微粒组合物
CA3158651A1 (en) * 2019-11-27 2021-06-03 Marc M. Baum Permeable skin sustained release drug delivery device
CN112137984B (zh) * 2020-10-30 2023-02-03 四川制药制剂有限公司 头孢克洛胶囊及其制备工艺
JP7876831B2 (ja) 2021-02-26 2026-06-22 ナノ ターゲティング アンド セラピー バイオファーマ インコーポレイテッド 薬剤を後眼部に送達するための方法およびその使用
CN118059373A (zh) * 2022-11-23 2024-05-24 中国科学院深圳先进技术研究院 抑制交感神经的医疗器械及其制备方法
CN117414341B (zh) * 2023-11-15 2026-07-17 南京正科医药股份有限公司 一种盐酸达泊西汀片及其制备方法
US12390420B1 (en) 2024-10-22 2025-08-19 Bryet Us, Inc. Compositions for targeted delivery of therapeutic agents and methods for the synthesis and use thereof

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3214667C2 (de) * 1982-04-21 1985-07-18 Akzo Gmbh, 5600 Wuppertal Zusammengesetzter Körper für die Langzeitabgabe von Wirkstoffen
GB9815819D0 (en) * 1998-07-22 1998-09-16 Secr Defence Transferring materials into cells and a microneedle array
HK1040921B (en) * 1998-12-23 2005-12-30 Alza Corporation Dosage forms comprising porous particles
US6375972B1 (en) * 2000-04-26 2002-04-23 Control Delivery Systems, Inc. Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
GB0104383D0 (en) * 2001-02-22 2001-04-11 Psimedica Ltd Cancer Treatment
CA2460334A1 (en) * 2001-09-14 2003-03-27 Francis J. Martin Microfabricated nanopore device for sustained release of therapeutic agent
US20100196435A1 (en) * 2007-07-10 2010-08-05 The Regents Of The University Of California Materials and methods for delivering compositions to selected tissues
WO2010111627A1 (en) * 2009-03-26 2010-09-30 Psivida Us, Inc. Implantable formulations of bisphosphonic acids
US20110238036A1 (en) * 2009-12-23 2011-09-29 Psivida Us, Inc. Sustained release delivery devices
RU2640918C2 (ru) * 2010-11-01 2018-01-12 Псивида Юэс, Инк. Биоразлагаемые устройства на основе кремния для доставки терапевтических агентов
WO2012088306A2 (en) * 2010-12-22 2012-06-28 Psivida Us, Inc. Two-piece injectable drug delivery device with heat-cured seal
AU2012214146A1 (en) * 2011-02-11 2013-08-29 Psivida Us, Inc. Methods of treating macular edema using antiedema therapeutics
US20130053794A1 (en) * 2011-08-29 2013-02-28 Suzanne Cadden Sustained release delivery of active agents to treat glaucoma and ocular hypertension

Also Published As

Publication number Publication date
RU2695536C2 (ru) 2019-07-23
US20140309610A1 (en) 2014-10-16
EP2968882A1 (en) 2016-01-20
WO2014165097A1 (en) 2014-10-09
AU2014248707B2 (en) 2018-11-22
RU2015132216A (ru) 2017-04-18
CN105025974A (zh) 2015-11-04
EP2968882B1 (en) 2021-05-19
CA2904204A1 (en) 2014-10-09
AU2014248707A1 (en) 2015-08-20
JP2016519654A (ja) 2016-07-07
HK1216864A1 (zh) 2016-12-09
EP2968882A4 (en) 2016-08-10

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