JP6465857B2 - 外科的に摘出された組織における癌細胞の生存能を維持するための方法および試薬 - Google Patents

外科的に摘出された組織における癌細胞の生存能を維持するための方法および試薬 Download PDF

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JP6465857B2
JP6465857B2 JP2016503010A JP2016503010A JP6465857B2 JP 6465857 B2 JP6465857 B2 JP 6465857B2 JP 2016503010 A JP2016503010 A JP 2016503010A JP 2016503010 A JP2016503010 A JP 2016503010A JP 6465857 B2 JP6465857 B2 JP 6465857B2
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reagent
cell
cosmotrope
buffer
cells
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ベイカー，トニー，ケイ
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トラッキー・アプライド・ゲノミクス，エルエルシー
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Physiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2016503010A 2013-03-15 2014-03-14 外科的に摘出された組織における癌細胞の生存能を維持するための方法および試薬 Active JP6465857B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361798627P 2013-03-15 2013-03-15
US61/798,627 2013-03-15
PCT/US2014/029198 WO2014144682A1 (en) 2013-03-15 2014-03-14 Methods and reagents for maintaining the viability of cancer cells in surgically removed tissue

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JP2016512693A JP2016512693A (ja) 2016-05-09
JP2016512693A5 JP2016512693A5 (https=) 2017-04-13
JP6465857B2 true JP6465857B2 (ja) 2019-02-06

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US (5) US9113623B2 (https=)
EP (2) EP2970878B1 (https=)
JP (1) JP6465857B2 (https=)
CN (2) CN112806352A (https=)
CA (1) CA2941929C (https=)
CY (1) CY1120801T1 (https=)
DK (1) DK2970878T3 (https=)
ES (1) ES2684582T3 (https=)
HR (1) HRP20181352T1 (https=)
HU (1) HUE039933T2 (https=)
LT (1) LT2970878T (https=)
PL (1) PL2970878T3 (https=)
PT (1) PT2970878T (https=)
RS (1) RS57900B1 (https=)
SI (1) SI2970878T1 (https=)
SM (1) SMT201800457T1 (https=)
WO (1) WO2014144682A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT2970878T (lt) 2013-03-15 2018-11-12 Truckee Applied Genomics, Llc Vėžio ląstelių chirurginiu būdu pašalintame audinyje gyvybingumo palaikymo būdai ir reagenatai
US10053676B2 (en) 2014-11-25 2018-08-21 Bio-Rad Laboratories, Inc. Arginine improves polymerase storage stability
CN107333750A (zh) * 2017-06-11 2017-11-10 成都吱吖科技有限公司 一种长时血液细胞稳定剂
WO2021055170A1 (en) * 2019-09-17 2021-03-25 Longhorn Vaccines And Diagnostics, Llc Multipurpose compositions for collecting and transporting biological material
WO2022010916A1 (en) * 2020-07-07 2022-01-13 Truckee Applied Genomics, Llc Cell preservation reagents and methods of use
CN117063915B (zh) * 2023-08-17 2026-02-24 镜像绮点(上海)细胞技术有限公司 原代肿瘤细胞冻存液

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5409826A (en) * 1993-06-08 1995-04-25 Coulter Corporation Preserved, non-infectious control cells prepared by the modulation or modification of normal cells
CA2250570A1 (en) * 1996-03-26 1997-10-02 Eli Lilly And Company Formulations of ob protein
US20010007673A1 (en) 1999-11-12 2001-07-12 Merrill Seymour Goldenberg Sustained-release delayed gels
US7569342B2 (en) 1997-12-10 2009-08-04 Sierra Molecular Corp. Removal of molecular assay interferences
US20080064108A1 (en) 1997-12-10 2008-03-13 Tony Baker Urine Preservation System
WO1999029904A2 (en) 1997-12-10 1999-06-17 Sierra Diagnostics, Inc. Methods and reagents for preservation of dna in bodily fluids
AU1848602A (en) * 2000-12-04 2002-06-18 Lymphotec Inc. Cell-preservation liquid and method of preserving cells by using the liquid
KR20020066778A (ko) 2001-02-13 2002-08-21 한국과학기술연구원 체내 난흡수 물질의 흡수촉진용 조성물과 제형 및 그의제조방법
WO2008111981A1 (en) 2007-03-14 2008-09-18 Sierra Molecular Corporation Compositions, systems, and methods for preservation of macromolecules
WO2004052184A2 (en) * 2002-12-12 2004-06-24 Oncotech, Inc. Genes related to sensitivity and resistance to chemotherapeutic drug treatment
US8793895B2 (en) * 2006-02-10 2014-08-05 Praxair Technology, Inc. Lyophilization system and method
US8652782B2 (en) * 2006-09-12 2014-02-18 Longhorn Vaccines & Diagnostics, Llc Compositions and methods for detecting, identifying and quantitating mycobacterial-specific nucleic acids
US8080645B2 (en) * 2007-10-01 2011-12-20 Longhorn Vaccines & Diagnostics Llc Biological specimen collection/transport compositions and methods
WO2008033936A2 (en) 2006-09-12 2008-03-20 Sierra Molecular Corporation Removal of molecular assay interferences for nucleic acids employing buffered solutions of chaotropes
WO2008052170A2 (en) 2006-10-27 2008-05-02 Sierra Molecular Corporation Penetratable septum cap
WO2008071384A1 (en) 2006-12-13 2008-06-19 Roche Diagnostics Gmbh Use of tde for the isolation of nucleic acids
KR20100015578A (ko) 2007-03-14 2010-02-12 시에라 몰레큘러 코포레이션 세포 및/또는 거대분자의 보존 및/또는 안정화를 위한 조성물, 시스템 및 방법
EP2217244A4 (en) * 2007-11-12 2011-08-31 Bipar Sciences Inc TREATMENT OF NUTRITIONAL CANCER AND EGG CANCER WITH A PARP INHIBITOR ALONE OR IN COMBINATION WITH ANTITUMOROUS MEDICINES
US20100003748A1 (en) 2008-07-03 2010-01-07 Tony Baker Compositions, systems, and methods for stabilization of a cell and/or macromolecule
WO2010028156A2 (en) 2008-09-04 2010-03-11 Board Of Regents, The University Of Texas System Dual modality detection of apoptosis
US9133343B2 (en) * 2009-11-30 2015-09-15 Enzo Biochem, Inc. Dyes and compositions, and processes for using same in analysis of protein aggregation and other applications
CN102318597B (zh) * 2011-08-19 2013-04-03 张雪云 一种液基细胞保存液组合物及其制备方法
LT2970878T (lt) 2013-03-15 2018-11-12 Truckee Applied Genomics, Llc Vėžio ląstelių chirurginiu būdu pašalintame audinyje gyvybingumo palaikymo būdai ir reagenatai

Also Published As

Publication number Publication date
US20140272921A1 (en) 2014-09-18
PL2970878T3 (pl) 2019-01-31
CY1120801T1 (el) 2019-12-11
US9949474B2 (en) 2018-04-24
RS57900B1 (sr) 2019-01-31
WO2014144682A8 (en) 2015-08-13
PT2970878T (pt) 2018-10-09
SMT201800457T1 (it) 2018-11-09
HUE039933T2 (hu) 2019-02-28
EP2970878A4 (en) 2016-08-03
US20160235055A1 (en) 2016-08-18
CN105121629A (zh) 2015-12-02
HK1220481A1 (en) 2017-05-05
US20150327539A1 (en) 2015-11-19
CA2941929A1 (en) 2014-09-18
US9113623B2 (en) 2015-08-25
CN105121629B (zh) 2020-12-18
EP3581643A1 (en) 2019-12-18
US9565852B2 (en) 2017-02-14
US10772318B2 (en) 2020-09-15
EP2970878A1 (en) 2016-01-20
US20170215410A1 (en) 2017-08-03
JP2016512693A (ja) 2016-05-09
WO2014144682A1 (en) 2014-09-18
CA2941929C (en) 2021-02-23
ES2684582T3 (es) 2018-10-03
SI2970878T1 (sl) 2019-02-28
HRP20181352T1 (hr) 2018-12-14
LT2970878T (lt) 2018-11-12
US20150230454A1 (en) 2015-08-20
EP2970878B1 (en) 2018-05-23
WO2014144682A4 (en) 2014-12-24
CN112806352A (zh) 2021-05-18
DK2970878T3 (en) 2018-09-03
US9445586B2 (en) 2016-09-20

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