JP6518251B2 - 経脊髄直流調整システム - Google Patents
経脊髄直流調整システム Download PDFInfo
- Publication number
- JP6518251B2 JP6518251B2 JP2016534630A JP2016534630A JP6518251B2 JP 6518251 B2 JP6518251 B2 JP 6518251B2 JP 2016534630 A JP2016534630 A JP 2016534630A JP 2016534630 A JP2016534630 A JP 2016534630A JP 6518251 B2 JP6518251 B2 JP 6518251B2
- Authority
- JP
- Japan
- Prior art keywords
- stimulation
- nerve
- electrode
- spinal
- spinal cord
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/20—Applying electric currents by contact electrodes continuous direct currents
- A61N1/205—Applying electric currents by contact electrodes continuous direct currents for promoting a biological process
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0456—Specially adapted for transcutaneous electrical nerve stimulation [TENS]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0551—Spinal or peripheral nerve electrodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/08—Arrangements or circuits for monitoring, protecting, controlling or indicating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/20—Applying electric currents by contact electrodes continuous direct currents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36003—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of motor muscles, e.g. for walking assistance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/3603—Control systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
- A61N1/36062—Spinal stimulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36128—Control systems
- A61N1/36146—Control systems specified by the stimulation parameters
- A61N1/3615—Intensity
- A61N1/36157—Current
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36128—Control systems
- A61N1/36146—Control systems specified by the stimulation parameters
- A61N1/3615—Intensity
- A61N1/3616—Voltage density or current density
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Biophysics (AREA)
- Electrotherapy Devices (AREA)
- Magnetic Treatment Devices (AREA)
- Steroid Compounds (AREA)
- Gastroenterology & Hepatology (AREA)
- Amplifiers (AREA)
- Amplitude Modulation (AREA)
- Stabilization Of Oscillater, Synchronisation, Frequency Synthesizers (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361919806P | 2013-12-22 | 2013-12-22 | |
| US61/919,806 | 2013-12-22 | ||
| US201461925423P | 2014-01-09 | 2014-01-09 | |
| US61/925,423 | 2014-01-09 | ||
| US201462092214P | 2014-12-15 | 2014-12-15 | |
| US62/092,214 | 2014-12-15 | ||
| PCT/US2014/071959 WO2015095880A2 (en) | 2013-12-22 | 2014-12-22 | Trans-spinal direct current modulation systems |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017503537A JP2017503537A (ja) | 2017-02-02 |
| JP2017503537A5 JP2017503537A5 (https=) | 2018-02-08 |
| JP6518251B2 true JP6518251B2 (ja) | 2019-05-22 |
Family
ID=53403908
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016534630A Active JP6518251B2 (ja) | 2013-12-22 | 2014-12-22 | 経脊髄直流調整システム |
Country Status (20)
| Country | Link |
|---|---|
| US (3) | US9283391B2 (https=) |
| EP (2) | EP3082947B1 (https=) |
| JP (1) | JP6518251B2 (https=) |
| KR (2) | KR20160105822A (https=) |
| CN (2) | CN106029164B (https=) |
| AU (1) | AU2014368874B2 (https=) |
| CA (1) | CA2932000C (https=) |
| CY (1) | CY1122116T1 (https=) |
| DK (1) | DK3082947T3 (https=) |
| ES (2) | ES2732734T3 (https=) |
| HR (1) | HRP20191032T1 (https=) |
| HU (1) | HUE045175T2 (https=) |
| IL (1) | IL246430B (https=) |
| LT (1) | LT3082947T (https=) |
| MX (1) | MX366919B (https=) |
| PL (1) | PL3082947T3 (https=) |
| PT (1) | PT3082947T (https=) |
| SG (1) | SG11201604288WA (https=) |
| SI (1) | SI3082947T1 (https=) |
| WO (1) | WO2015095880A2 (https=) |
Families Citing this family (101)
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|---|---|---|---|---|
| US9211410B2 (en) | 2009-05-01 | 2015-12-15 | Setpoint Medical Corporation | Extremely low duty-cycle activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation |
| WO2014169145A1 (en) | 2013-04-10 | 2014-10-16 | Setpoint Medical Corporation | Closed-loop vagus nerve stimulation |
| US12172017B2 (en) | 2011-05-09 | 2024-12-24 | Setpoint Medical Corporation | Vagus nerve stimulation to treat neurodegenerative disorders |
| US9415218B2 (en) | 2011-11-11 | 2016-08-16 | The Regents Of The University Of California | Transcutaneous spinal cord stimulation: noninvasive tool for activation of locomotor circuitry |
| WO2013134543A1 (en) | 2012-03-08 | 2013-09-12 | Medtronic Ardian Luxembourg Sarl | Immune system neuromodulation and associated systems and methods |
| US10195434B2 (en) | 2012-06-15 | 2019-02-05 | Case Western Reserve University | Treatment of pain using electrical nerve conduction block |
| JP6426085B2 (ja) | 2012-06-15 | 2018-11-21 | ケース ウェスタン リザーブ ユニバーシティCase Western Reserve University | 損傷のない神経組織伝導ブロック用の治療送達装置および方法 |
| US12453853B2 (en) | 2013-01-21 | 2025-10-28 | Cala Health, Inc. | Multi-modal stimulation for treating tremor |
| EP3498332B1 (en) | 2013-01-21 | 2021-07-14 | Cala Health, Inc. | Devices for controlling tremor |
| AU2014228794B2 (en) | 2013-03-15 | 2019-04-18 | The Regents Of The University Of California | Multi-site transcutaneous electrical stimulation of the spinal cord for facilitation of locomotion |
| US20150238764A1 (en) | 2013-05-10 | 2015-08-27 | Case Western Reserve University | Systems and methods for preventing noise in an electric waveform for neural stimulation, block, or sensing |
| WO2014194200A1 (en) | 2013-05-30 | 2014-12-04 | Creasey Graham H | Topical neurological stimulation |
| US11229789B2 (en) | 2013-05-30 | 2022-01-25 | Neurostim Oab, Inc. | Neuro activator with controller |
| CA2924817C (en) | 2013-09-16 | 2023-09-19 | The Board Of Trustees Of The Leland Stanford Junior University | Multi-element coupler for generation of electromagnetic energy |
| US10137299B2 (en) | 2013-09-27 | 2018-11-27 | The Regents Of The University Of California | Engaging the cervical spinal cord circuitry to re-enable volitional control of hand function in tetraplegic subjects |
| US9707390B2 (en) * | 2013-12-22 | 2017-07-18 | The Research Foundation Of The City University Of New York | Apparatus for modulation of effector organs |
| US9707391B2 (en) * | 2013-12-22 | 2017-07-18 | The Research Foundation Of The City University Of New York | Method for modulation of effector organs |
| LT3082947T (lt) * | 2013-12-22 | 2019-07-10 | Research Foundation Of The City University Of New York | Transspinalinės nuolatinės srovės moduliavimo sistemos |
| US20160336813A1 (en) | 2015-05-15 | 2016-11-17 | NeuSpera Medical Inc. | Midfield coupler |
| WO2015179225A1 (en) | 2014-05-18 | 2015-11-26 | Yeh Alexander Jueshyan | Midfield coupler |
| EP3145581B1 (de) * | 2014-05-23 | 2019-07-03 | Albrecht Molsberger | Therapeutisch anwendbare mehrkanal- gleichstromabgabevorrichtung |
| AU2015271774B2 (en) | 2014-06-02 | 2020-04-16 | Cala Health, Inc. | Systems and methods for peripheral nerve stimulation to treat tremor |
| AU2015305237B2 (en) | 2014-08-21 | 2020-06-18 | The Regents Of The University Of California | Regulation of autonomic control of bladder voiding after a complete spinal cord injury |
| EP3185946B1 (en) | 2014-08-27 | 2019-10-09 | The Regents Of The University Of California | Multi-electrode array for spinal cord epidural stimulation |
| US11311725B2 (en) | 2014-10-24 | 2022-04-26 | Setpoint Medical Corporation | Systems and methods for stimulating and/or monitoring loci in the brain to treat inflammation and to enhance vagus nerve stimulation |
| JP2017536187A (ja) | 2014-12-03 | 2017-12-07 | メタベンション インコーポレイテッド | 神経または他の組織を調節するためのシステムおよび方法 |
| US11077301B2 (en) | 2015-02-21 | 2021-08-03 | NeurostimOAB, Inc. | Topical nerve stimulator and sensor for bladder control |
| CN119565022A (zh) | 2015-06-10 | 2025-03-07 | 卡拉健康公司 | 用于外周神经刺激以利用可拆卸治疗和监测单元治疗震颤的系统和方法 |
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| BR112018002218A2 (pt) * | 2015-08-03 | 2018-09-04 | Univ Duke | aparelho para modular a atividade neural de fibras aferentes, método para tratamento de disfunção da bexiga, forma de onda elétrica neuromodulatória, uso de um aparelho de neuromodulação, composição farmacêutica, e, sistema de neuromodulação |
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