JP6517702B2 - 脱分化したリプログラミングされた細胞から導出された細胞組成物 - Google Patents

脱分化したリプログラミングされた細胞から導出された細胞組成物 Download PDF

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JP6517702B2
JP6517702B2 JP2015556262A JP2015556262A JP6517702B2 JP 6517702 B2 JP6517702 B2 JP 6517702B2 JP 2015556262 A JP2015556262 A JP 2015556262A JP 2015556262 A JP2015556262 A JP 2015556262A JP 6517702 B2 JP6517702 B2 JP 6517702B2
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cells
cell
endoderm
pluripotent
pdx1
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JP2016506736A5 (enExample
JP2016506736A (ja
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アラン ディー． アグルニック、
アラン ディー． アグルニック、
オリビア ケリー、
オリビア ケリー、
ユキ オオイ
ユキ オオイ
アラン ロビンス、
アラン ロビンス、
トーマス シュルツ、
トーマス シュルツ、
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ヴィアサイト インコーポレイテッド
ヴィアサイト インコーポレイテッド
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0012—Cell encapsulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
    • C—CHEMISTRY; METALLURGY
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C12N2501/72—Transferases [EC 2.]
    • C12N2501/727—Kinases (EC 2.7.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells

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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2015556262A 2013-02-06 2014-02-06 脱分化したリプログラミングされた細胞から導出された細胞組成物 Active JP6517702B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/761,078 2013-02-06
US13/761,078 US9109245B2 (en) 2009-04-22 2013-02-06 Cell compositions derived from dedifferentiated reprogrammed cells
PCT/US2014/015156 WO2014124172A1 (en) 2013-02-06 2014-02-06 Cell compositions derived from dedifferentiated reprogrammed cells

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JP2019078983A Division JP6721752B2 (ja) 2013-02-06 2019-04-18 脱分化したリプログラミングされた細胞から導出された細胞組成物

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JP2016506736A JP2016506736A (ja) 2016-03-07
JP2016506736A5 JP2016506736A5 (enExample) 2017-03-09
JP6517702B2 true JP6517702B2 (ja) 2019-05-22

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JP2015556262A Active JP6517702B2 (ja) 2013-02-06 2014-02-06 脱分化したリプログラミングされた細胞から導出された細胞組成物
JP2019078983A Active JP6721752B2 (ja) 2013-02-06 2019-04-18 脱分化したリプログラミングされた細胞から導出された細胞組成物
JP2020104982A Active JP7250731B2 (ja) 2013-02-06 2020-06-18 脱分化したリプログラミングされた細胞から導出された細胞組成物
JP2022172222A Active JP7550830B2 (ja) 2013-02-06 2022-10-27 脱分化したリプログラミングされた細胞から導出された細胞組成物
JP2024151116A Pending JP2025000625A (ja) 2013-02-06 2024-09-03 脱分化したリプログラミングされた細胞から導出された細胞組成物

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JP2019078983A Active JP6721752B2 (ja) 2013-02-06 2019-04-18 脱分化したリプログラミングされた細胞から導出された細胞組成物
JP2020104982A Active JP7250731B2 (ja) 2013-02-06 2020-06-18 脱分化したリプログラミングされた細胞から導出された細胞組成物
JP2022172222A Active JP7550830B2 (ja) 2013-02-06 2022-10-27 脱分化したリプログラミングされた細胞から導出された細胞組成物
JP2024151116A Pending JP2025000625A (ja) 2013-02-06 2024-09-03 脱分化したリプログラミングされた細胞から導出された細胞組成物

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EP (1) EP2954045A1 (enExample)
JP (5) JP6517702B2 (enExample)
AU (4) AU2014214879A1 (enExample)
CA (2) CA2898431C (enExample)
HK (1) HK1218139A1 (enExample)
IL (5) IL321825A (enExample)
RU (2) RU2675928C2 (enExample)
WO (1) WO2014124172A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9109245B2 (en) 2009-04-22 2015-08-18 Viacyte, Inc. Cell compositions derived from dedifferentiated reprogrammed cells
SG11201700874SA (en) 2014-08-04 2017-03-30 Takeda Pharmaceuticals Co Method for proliferation of pancreatic progenitor cells
MA45479A (fr) * 2016-04-14 2019-02-20 Janssen Biotech Inc Différenciation de cellules souches pluripotentes en cellules de l'endoderme de l'intestin moyen
EP3690022A1 (en) * 2016-05-18 2020-08-05 Keio University Cell culture medium for culturing organoid, culture method, and organoid
EP3587560A4 (en) 2017-01-27 2020-12-16 Kaneka Corporation Endodermal cell mass, and method for producing any one of three primary germ layer cell mass from pluripotent cells
NZ800904A (en) 2017-06-14 2025-08-29 Vertex Pharma Devices and methods for delivering therapeutics
EP3654996A4 (en) * 2017-07-21 2021-03-24 Semma Therapeutics, Inc. REAGGREGATION OF PANCREATIC BETA CELLS DERIVED FROM STEM CELLS
CN112912490B (zh) * 2018-08-03 2023-12-26 千纸鹤治疗公司 细胞制造方法
EP3854869A4 (en) * 2018-09-19 2022-09-07 Takeda Pharmaceutical Company Limited INSULIN-PRODUCING CELLS
EP3976236A1 (en) 2019-05-31 2022-04-06 W.L. Gore & Associates Inc. A biocompatible membrane composite
CA3257300A1 (en) 2019-05-31 2025-06-12 W. L. Gore & Associates, Inc. Cell encapsulation devices with controlled oxygen diffusion distances
EP3975926A1 (en) 2019-05-31 2022-04-06 W.L. Gore & Associates, Inc. A biocompatible membrane composite
CN114173837A (zh) 2019-05-31 2022-03-11 W.L.戈尔及同仁股份有限公司 生物相容性膜复合材料
IL300105A (en) 2020-07-31 2023-03-01 Vertex Pharma Pancreatic endocrine cell differentiation

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000059525A2 (en) * 1999-04-06 2000-10-12 Genentech, Inc. USE OF ErbB RECEPTOR LIGANDS IN TREATING DIABETES
US6759039B2 (en) * 2000-06-30 2004-07-06 Amcyte, Inc. Culturing pancreatic stem cells having a specified, intermediate stage of development
WO2002059278A2 (en) * 2001-01-24 2002-08-01 The Government Of The United States Of America, As Represented By The Secretary Of Department Of Health & Human Services Differentiation of stem cells to pancreatic endocrine cells
SG169324A1 (en) * 2005-10-14 2011-03-30 Univ Minnesota Differentiation of non-embryonic stem cells to cells having a pancreatic phenotype
WO2007143193A1 (en) * 2006-06-02 2007-12-13 University Of Georgia Research Foundation, Inc. Pancreatic and liver endoderm cells and tissue by differentiation of definitive endoderm cells obtained from human embryonic stems
JP2012508584A (ja) * 2008-11-14 2012-04-12 ヴィアサイト，インコーポレイテッド ヒト多能性幹細胞由来膵臓細胞のカプセル化
DK2421957T3 (da) * 2009-04-22 2021-01-25 Viacyte Inc Cellesammensætninger afledt af dedifferentierede omprogrammerede celler
US9109245B2 (en) * 2009-04-22 2015-08-18 Viacyte, Inc. Cell compositions derived from dedifferentiated reprogrammed cells
US8685726B2 (en) * 2009-04-27 2014-04-01 Viacyte, Inc. Small molecules supporting pluripotent cell growth and methods thereof

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RU2018144412A3 (enExample) 2020-02-14
IL239953A0 (en) 2015-08-31
AU2022200075C1 (en) 2023-07-06
EP2954045A1 (en) 2015-12-16
JP6721752B2 (ja) 2020-07-15
WO2014124172A1 (en) 2014-08-14
IL290717B1 (en) 2024-06-01
IL290717A (en) 2022-04-01
JP2025000625A (ja) 2025-01-07
IL311689B1 (en) 2025-08-01
CA2898431C (en) 2023-10-17
CA3212301A1 (en) 2014-08-14
RU2015131279A (ru) 2017-03-13
JP7550830B2 (ja) 2024-09-13
AU2019201314A1 (en) 2019-03-14
AU2019201314B2 (en) 2021-10-14
RU2754089C2 (ru) 2021-08-26
RU2675928C2 (ru) 2018-12-25
IL311689B2 (en) 2025-12-01
AU2023202507A1 (en) 2023-05-11
AU2014214879A1 (en) 2015-07-30
JP2016506736A (ja) 2016-03-07
JP7250731B2 (ja) 2023-04-03
RU2018144412A (ru) 2019-03-25
IL239953B (en) 2021-05-31
IL290717B2 (en) 2024-10-01
CA2898431A1 (en) 2014-08-14
IL283088B (en) 2022-04-01
IL311689A (en) 2024-05-01
AU2022200075A1 (en) 2022-02-03
JP2023017838A (ja) 2023-02-07
JP2019146578A (ja) 2019-09-05
IL321825A (en) 2025-08-01
JP2020178694A (ja) 2020-11-05
AU2023202507B2 (en) 2025-12-04
AU2022200075B2 (en) 2023-02-02
HK1218139A1 (zh) 2017-02-03
IL283088A (en) 2021-06-30

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