JP6430546B2 - 満腹応答を誘導するためのペットフード組成物 - Google Patents
満腹応答を誘導するためのペットフード組成物 Download PDFInfo
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/111—Aromatic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/40—Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/105—Aliphatic or alicyclic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/142—Amino acids; Derivatives thereof
- A23K20/147—Polymeric derivatives, e.g. peptides or proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/158—Fatty acids; Fats; Products containing oils or fats
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/174—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/40—Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
- A23K50/48—Moist feed
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Animal Husbandry (AREA)
- Food Science & Technology (AREA)
- Birds (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
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Description
好ましい実施形態の以下の説明は、事実上は単なる例示であり、本発明、その応用または用途を限定することを意図するものではない。
例えば、該満腹誘導剤がレプチンおよび/またはその受容体の発現を増大し、かつ/または、該満腹誘導剤がレプチンおよびその受容体の発現を減少させるものである;
例えば、調節される遺伝子がNPY、ペプチドYY Y2受容体およびNPY1Rから選択されるものである;
例えば、満腹誘導剤がベータ−カロテン、トマトパウダーおよびレスベラトロール(resveratrol)から選択されるものである;
あるいは、該満腹誘導剤がベータ−カロテン、トマトパウダーおよびレスベラトロールから選択され、かつ、該動物がネコである、ペットフード組成物(組成物1)を提供する。
Affymetrix Genechip発現解析
Affymetrix, Inc.(95051カリフォルニア州サンタクララ)により調製される、注文生産商品のfeline GeneChip登録商標アレイを用いて、遺伝子発現を解析した。全RNAをcDNAに逆転写する。このcDNAを用いてcRNAを生成させ、断片化し、GeneChipハイブリダイゼーションのためのプローブとして用いる。ジーンチップを洗浄し、ハイブリダイゼーションシグナルをAffymetrixレーザースキャナで測定する。次いで、このハイブリダイゼーションデータをさらなる解析のために確認および標準化する。
Claims (17)
- 満腹応答を誘導するのに有効な量で満腹誘導剤を含むペットフード組成物であって、ここに、該満腹誘導剤は、NPY受容体およびペプチドYY受容体から選択される一以上の遺伝子の発現を調節するのに有効であり、かつ、該満腹誘導剤は、トマトパウダーを含む、ペットフード組成物。
- トマトパウダーが30mgから4500mgの量である、請求項1に記載のペットフード組成物。
- 動物がネコである、請求項1または2に記載のペットフード組成物。
- 0−90重量%の炭水化物;
5−70重量%のタンパク質;
2−50重量%の脂肪;
0.1−20重量%の全食物繊維;および
0−15重量%のビタミンおよびミネラル
をさらに含む、請求項1〜3のいずれかに記載のペットフード組成物。 - 前記満腹誘導剤が、レスベラトロールまたはベータ−カロテンをさらに含む、請求項1〜4のいずれかに記載のペットフード組成物。
- レスベラトロールが3mgから450mgの量である、請求項5に記載のペットフード組成物。
- ベータ−カロテンが1.8mgから270mgの量である、請求項5または請求項6に記載のペットフード組成物。
- 有効量の請求項1−7のいずれか一項に記載のペットフード組成物を動物に与えることを含む、満腹応答を誘導する方法。
- ペットフード組成物が、該動物に適した大きさおよび年齢階級における動物の栄養所要量を供給するために調製される、請求項8に記載の方法。
- 請求項1−7のいずれか一項に記載のペットフード組成物を動物に与えることを含む、動物の食物摂取の量を制御する方法であって、該満腹誘導剤は、適した栄養素含有量が消費される際に該動物が摂食を停止するようにする量で存在するものである、方法。
- ペットフード組成物が、該動物に適した大きさおよび年齢階級における動物の栄養所要量を供給するために調製される、請求項10に記載の方法。
- 満腹応答を誘導するのに有効な量で満腹誘導剤を含むペットフード組成物の使用であって、ここに、該満腹誘導剤は、NPY受容体およびペプチドYY受容体から選択される一以上の遺伝子の発現を調節するのに有効であり、かつ、該満腹誘導剤は、トマトパウダーを含む、使用。
- トマトパウダーが30mgから4500mgの量である、請求項12に記載の使用。
- ペットフード組成物が、
0−90重量%の炭水化物;
5−70重量%のタンパク質;
2−50重量%の脂肪;
0.1−20重量%の全食物繊維;および
0−15重量%のビタミンおよびミネラル
をさらに含む、請求項12または請求項13に記載の使用。 - 前記満腹誘導剤が、レスベラトロールまたはベータ−カロテンをさらに含む、請求項12〜14のいずれかに記載の使用。
- レスベラトロールが3mgから450mgの量である、請求項15に記載の使用。
- ベータ−カロテンが1.8mgから270mgの量である、請求項15または請求項16に記載の使用。
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