JP6426001B2 - 神経膠腫を治療するための組成物および方法 - Google Patents
神経膠腫を治療するための組成物および方法 Download PDFInfo
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- A61K38/19—Cytokines; Lymphokines; Interferons
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
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- Chemical & Material Sciences (AREA)
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- Medicinal Chemistry (AREA)
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| US201261583745P | 2012-01-06 | 2012-01-06 | |
| US61/583,745 | 2012-01-06 | ||
| PCT/IB2012/056533 WO2013072901A2 (en) | 2011-11-17 | 2012-11-18 | Compositions and methods for treating glioma |
Publications (3)
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| JP2014533681A JP2014533681A (ja) | 2014-12-15 |
| JP2014533681A5 JP2014533681A5 (https=) | 2016-01-14 |
| JP6426001B2 true JP6426001B2 (ja) | 2018-11-21 |
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| CA (1) | CA2856329A1 (https=) |
| IL (1) | IL232648B (https=) |
| WO (1) | WO2013072901A2 (https=) |
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| GB201220573D0 (en) | 2012-11-15 | 2013-01-02 | Univ Central Lancashire | Methods of diagnosing proliferative disorders |
| DE102014207498A1 (de) * | 2014-04-17 | 2015-10-22 | Universitätsklinikum Hamburg-Eppendorf | Viraler Vektor für den zielgerichteten Gentransfer in Gehirn und Rückenmark |
| SG11201702475VA (en) * | 2014-09-26 | 2017-04-27 | Univ Singapore | Methods and compositions for modulating th-gm cell function |
| US11078264B2 (en) | 2018-10-17 | 2021-08-03 | University Of Connecticut | Inhibiting granulocyte macrophage-colony stimulating factor (GM-CSF) prevents preterm birth |
| WO2020110117A1 (en) * | 2018-11-28 | 2020-06-04 | Glia Sp. Z O.O. | Compositions and methods for treating glioma |
| CN112007142B (zh) * | 2019-05-31 | 2025-04-22 | 生物蚕茧研究所股份有限公司 | 向抗炎m2表型小胶质细胞的极性转化促进剂 |
| PL441229A1 (pl) * | 2022-05-19 | 2023-11-20 | Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polska Akademia Nauk | Zaprojektowane, syntetyczne peptydy, zawierające je kompozycje i sposoby ich zastosowania w leczeniu glejaków złośliwych |
| KR102899196B1 (ko) * | 2023-01-20 | 2025-12-12 | (주) 넥셀 | 치주염 및 임플란트 주변염 예방 또는 치료용 재조합 단백질 및 이를 포함하는 치주염 및 임플란트 주변염 예방 또는 치료용 조성물 |
| CN116650650A (zh) * | 2023-06-12 | 2023-08-29 | 郑州大学 | 一种抑制食管鳞癌中肿瘤相关巨噬细胞浸润的方法 |
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| WO1991002063A1 (en) * | 1989-08-11 | 1991-02-21 | Amrad Corporation Limited | Improvements in granulocyte-macrophage colony-stimulating factor receptor and derivatives thereof |
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| US5837231A (en) * | 1996-06-27 | 1998-11-17 | Regents Of The University Of Minnesota | GM-CSF administration for the treatment and prevention of recurrence of brain tumors |
| US6372720B1 (en) | 1998-02-05 | 2002-04-16 | Kenneth J. Longmuir | Liposome fusion and delivery vehicle |
| CA2288680A1 (en) | 1998-11-12 | 2000-05-12 | Jcr Pharmaceuticals Co., Ltd. | Modulation of cell proliferative disorders by cyclic rgd |
| US6551990B2 (en) * | 1998-12-07 | 2003-04-22 | University Of Washington | Methods of inhibiting ectopic calcification |
| BR9916536A (pt) | 1998-12-23 | 2002-01-02 | Searle & Co | Método para o tratamento ou prevenção de um distúrbio de neoplasia em um mamìfero em necessidade deste tratamento ou prevenção, e, combinação |
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| WO2001074855A2 (en) * | 2000-03-30 | 2001-10-11 | Dendreon Corporation | Compositions and methods for dendritic cell-based immunotherapy |
| US7767802B2 (en) | 2001-01-09 | 2010-08-03 | Alnylam Pharmaceuticals, Inc. | Compositions and methods for inhibiting expression of anti-apoptotic genes |
| US7611711B2 (en) * | 2001-01-17 | 2009-11-03 | Vegenics Limited | VEGFR-3 inhibitor materials and methods |
| US7063860B2 (en) | 2001-08-13 | 2006-06-20 | University Of Pittsburgh | Application of lipid vehicles and use for drug delivery |
| WO2004018498A2 (en) * | 2002-05-10 | 2004-03-04 | Children's Medical Center Corporation | Minicell display and products therefrom |
| WO2006087579A1 (en) * | 2005-02-18 | 2006-08-24 | Proximagen Ltd. | Treatment for neurodegeneration |
| EP2377884A1 (en) * | 2005-05-10 | 2011-10-19 | Neoloch Aps | Neuritogenic peptides |
| WO2007035843A2 (en) * | 2005-09-21 | 2007-03-29 | Dask Technologies, Llc | Methods and compositions for organ and tissue functionality |
| AU2007207465B2 (en) | 2006-01-18 | 2012-12-06 | Merck Patent Gmbh | Specific therapy using integrin ligands for treating cancer |
| PL1999152T3 (pl) * | 2006-03-27 | 2013-05-31 | Medimmune Ltd | Element wiążący receptor GM-CSF |
| DK2121586T3 (en) | 2007-03-09 | 2017-06-19 | Pathologica Llc | MGBG FOR THE REGULATION OF OSTEOPONTIN AND THE TREATMENT OF MULTIPLE SCLEROSIS |
| ES2538362T3 (es) | 2007-10-16 | 2015-06-19 | Ventana Medical Systems, Inc. | Clasificación, estadificación y pronóstico del cáncer mediante el uso de osteopontina-C |
| WO2009094172A2 (en) * | 2008-01-22 | 2009-07-30 | Araim Pharmaceuticals, Inc. | Tissue protective peptides and peptide analogs for preventing and treating diseases and disorders associated with tissue damage |
| CN102223915A (zh) | 2008-11-20 | 2011-10-19 | 默克专利有限公司 | 应用整联蛋白配体治疗癌症的新疗法和药物 |
| NZ597339A (en) | 2009-05-25 | 2013-10-25 | Merck Patent Gmbh | Continuous administration of cilengitide in cancer treatments |
| BR112012027745A2 (pt) * | 2010-04-27 | 2017-01-10 | Univ Johns Hopkins | método e composição imunogênica para tratamento de neoplásia |
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| CA2856329A1 (en) | 2013-05-23 |
| EP2780363A2 (en) | 2014-09-24 |
| KR20140103122A (ko) | 2014-08-25 |
| US20140256628A1 (en) | 2014-09-11 |
| US20170035851A1 (en) | 2017-02-09 |
| EP2780363B1 (en) | 2019-07-03 |
| JP2014533681A (ja) | 2014-12-15 |
| IL232648B (en) | 2021-12-01 |
| WO2013072901A2 (en) | 2013-05-23 |
| WO2013072901A3 (en) | 2013-07-25 |
| US9453050B2 (en) | 2016-09-27 |
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