JP6564873B2 - リポソーム組成物およびその製造方法 - Google Patents
リポソーム組成物およびその製造方法 Download PDFInfo
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- JP6564873B2 JP6564873B2 JP2017548770A JP2017548770A JP6564873B2 JP 6564873 B2 JP6564873 B2 JP 6564873B2 JP 2017548770 A JP2017548770 A JP 2017548770A JP 2017548770 A JP2017548770 A JP 2017548770A JP 6564873 B2 JP6564873 B2 JP 6564873B2
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- Prior art keywords
- liposome
- lipid
- nucleic acid
- anticancer agent
- acid analog
- Prior art date
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
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- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- Chemical & Material Sciences (AREA)
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- General Chemical & Material Sciences (AREA)
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PT3138555T (pt) | 2014-04-30 | 2020-12-15 | Fujifilm Corp | Composição lipossómica e método de produção da mesma |
EP4129304A4 (fr) | 2020-04-03 | 2023-06-07 | FUJIFILM Corporation | Agent antitumoral |
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US2566559A (en) * | 1951-09-04 | Preparation of agetals | ||
JP2931981B2 (ja) * | 1988-03-04 | 1999-08-09 | 武田薬品工業株式会社 | リポソーム製剤およびその製造法 |
US5153000A (en) * | 1988-11-22 | 1992-10-06 | Kao Corporation | Phosphate, liposome comprising the phosphate as membrane constituent, and cosmetic and liposome preparation comprising the liposome |
US5049392A (en) * | 1989-01-18 | 1991-09-17 | The Liposome Company, Inc. | Osmotically dependent vesicles |
IS1685B (is) * | 1990-12-11 | 1998-02-24 | Bracco International B.V. | Aðferð við að búa til fitukúlur (liposomes) sem eru gæddar auknum hæfileika til að draga í sig og halda í sér aðskotaefnum |
US5993850A (en) * | 1994-09-13 | 1999-11-30 | Skyepharma Inc. | Preparation of multivesicular liposomes for controlled release of encapsulated biologically active substances |
EP0825852B1 (fr) * | 1995-04-18 | 2004-07-07 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Procede de chargement de medicaments dans des liposomes et composition |
DE19813773A1 (de) | 1998-03-27 | 1999-09-30 | Clemens Unger | Verfahren zur Herstellung von liposomalen Wirkstoffformulierungen |
US6726925B1 (en) * | 1998-06-18 | 2004-04-27 | Duke University | Temperature-sensitive liposomal formulation |
JP2000302685A (ja) * | 1999-02-18 | 2000-10-31 | Sankyo Co Ltd | 抗腫瘍薬含有リポソーム製剤 |
US6727475B2 (en) * | 2001-07-27 | 2004-04-27 | Eastman Kodak Company | Heating control system which minimizes AC power line voltage fluctuations |
WO2003083443A2 (fr) * | 2002-03-29 | 2003-10-09 | University Of Florida | Criblage a base de lipides de medicaments candidats, destine a l'identification de composes actifs |
CA2536612A1 (fr) * | 2003-04-02 | 2004-10-14 | Celator Pharmaceuticals, Inc. | Compositions combinees de camptothecines et de fluoropyrimidines |
WO2005021012A1 (fr) * | 2003-08-29 | 2005-03-10 | Terumo Kabushiki Kaisha | Vecteur de medicament contenant de la gemcitabine |
AU2005235455B2 (en) * | 2004-04-22 | 2011-01-20 | Celator Pharmaceuticals, Inc. | Liposomal formulations of anthracycline agents and cytidine analogs |
CN107811971B (zh) * | 2004-05-03 | 2021-10-29 | 益普生生物制药公司 | 用于药物输送的脂质体 |
JP4758915B2 (ja) * | 2004-08-06 | 2011-08-31 | バイオスペクトラム,インコーポレイテッド | 多重層リポソームおよびその製造方法 |
US20080213183A1 (en) * | 2004-09-20 | 2008-09-04 | Marcel Bally | Free or Liposomal Gemcitabine Alone or in Combination with Free or Liposomal Idarubicin |
JP5110880B2 (ja) * | 2004-11-18 | 2012-12-26 | テルモ株式会社 | 医薬組成物、製剤および組み合わせ製剤 |
EP1674081A1 (fr) * | 2004-12-23 | 2006-06-28 | KTB Tumorforschungsgesellschaft mbH | Préparation de nano-particules à bases lipides en utilisant une centrifuge duale et asymétrique |
GB2464430B8 (en) * | 2007-07-20 | 2011-12-21 | Rohto Pharma | Emulsified composition |
WO2009059449A1 (fr) * | 2007-11-05 | 2009-05-14 | Celsion Corporation | Nouveaux liposomes thermosensibles contenant des agents thérapeutiques |
US8079820B2 (en) * | 2008-12-18 | 2011-12-20 | General Electric Company | Blade module, a modular rotor blade and a method for assembling a modular rotor blade |
CA2756811C (fr) * | 2009-03-30 | 2014-09-23 | Eisai R&D Management Co., Ltd. | Composition liposomique d'eribuline ou un sel pharmacologiquement accepttable de celui-ci |
US8215869B2 (en) * | 2009-07-27 | 2012-07-10 | Terratech Consulting Ltd. | Reinforced soil arch |
CA2794473A1 (fr) * | 2010-02-03 | 2011-08-11 | National Cancer Center | Cellule souche hepatique induite et procede pour la production de celle-ci, et applications de la cellule |
PL226015B1 (pl) * | 2011-03-03 | 2017-06-30 | Wrocławskie Centrum Badań Eit + Spółka Z Ograniczoną | Liposomowy preparat zawierajacy przeciwnowotworowa substancje aktywna, sposob jego wytwarzania i zawierajaca go kompozycja farmaceutyczna |
CN106727329B (zh) * | 2012-02-17 | 2020-11-03 | 效思因公司 | 热敏纳米颗粒制剂及其制备方法 |
US20140029493A1 (en) * | 2012-07-26 | 2014-01-30 | Sierra Wireless, Inc. | Wireless Communication Interworking Function |
KR20140120218A (ko) * | 2013-04-02 | 2014-10-13 | 삼성전자주식회사 | 혈관신생 유도 물질 전달용 조성물, 및 이를 이용하여 제작된 인공 조직 |
PT3138555T (pt) * | 2014-04-30 | 2020-12-15 | Fujifilm Corp | Composição lipossómica e método de produção da mesma |
EP3138556B1 (fr) * | 2014-04-30 | 2022-03-02 | FUJIFILM Corporation | Procédé de production de liposomes |
JP6276847B2 (ja) * | 2014-04-30 | 2018-02-07 | 富士フイルム株式会社 | リポソーム組成物及びその製造方法 |
EP3138557B1 (fr) * | 2014-04-30 | 2023-06-07 | FUJIFILM Corporation | Composition liposomale et procédé de production associé |
JP6316182B2 (ja) * | 2014-12-19 | 2018-04-25 | 富士フイルム株式会社 | リポソームの製造方法及びリポソーム製造装置 |
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JPWO2017078009A1 (ja) | 2018-08-09 |
EP3372223A1 (fr) | 2018-09-12 |
MA43184A (fr) | 2021-04-14 |
WO2017078009A1 (fr) | 2017-05-11 |
US20210128471A1 (en) | 2021-05-06 |
JP6705933B2 (ja) | 2020-06-03 |
JP2019178181A (ja) | 2019-10-17 |
US20180243215A1 (en) | 2018-08-30 |
EP3372223B1 (fr) | 2024-04-17 |
EP3372223A4 (fr) | 2018-09-12 |
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