JP6426001B2 - 神経膠腫を治療するための組成物および方法 - Google Patents
神経膠腫を治療するための組成物および方法 Download PDFInfo
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
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| US201161561080P | 2011-11-17 | 2011-11-17 | |
| US61/561,080 | 2011-11-17 | ||
| US201261583745P | 2012-01-06 | 2012-01-06 | |
| US61/583,745 | 2012-01-06 | ||
| PCT/IB2012/056533 WO2013072901A2 (en) | 2011-11-17 | 2012-11-18 | Compositions and methods for treating glioma |
Publications (3)
| Publication Number | Publication Date |
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| JP2014533681A JP2014533681A (ja) | 2014-12-15 |
| JP2014533681A5 JP2014533681A5 (https=) | 2016-01-14 |
| JP6426001B2 true JP6426001B2 (ja) | 2018-11-21 |
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| JP (1) | JP6426001B2 (https=) |
| KR (1) | KR20140103122A (https=) |
| CA (1) | CA2856329A1 (https=) |
| IL (1) | IL232648B (https=) |
| WO (1) | WO2013072901A2 (https=) |
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| GB201220573D0 (en) | 2012-11-15 | 2013-01-02 | Univ Central Lancashire | Methods of diagnosing proliferative disorders |
| DE102014207498A1 (de) * | 2014-04-17 | 2015-10-22 | Universitätsklinikum Hamburg-Eppendorf | Viraler Vektor für den zielgerichteten Gentransfer in Gehirn und Rückenmark |
| CA2962757C (en) * | 2014-09-26 | 2022-03-22 | National University Of Singapore | Methods and compositions for modulating th-gm cell function |
| US11078264B2 (en) * | 2018-10-17 | 2021-08-03 | University Of Connecticut | Inhibiting granulocyte macrophage-colony stimulating factor (GM-CSF) prevents preterm birth |
| US12582695B2 (en) * | 2018-11-28 | 2026-03-24 | Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polska Akademia Nauk | Compositions and methods for treating glioma |
| CN112007142B (zh) * | 2019-05-31 | 2025-04-22 | 生物蚕茧研究所股份有限公司 | 向抗炎m2表型小胶质细胞的极性转化促进剂 |
| PL441229A1 (pl) * | 2022-05-19 | 2023-11-20 | Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polska Akademia Nauk | Zaprojektowane, syntetyczne peptydy, zawierające je kompozycje i sposoby ich zastosowania w leczeniu glejaków złośliwych |
| KR102899196B1 (ko) * | 2023-01-20 | 2025-12-12 | (주) 넥셀 | 치주염 및 임플란트 주변염 예방 또는 치료용 재조합 단백질 및 이를 포함하는 치주염 및 임플란트 주변염 예방 또는 치료용 조성물 |
| CN116650650A (zh) * | 2023-06-12 | 2023-08-29 | 郑州大学 | 一种抑制食管鳞癌中肿瘤相关巨噬细胞浸润的方法 |
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| US6410516B1 (en) | 1986-01-09 | 2002-06-25 | President & Fellows Of Harvard College | Nuclear factors associated with transcriptional regulation |
| EP0482086A1 (en) * | 1989-07-14 | 1992-04-29 | Schering Corporation | Antagonists of gm-csf derived from the carboxyl terminus |
| EP0486572B1 (en) * | 1989-08-11 | 1998-01-07 | Amrad Corporation Limited | Improvements in granulocyte-macrophage colony-stimulating factor receptor and derivatives thereof |
| AUPN780096A0 (en) * | 1996-01-30 | 1996-02-22 | Medvet Science Pty. Ltd. | Cytokine antagonists and agonists |
| US5837231A (en) * | 1996-06-27 | 1998-11-17 | Regents Of The University Of Minnesota | GM-CSF administration for the treatment and prevention of recurrence of brain tumors |
| US6372720B1 (en) | 1998-02-05 | 2002-04-16 | Kenneth J. Longmuir | Liposome fusion and delivery vehicle |
| AU756916B2 (en) | 1998-11-12 | 2003-01-23 | Jcr Pharmaceuticals Co., Ltd. | Modulation of cell proliferative disorders by cyclic RGD |
| US6551990B2 (en) * | 1998-12-07 | 2003-04-22 | University Of Washington | Methods of inhibiting ectopic calcification |
| AU2592600A (en) | 1998-12-23 | 2000-07-31 | G.D. Searle & Co. | Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia |
| US6521593B1 (en) | 1999-02-01 | 2003-02-18 | Childrens Hospital Los Angeles | Methods for inhibiting brain tumor growth |
| ATE507295T1 (de) * | 2000-03-30 | 2011-05-15 | Dendreon Corp | Zusammensetzungen und verfahren für eine auf dendritischen zellen basierende immuntherapie |
| US7767802B2 (en) | 2001-01-09 | 2010-08-03 | Alnylam Pharmaceuticals, Inc. | Compositions and methods for inhibiting expression of anti-apoptotic genes |
| US7611711B2 (en) * | 2001-01-17 | 2009-11-03 | Vegenics Limited | VEGFR-3 inhibitor materials and methods |
| AU2002323151A1 (en) | 2001-08-13 | 2003-03-03 | University Of Pittsburgh | Application of lipid vehicles and use for drug delivery |
| AU2003276828A1 (en) * | 2002-05-10 | 2004-03-11 | Children's Medical Center Corporation | Minicell display and products therefrom |
| DE602006017806D1 (de) * | 2005-02-18 | 2010-12-09 | Proximagen Ltd | Behandlung von neurodegeneration |
| EP2385061A3 (en) * | 2005-05-10 | 2012-02-22 | Neoloch Aps | Neuritogenic peptides |
| CA2663749A1 (en) * | 2005-09-21 | 2007-03-29 | Dask Technologies, Llc | Methods and compositions for organ and tissue functionality |
| BRPI0706540A2 (pt) | 2006-01-18 | 2011-03-29 | Merck Patent Gmbh | terapia especìfica usando ligantes de integrina para tratar cáncer |
| MX2008012291A (es) * | 2006-03-27 | 2009-01-12 | Medimmune Ltd | Miembro que enlaza al receptor gm-csf. |
| DK2121586T3 (en) | 2007-03-09 | 2017-06-19 | Pathologica Llc | MGBG FOR THE REGULATION OF OSTEOPONTIN AND THE TREATMENT OF MULTIPLE SCLEROSIS |
| DK2201138T3 (en) | 2007-10-16 | 2015-05-18 | Ventana Med Syst Inc | GRADING, STAGE DETERMINATION AND FORECAST OF CANCER USING osteopontin-C |
| KR20200075044A (ko) * | 2008-01-22 | 2020-06-25 | 아라임 파마슈티칼즈, 인크. | 조직 손상 관련 질환 및 장애를 예방 및 치료하기 위한 조직 보호 펩티드 및 펩티드 유사체 |
| KR20110086757A (ko) | 2008-11-20 | 2011-07-29 | 메르크 파텐트 게엠베하 | 암을 치료하기 위해 인테그린 리간드를 사용하는 신규한 치료요법 및 약제 |
| CN102448497A (zh) | 2009-05-25 | 2012-05-09 | 默克专利有限公司 | 在癌症治疗中的西仑吉肽的持续给药 |
| BR112012027745A2 (pt) * | 2010-04-27 | 2017-01-10 | Univ Johns Hopkins | método e composição imunogênica para tratamento de neoplásia |
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| US9453050B2 (en) | 2016-09-27 |
| US20140256628A1 (en) | 2014-09-11 |
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| IL232648A0 (en) | 2014-06-30 |
| CA2856329A1 (en) | 2013-05-23 |
| KR20140103122A (ko) | 2014-08-25 |
| EP2780363B1 (en) | 2019-07-03 |
| US20170035851A1 (en) | 2017-02-09 |
| WO2013072901A2 (en) | 2013-05-23 |
| JP2014533681A (ja) | 2014-12-15 |
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