HRP20191032T1 - Trans-spinalni modulacijski sustavi istosmjerne struje - Google Patents
Trans-spinalni modulacijski sustavi istosmjerne struje Download PDFInfo
- Publication number
- HRP20191032T1 HRP20191032T1 HRP20191032TT HRP20191032T HRP20191032T1 HR P20191032 T1 HRP20191032 T1 HR P20191032T1 HR P20191032T T HRP20191032T T HR P20191032TT HR P20191032 T HRP20191032 T HR P20191032T HR P20191032 T1 HRP20191032 T1 HR P20191032T1
- Authority
- HR
- Croatia
- Prior art keywords
- stimulation
- component
- current
- electrical source
- direct current
- Prior art date
Links
- 230000000638 stimulation Effects 0.000 claims 22
- 239000012636 effector Substances 0.000 claims 5
- 210000005036 nerve Anatomy 0.000 claims 5
- 210000000056 organ Anatomy 0.000 claims 5
- 210000003205 muscle Anatomy 0.000 claims 3
- 230000000541 pulsatile effect Effects 0.000 claims 2
- 210000000278 spinal cord Anatomy 0.000 claims 1
- 210000005250 spinal neuron Anatomy 0.000 claims 1
- 230000004936 stimulating effect Effects 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/20—Applying electric currents by contact electrodes continuous direct currents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0456—Specially adapted for transcutaneous electrical nerve stimulation [TENS]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0551—Spinal or peripheral nerve electrodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/08—Arrangements or circuits for monitoring, protecting, controlling or indicating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/20—Applying electric currents by contact electrodes continuous direct currents
- A61N1/205—Applying electric currents by contact electrodes continuous direct currents for promoting a biological process
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36003—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of motor muscles, e.g. for walking assistance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/3603—Control systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
- A61N1/36062—Spinal stimulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36128—Control systems
- A61N1/36146—Control systems specified by the stimulation parameters
- A61N1/3615—Intensity
- A61N1/36157—Current
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36128—Control systems
- A61N1/36146—Control systems specified by the stimulation parameters
- A61N1/3615—Intensity
- A61N1/3616—Voltage density or current density
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Biophysics (AREA)
- Electrotherapy Devices (AREA)
- Magnetic Treatment Devices (AREA)
- Amplifiers (AREA)
- Amplitude Modulation (AREA)
- Stabilization Of Oscillater, Synchronisation, Frequency Synthesizers (AREA)
- Gastroenterology & Hepatology (AREA)
- Steroid Compounds (AREA)
Claims (15)
1. Sustav za modulaciju spinalnih neurona povezan s regulacijom djelovanja efektorskih organa u tijelu kralješnjaka, sustav obuhvaća:
prvu stimulacijsku komponentu konfiguriranu na način da omogućava stimulaciju živca povezanog s ciljnim efektorskim organom; pri čemu je prva stimulacijska komponenta konfigurirana na način da pruža električnu stimulaciju istosmjernom strujom; te
drugu stimulacijsku komponentu konfiguriranu na način da omogućava stimulaciju istosmjernom strujom povezanu s modulacijom navedenog ciljanog efektorskog organa; pri čemu je druga stimulacijska komponenta konfigurirana na način da pruža spinalnu kontinuiranu stimulaciju konstantnom istosmjernom strujom; i
kontrolnu komponentu konfiguriranu na način da simultano kontrolira doseg struje koju dovode prva i druga stimulacijska komponenta i uspostavlja gornju granicu struje prve komponente ne višu od struje na drugoj stimulacijskoj komponenti.
2. Sustav sukladno zahtjevu 1 pri čemu je prva stimulacijska komponenta konfigurirana na način da omogućava:
(a) kontinuiranu stimulaciju konstantnom električnom strujom; ili
(b) pulsirajuću električnu stimulaciju.
3. Sustav sukladno zahtjevu 1 nadalje obuhvaća kontrolnu komponentu konfiguriranu na način da simultano kontrolira opseg struje koja se pruža pomoću prve i druge stimulacijske komponente i uspostavlja gornju granicu struje prve komponente ne višu od struje na drugoj stimulacijskoj komponenti i dinamički prilagođava gornju granicu simultano s prilagođavanjem druge struje.
4. Sustav sukladno zahtjevu 1 nadalje obuhvaća prvu komponentu struje konfiguriranu da pruža kontinuiranu konstantnu istosmjernu struju za stimulaciju živca povezanog s ciljnim efektorskim organom.
5. Sustav sukladno zahtjevu 1 nadalje obuhvaća prvi električni izvor s pozitivnim i negativnim terminalima koji omogućuju stimulacijsku struju na stimulacijske elektrode, uključujući dvije elektrode za stimulaciju živca povezanog s ciljnim efektorskim organom; jedna elektroda operativno je povezana s pozitivnim terminalom i druga elektroda operativno povezana s negativnim terminalom; svaka od dvije elektrode električno je izolirana od druge elektrode.
6. Sustav sukladno zahtjevu 5 pri čemu su dvije elektrode konfigurirane na način da budu pričvršćene za dio živca povezan s ciljnim mišićem radi omogućavanja kontinuirane električne stimulacije konstantnom istosmjernom strujom na dio živca mišića.
7. Sustav sukladno zahtjevu 6 nadalje obuhvaća
drugi električni izvor koji ima drugi pozitivni terminal i drugi negativni terminal;
prvu elektrodu smještenu na mjesto leđne moždine; i
drugu elektrodu koja se nalazi na drugom odabranom mjestu na spinalnoj kolumni ili mjestu distalno od kralježnice; jedna od prve ili druge elektrode operativno je spojena na drugi pozitivni terminal i druga od prve ili druge elektrode operativno je spojena na drugi negativni terminal.
8. Sustav sukladno zahtjevu 7 pri čemu su prvi električni izvor i drugi električni izvor isti električni izvor; te pri čemu je isti električni izvor onaj izvor koji proizvodi konstantnu istosmjernu struju.
9. Sustav sukladno zahtjevu 1 pri čemu je navedena istosmjerna struja za spinalnu stimulaciju opsega od otprilke 2 ma do otprilike 5mA za terapiju mišićnog tonusa kod ljudi.
10. Sustav sukladno zahtjevu 9 pri čemu su dvije elektrode usađene.
11. Sustav sukladno zahtjevu 1 pri čemu je prvi električni izvor također usađen; i pri čemu je kontrolna komponenta operativno povezana s prvim električnim izvorom pomoću bežične veze.
12. Sustav sukladno zahtjevu 11 pri čemu je kontrolna komponenta smještena u nosivom kućištu.
13. Sustav sukladno zahtjevu 12 pri čemu je drugi električni izvor također smješten u nosivom kućištu.
14. Sustav sukladno zahtjevu 13 pri čemu su kontrolna komponenta i isti električni izvor smješteni u nosivom kućištu.
15. Sustav sukladno zahtjevu 1 pri čemu je prva stimulacijska komponenta konfigurirana na način da omogući pulsirajuću električnu stimulaciju.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361919806P | 2013-12-22 | 2013-12-22 | |
| US201461925423P | 2014-01-09 | 2014-01-09 | |
| US201462092214P | 2014-12-15 | 2014-12-15 | |
| PCT/US2014/071959 WO2015095880A2 (en) | 2013-12-22 | 2014-12-22 | Trans-spinal direct current modulation systems |
| EP14872635.9A EP3082947B1 (en) | 2013-12-22 | 2014-12-22 | Trans-spinal direct current modulation systems |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20191032T1 true HRP20191032T1 (hr) | 2019-08-23 |
Family
ID=53403908
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20191032TT HRP20191032T1 (hr) | 2013-12-22 | 2019-06-07 | Trans-spinalni modulacijski sustavi istosmjerne struje |
Country Status (20)
| Country | Link |
|---|---|
| US (3) | US9283391B2 (hr) |
| EP (2) | EP3082947B1 (hr) |
| JP (1) | JP6518251B2 (hr) |
| KR (2) | KR20160105822A (hr) |
| CN (2) | CN109432596B (hr) |
| AU (1) | AU2014368874B2 (hr) |
| CA (1) | CA2932000C (hr) |
| CY (1) | CY1122116T1 (hr) |
| DK (1) | DK3082947T3 (hr) |
| ES (2) | ES2732734T3 (hr) |
| HR (1) | HRP20191032T1 (hr) |
| HU (1) | HUE045175T2 (hr) |
| IL (1) | IL246430B (hr) |
| LT (1) | LT3082947T (hr) |
| MX (1) | MX366919B (hr) |
| PL (1) | PL3082947T3 (hr) |
| PT (1) | PT3082947T (hr) |
| SG (1) | SG11201604288WA (hr) |
| SI (1) | SI3082947T1 (hr) |
| WO (1) | WO2015095880A2 (hr) |
Families Citing this family (72)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014169145A1 (en) | 2013-04-10 | 2014-10-16 | Setpoint Medical Corporation | Closed-loop vagus nerve stimulation |
| US9415218B2 (en) | 2011-11-11 | 2016-08-16 | The Regents Of The University Of California | Transcutaneous spinal cord stimulation: noninvasive tool for activation of locomotor circuitry |
| US10195434B2 (en) | 2012-06-15 | 2019-02-05 | Case Western Reserve University | Treatment of pain using electrical nerve conduction block |
| EP2861296A1 (en) | 2012-06-15 | 2015-04-22 | Case Western Reserve University | Therapy delivery devices and methods for non-damaging neural tissue conduction block |
| ES2720802T3 (es) | 2013-01-21 | 2019-07-24 | Cala Health Inc | Dispositivos para controlar temblores |
| CA2906779C (en) | 2013-03-15 | 2022-08-30 | The Regents Of The University Of California | Multi-site transcutaneous electrical stimulation of the spinal cord for facilitation of locomotion |
| US20150238764A1 (en) | 2013-05-10 | 2015-08-27 | Case Western Reserve University | Systems and methods for preventing noise in an electric waveform for neural stimulation, block, or sensing |
| EP3003473B1 (en) | 2013-05-30 | 2018-08-22 | Graham H. Creasey | Topical neurological stimulation |
| US11229789B2 (en) | 2013-05-30 | 2022-01-25 | Neurostim Oab, Inc. | Neuro activator with controller |
| AU2014318413B2 (en) | 2013-09-16 | 2019-07-11 | The Board Of Trustees Of The Leland Stanford Junior University | Multi-element coupler for generation of electromagnetic energy |
| AU2014324660A1 (en) | 2013-09-27 | 2016-04-21 | The Regents Of The University Of California | Engaging the cervical spinal cord circuitry to re-enable volitional control of hand function in tetraplegic subjects |
| US9707391B2 (en) * | 2013-12-22 | 2017-07-18 | The Research Foundation Of The City University Of New York | Method for modulation of effector organs |
| US9707390B2 (en) * | 2013-12-22 | 2017-07-18 | The Research Foundation Of The City University Of New York | Apparatus for modulation of effector organs |
| EP3082947B1 (en) * | 2013-12-22 | 2019-03-13 | Research Foundation Of The City University Of New York | Trans-spinal direct current modulation systems |
| WO2015179225A1 (en) | 2014-05-18 | 2015-11-26 | Yeh Alexander Jueshyan | Midfield coupler |
| US20160336813A1 (en) | 2015-05-15 | 2016-11-17 | NeuSpera Medical Inc. | Midfield coupler |
| JP2017516608A (ja) * | 2014-05-23 | 2017-06-22 | アルブレヒト モルスベアガーＡｌｂｒｅｃｈｔ Ｍｏｌｓｂｅｒｇｅｒ | 治療適用可能なマルチチャネル直流出力装置 |
| JP6606105B2 (ja) | 2014-06-02 | 2019-11-13 | カラ ヘルス，インコーポレイテッド | 振戦を治療するための抹消神経刺激用のシステム及び方法 |
| US10751533B2 (en) | 2014-08-21 | 2020-08-25 | The Regents Of The University Of California | Regulation of autonomic control of bladder voiding after a complete spinal cord injury |
| AU2015308779B2 (en) | 2014-08-27 | 2020-06-25 | The Regents Of The University Of California | Multi-electrode array for spinal cord epidural stimulation |
| US11077301B2 (en) | 2015-02-21 | 2021-08-03 | NeurostimOAB, Inc. | Topical nerve stimulator and sensor for bladder control |
| CA2988586A1 (en) | 2015-06-10 | 2016-12-15 | Cala Health, Inc. | Neuromodulation system for peripheral nerve stimulation with detachable therapy unit |
| RU2018103082A (ru) * | 2015-08-03 | 2019-09-05 | Гальвани Биоэлектроникс Лимитед | Нейромодуляционное устройство |
| WO2017031306A1 (en) * | 2015-08-19 | 2017-02-23 | University Of Louisville Research Foundation, Inc. | Methods for providing optimized neurostimulation |
| US11298533B2 (en) | 2015-08-26 | 2022-04-12 | The Regents Of The University Of California | Concerted use of noninvasive neuromodulation device with exoskeleton to enable voluntary movement and greater muscle activation when stepping in a chronically paralyzed subject |
| US20180243555A1 (en) * | 2015-09-08 | 2018-08-30 | Case Western Reserve Univesity | Systems and methods for transcutaneous direct current block to alter nerve conduction |
| EP3352843B1 (en) | 2015-09-23 | 2021-06-23 | Cala Health, Inc. | Device for peripheral nerve stimulation in the finger to treat hand tremors |
| US10828485B2 (en) | 2015-10-06 | 2020-11-10 | Case Western Reserve University | High-charge capacity electrodes to deliver direct current nerve conduction block |
| US11097122B2 (en) | 2015-11-04 | 2021-08-24 | The Regents Of The University Of California | Magnetic stimulation of the spinal cord to restore control of bladder and/or bowel |
| US10864373B2 (en) | 2015-12-15 | 2020-12-15 | Case Western Reserve University | Systems for treatment of a neurological disorder using electrical nerve conduction block |
| US11471681B2 (en) | 2016-01-20 | 2022-10-18 | Setpoint Medical Corporation | Batteryless implantable microstimulators |
| EP3405251A4 (en) | 2016-01-21 | 2019-08-28 | Cala Health, Inc. | SYSTEMS, METHODS AND DEVICES FOR PERIPHERAL NEUROMODULATION FOR THE TREATMENT OF DISEASES RELATED TO BUBBLE HYPERACTIVITY |
| EP3481492B1 (en) | 2016-07-08 | 2024-03-13 | Cala Health, Inc. | Systems for stimulating n nerves with exactly n electrodes and improved dry electrodes |
| AU2017251817A1 (en) * | 2016-11-04 | 2018-05-24 | Gimer Medical. Co. Ltd. | Method for reducing overactive bladder syndrome and computer-readable medium thereof |
| AU2017254920B2 (en) * | 2016-11-10 | 2019-04-04 | Gimer Medical Co. Ltd. | Method of reducing renal hypertension and computer-readable medium |
| EP4233999A3 (en) | 2016-12-12 | 2023-11-22 | The Regents of The University of California | Implantable and non-invasive stimulators for gastrointestinal therapeutics |
| ES2922929T3 (es) * | 2016-12-20 | 2022-09-21 | Galvani Bioelectronics Ltd | Dispositivo de neuromodulación |
| WO2018129351A1 (en) * | 2017-01-05 | 2018-07-12 | Shriram Raghunathan | Restless leg syndrome or overactive nerve treatment |
| WO2021067751A1 (en) | 2019-10-03 | 2021-04-08 | Noctrix Health, Inc. | Peripheral nerve stimulation for restless legs syndrome |
| EP3606599A4 (en) | 2017-04-03 | 2021-01-13 | Presidio Medical, Inc. | SYSTEMS AND PROCEDURES FOR A DC NERVOUS GUIDE BLOCK |
| WO2018187241A1 (en) | 2017-04-03 | 2018-10-11 | Cala Health, Inc. | Systems, methods and devices for peripheral neuromodulation for treating diseases related to overactive bladder |
| EP3421081B1 (en) | 2017-06-30 | 2020-04-15 | GTX medical B.V. | A system for neuromodulation |
| WO2019036470A1 (en) | 2017-08-14 | 2019-02-21 | Setpoint Medical Corporation | TESTING TEST FOR STIMULATION OF NERVE WAVE |
| KR102562469B1 (ko) | 2017-11-07 | 2023-08-01 | 뉴로스팀 오에이비, 인크. | 적응형 회로를 구비한 비침습성 신경 활성화기 |
| US11992684B2 (en) | 2017-12-05 | 2024-05-28 | Ecole Polytechnique Federale De Lausanne (Epfl) | System for planning and/or providing neuromodulation |
| CN109999341A (zh) * | 2018-01-04 | 2019-07-12 | 精能医学股份有限公司 | 电刺激器、制造电刺激器的方法及电刺激系统 |
| CN110013605A (zh) * | 2018-01-10 | 2019-07-16 | 精能医学股份有限公司 | 电刺激器、治疗方法及电刺激系统 |
| WO2019143790A1 (en) | 2018-01-17 | 2019-07-25 | Cala Health, Inc. | Systems and methods for treating inflammatory bowel disease through peripheral nerve stimulation |
| WO2019164952A1 (en) | 2018-02-20 | 2019-08-29 | Presidio Medical, Inc. | Methods and systems for nerve conduction block |
| KR102141550B1 (ko) | 2018-03-14 | 2020-08-05 | 이화여자대학교 산학협력단 | 비침습적 방광 배뇨 관리 시스템 |
| WO2019183536A1 (en) | 2018-03-22 | 2019-09-26 | Research Foundation Of The City University Of New York | Modulation of neuronal nkcc1 as a therapeutic strategy for spasticity and related disorders |
| WO2019222619A1 (en) * | 2018-05-17 | 2019-11-21 | Boston Scientific Scimed, Inc. | System for controlling blood pressure |
| EP3813925A4 (en) | 2018-07-01 | 2022-04-13 | Presidio Medical, Inc. | SYSTEMS AND METHODS FOR NERVE BLOCK |
| WO2020014336A1 (en) | 2018-07-11 | 2020-01-16 | Dignify Therapeutics, Llc | Method of treating voiding dysfunction |
| CA3110189A1 (en) * | 2018-08-21 | 2020-02-27 | The Regents Of The University Of California | Transcutaneous electrical and/or magnetic spinal stimulation for bladder or bowel control in subjects without cns injury |
| US11141587B2 (en) | 2018-08-31 | 2021-10-12 | Avation Medical, Inc. | System, method, and apparatus for applying transcutaneous electrical stimulation |
| CN109173056B (zh) * | 2018-10-19 | 2022-03-22 | 南通大学 | 一种大鼠脊髓神经信号检测与评估系统及方法 |
| US11602633B2 (en) * | 2018-10-22 | 2023-03-14 | Pathmaker Neurosystems Inc. | Method and apparatus for controlling multi-site neurostimulation |
| DE18205821T1 (de) | 2018-11-13 | 2020-12-24 | Gtx Medical B.V. | Steuerungssystem zur bewegungsrekonstruktion und/oder wiederherstellung für einen patienten |
| EP3695878B1 (en) | 2019-02-12 | 2023-04-19 | ONWARD Medical N.V. | A system for neuromodulation |
| US11617884B2 (en) | 2019-03-15 | 2023-04-04 | Case Western Reserve University | Electrically anesthetizing a peripheral nerve with on-demand electrical nerve block for chronic pain management |
| WO2020254796A1 (en) * | 2019-06-19 | 2020-12-24 | Galvani Bioelectronics Limited | Neuromodulation device |
| CN114126704A (zh) | 2019-06-26 | 2022-03-01 | 神经科学技术有限责任公司 | 具有自适应电路的非侵入性神经激活器 |
| US11890468B1 (en) | 2019-10-03 | 2024-02-06 | Cala Health, Inc. | Neurostimulation systems with event pattern detection and classification |
| CN110585597B (zh) * | 2019-10-21 | 2024-04-16 | 中南大学湘雅三医院 | 肠道蠕动智能调节系统 |
| JP2023502505A (ja) | 2019-11-24 | 2023-01-24 | プレシディオ・メディカル・インコーポレイテッド | パルス発生および刺激エンジンシステム |
| DE19211698T1 (de) | 2019-11-27 | 2021-09-02 | Onward Medical B.V. | Neuromodulation system |
| US11730958B2 (en) | 2019-12-16 | 2023-08-22 | Neurostim Solutions, Llc | Non-invasive nerve activator with boosted charge delivery |
| EP3915470A1 (en) * | 2020-05-26 | 2021-12-01 | ONWARD Medical B.V. | Neuromodulation and/or neurostimulation system |
| US20210393958A1 (en) * | 2020-05-26 | 2021-12-23 | Research Foundation Of The City University Of New York | Multi-site neuromodulation for treatment of als and related disorders |
| KR102554540B1 (ko) * | 2020-07-30 | 2023-07-12 | 재단법인대구경북과학기술원 | 맞춤형 전기 자극 제공 시스템 및 그 방법 |
| WO2023141609A2 (en) * | 2022-01-20 | 2023-07-27 | Setpoint Medical Corporation | Treatment of inflammatory disorders |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5193539A (en) | 1991-12-18 | 1993-03-16 | Alfred E. Mann Foundation For Scientific Research | Implantable microstimulator |
| US20060122660A1 (en) * | 1998-10-26 | 2006-06-08 | Boveja Birinder R | Method and system for modulating sacral nerves and/or its branches in a patient to provide therapy for urological disorders and/or fecal incontinence, using rectangular and/or complex electrical pulses |
| US6366814B1 (en) * | 1998-10-26 | 2002-04-02 | Birinder R. Boveja | External stimulator for adjunct (add-on) treatment for neurological, neuropsychiatric, and urological disorders |
| US6353762B1 (en) * | 1999-04-30 | 2002-03-05 | Medtronic, Inc. | Techniques for selective activation of neurons in the brain, spinal cord parenchyma or peripheral nerve |
| US7155278B2 (en) * | 2003-04-21 | 2006-12-26 | Medtronic, Inc. | Neurostimulation to treat effects of sleep apnea |
| US20100016929A1 (en) * | 2004-01-22 | 2010-01-21 | Arthur Prochazka | Method and system for controlled nerve ablation |
| US20080071321A1 (en) * | 2004-06-10 | 2008-03-20 | Ndi Medical, Inc. | Systems and methods of neuromodulation stimulation for the restoration of sexual function |
| CA2579569C (en) * | 2004-09-08 | 2016-07-05 | Spinal Modulation Inc. | Neurostimulation methods and systems |
| US9205261B2 (en) * | 2004-09-08 | 2015-12-08 | The Board Of Trustees Of The Leland Stanford Junior University | Neurostimulation methods and systems |
| WO2006135791A2 (en) | 2005-06-09 | 2006-12-21 | Medtronic, Inc. | Peripheral nerve field stimulation and spinal cord stimulation |
| JP5108787B2 (ja) * | 2006-01-23 | 2012-12-26 | リハブトロニクス インコーポレイテッド | 埋め込まれた受動導体を介して電流を体組織へルーティングする方法 |
| US8612019B2 (en) * | 2007-05-23 | 2013-12-17 | Boston Scientific Neuromodulation Corporation | Coupled monopolar and multipolar pulsing for conditioning and stimulation |
| US20090204173A1 (en) * | 2007-11-05 | 2009-08-13 | Zi-Ping Fang | Multi-Frequency Neural Treatments and Associated Systems and Methods |
| US8532779B2 (en) * | 2008-10-31 | 2013-09-10 | Medtronic, Inc. | Implantable medical device crosstalk evaluation and mitigation |
| US8996116B2 (en) * | 2009-10-30 | 2015-03-31 | Setpoint Medical Corporation | Modulation of the cholinergic anti-inflammatory pathway to treat pain or addiction |
| US20130053922A1 (en) * | 2009-10-22 | 2013-02-28 | Zaghloul Ahmed | Dipole electrical stimulation employing direct current for recovery from spinal cord injury |
| CA2829189A1 (en) * | 2010-03-22 | 2011-09-29 | Research Foundation Of The City University Of New York | Charge-enhanced neural electric stimulation system |
| US9724509B2 (en) * | 2010-06-07 | 2017-08-08 | Medtronic, Inc. | Selective termination of stimulation to deliver post-stimulation therapeutic effect |
| WO2012003451A2 (en) * | 2010-07-01 | 2012-01-05 | Stimdesigns Llc | Universal closed-loop electrical stimulation system |
| BR112013024491A2 (pt) * | 2011-03-24 | 2017-03-21 | California Inst Of Techn | neuroestimulador. |
| AU2012304370B2 (en) * | 2011-09-08 | 2016-01-28 | Nevro Corporation | Selective high frequency spinal cord modulation for inhibiting pain, including cephalic and/or total body pain with reduced side effects, and associated systems and methods |
| EP2785412B1 (en) * | 2011-11-29 | 2017-07-12 | Cardiac Pacemakers, Inc. | Autonomic modulation using peripheral nerve field stimulation |
| US8706240B2 (en) * | 2011-12-09 | 2014-04-22 | Boston Scientific Neuromodulation Corporation | Method for direct modulation of the spinothalamic tract |
| US9446239B2 (en) * | 2012-03-16 | 2016-09-20 | Boston Scientific Neuromodulation Corporation | Field augmented current steering using voltage sources |
| JP6212105B2 (ja) * | 2012-03-16 | 2017-10-11 | ボストン サイエンティフィック ニューロモデュレイション コーポレイション | 刺激デバイスと共に使用するための外部制御デバイス |
| EP2981330A4 (en) * | 2013-04-05 | 2017-01-04 | Waseem Ahmad | Devices and methods for airflow diagnosis and restoration |
| EP3082947B1 (en) * | 2013-12-22 | 2019-03-13 | Research Foundation Of The City University Of New York | Trans-spinal direct current modulation systems |
| US9707390B2 (en) * | 2013-12-22 | 2017-07-18 | The Research Foundation Of The City University Of New York | Apparatus for modulation of effector organs |
| US9707391B2 (en) * | 2013-12-22 | 2017-07-18 | The Research Foundation Of The City University Of New York | Method for modulation of effector organs |
-
2014
- 2014-12-22 EP EP14872635.9A patent/EP3082947B1/en active Active
- 2014-12-22 PT PT14872635T patent/PT3082947T/pt unknown
- 2014-12-22 SI SI201431236T patent/SI3082947T1/sl unknown
- 2014-12-22 DK DK14872635.9T patent/DK3082947T3/da active
- 2014-12-22 US US14/579,829 patent/US9283391B2/en active Active
- 2014-12-22 HU HUE14872635A patent/HUE045175T2/hu unknown
- 2014-12-22 ES ES14872635T patent/ES2732734T3/es active Active
- 2014-12-22 MX MX2016007586A patent/MX366919B/es active IP Right Grant
- 2014-12-22 ES ES19161879T patent/ES2889099T3/es active Active
- 2014-12-22 PL PL14872635T patent/PL3082947T3/pl unknown
- 2014-12-22 JP JP2016534630A patent/JP6518251B2/ja active Active
- 2014-12-22 KR KR1020167020164A patent/KR20160105822A/ko not_active Application Discontinuation
- 2014-12-22 KR KR1020197036685A patent/KR102431161B1/ko active IP Right Grant
- 2014-12-22 WO PCT/US2014/071959 patent/WO2015095880A2/en active Application Filing
- 2014-12-22 CN CN201811512717.9A patent/CN109432596B/zh active Active
- 2014-12-22 EP EP19161879.2A patent/EP3581239B1/en active Active
- 2014-12-22 LT LTEP14872635.9T patent/LT3082947T/lt unknown
- 2014-12-22 SG SG11201604288WA patent/SG11201604288WA/en unknown
- 2014-12-22 CA CA2932000A patent/CA2932000C/en active Active
- 2014-12-22 CN CN201480070353.7A patent/CN106029164B/zh active Active
- 2014-12-22 AU AU2014368874A patent/AU2014368874B2/en active Active
-
2016
- 2016-02-18 US US15/046,797 patent/US9844668B2/en active Active
- 2016-06-20 IL IL246430A patent/IL246430B/en active IP Right Grant
-
2017
- 2017-11-02 US US15/802,020 patent/US10493270B2/en active Active
-
2019
- 2019-06-07 HR HRP20191032TT patent/HRP20191032T1/hr unknown
- 2019-06-13 CY CY20191100617T patent/CY1122116T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HRP20191032T1 (hr) | Trans-spinalni modulacijski sustavi istosmjerne struje | |
| JP2017503537A5 (hr) | ||
| MX2021012225A (es) | Metodos y aparatos para el tratamiento estetico de estructuras biologicas mediante radiofrecuencia y energia magnetica. | |
| EP2959939A3 (en) | A hearing assistance device comprising an implantable part | |
| EP4257038A3 (en) | System for dynamically stimulating bone growth | |
| DK1843814T3 (da) | Anordning til transkutan stimulation af en nerve i det menneskelige legeme | |
| WO2017042539A3 (en) | Electrode apparatus | |
| WO2014153033A3 (en) | Systems and methods for treating human joints | |
| JP2015521521A5 (hr) | ||
| ATE520439T1 (de) | Hochspannungstolerante multiplexstimulationssysteme mit mehreren elektroden | |
| CO2019014876A2 (es) | Aparato y método para el control automatizado de la estimulación eléctrica del nervio transcutáneo basado en las condiciones climáticas actuales y previstas | |
| JP2016515026A5 (hr) | ||
| KR20160095579A (ko) | 남용으로 인한 부작용을 최소화하는 개인용 경두개직류자극장치 | |
| Souza et al. | Power amplifier circuits for functional electrical stimulation systems | |
| WO2016049047A3 (en) | Systems and methods for providing therapy using electrical stimulation to disrupt neuronal activity | |
| GB2502133A8 (en) | Treatment or therapeutic apparatus | |
| WO2016081468A3 (en) | Implantable electro-medical device programmable for improved operational life | |
| US8755904B2 (en) | Circuit arrangements for generating currents and the application thereof | |
| CN202191603U (zh) | 植入式双模刺激芯片及双模神经刺激系统 | |
| WO2018126779A1 (zh) | 无线可穿戴功能性电刺激系统辅助下的神经网络重建训练方法 | |
| JP2018518307A5 (hr) | ||
| ES2725914A1 (es) | Sistema de electro-estimulación de aplicación superficial sobre la piel | |
| US20210069495A1 (en) | Dynamic Current Steering | |
| TW202122128A (zh) | 輕型離子導入療法裝置 | |
| Lim et al. | A 16-channel neural stimulator with DAC sharing scheme for visual prostheses |