JP6421123B2 - 出生前診断のための頚管粘液における胎性栄養膜細胞の同定および分析 - Google Patents

出生前診断のための頚管粘液における胎性栄養膜細胞の同定および分析 Download PDF

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JP6421123B2
JP6421123B2 JP2015538043A JP2015538043A JP6421123B2 JP 6421123 B2 JP6421123 B2 JP 6421123B2 JP 2015538043 A JP2015538043 A JP 2015538043A JP 2015538043 A JP2015538043 A JP 2015538043A JP 6421123 B2 JP6421123 B2 JP 6421123B2
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fetal
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trophoblast
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ディー． ランドール アルマント、
ディー． ランドール アルマント、
マイケル ピー． ダイアモンド、
マイケル ピー． ダイアモンド、
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ウェイン ステイト ユニヴァーシティ
ウェイン ステイト ユニヴァーシティ
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    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
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    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0605—Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
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    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G01N2333/70539—MHC-molecules, e.g. HLA-molecules
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/36—Gynecology or obstetrics
    • G01N2800/368—Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour

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  • Urology & Nephrology (AREA)
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  • Tropical Medicine & Parasitology (AREA)
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  • Food Science & Technology (AREA)
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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
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JP2015538043A 2012-10-19 2013-10-18 出生前診断のための頚管粘液における胎性栄養膜細胞の同定および分析 Active JP6421123B2 (ja)

Applications Claiming Priority (3)

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US201261715854P 2012-10-19 2012-10-19
US61/715,854 2012-10-19
PCT/US2013/065570 WO2014062995A1 (en) 2012-10-19 2013-10-18 Identification and analysis of fetal trophoblast cells in cervical mucus for prenatal diagnosis

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JP2015533504A JP2015533504A (ja) 2015-11-26
JP6421123B2 true JP6421123B2 (ja) 2018-11-07

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US (1) US10344315B2 (https=)
EP (1) EP2909315B1 (https=)
JP (1) JP6421123B2 (https=)
AU (1) AU2013331171B2 (https=)
CA (1) CA2888746C (https=)
DK (1) DK2909315T3 (https=)
ES (1) ES2729182T3 (https=)
IN (1) IN2015DN03186A (https=)
TR (1) TR201908019T4 (https=)
WO (1) WO2014062995A1 (https=)

Families Citing this family (12)

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Publication number Priority date Publication date Assignee Title
CA2888746C (en) 2012-10-19 2022-07-26 Wayne State University Identification and analysis of fetal trophoblast cells in cervical mucus for prenatal diagnosis
WO2016057993A1 (en) 2014-10-10 2016-04-14 Wayne State University Methods and compositions relating to assays of fetal extravillous trophoblast cells
US10808239B2 (en) 2016-04-06 2020-10-20 Wayne State University Isolation and analysis of fetal DNA from extravillous trophoblast cells retrieved from the endocervical canal
WO2017180909A1 (en) 2016-04-13 2017-10-19 Nextgen Jane, Inc. Sample collection and preservation devices, systems and methods
WO2019021065A2 (en) * 2017-02-13 2019-01-31 Trophodiagnostics, Llc NEW SYSTEM AND METHOD FOR COLLECTING, ENRICHING AND ISOLATING TROPHOBLASTIC CELLS FROM A ENDOCERVICAL CHANNEL
US11230729B2 (en) 2018-04-20 2022-01-25 Inanna Diagnostics, Inc Methods and devices for obtaining cellular and DNA material from human female reproductive system
TWI668423B (zh) * 2018-10-02 2019-08-11 吳宏偉 細胞分選方法及系統
CN111122857A (zh) * 2018-10-31 2020-05-08 苏州浚惠生物科技有限公司 胎儿滋养层细胞的标志物、鉴定方法、检测试剂盒和应用
CN111304153A (zh) * 2019-12-17 2020-06-19 广东凯普生物科技股份有限公司 一种分离滋养层细胞的方法
JP7824649B2 (ja) * 2020-02-21 2026-03-05 国立大学法人東海国立大学機構 胎児発育不全に対する定量的評価指標
CN112980779B (zh) * 2021-05-20 2021-08-24 广州凯普医药科技有限公司 一种从孕妇宫颈脱落细胞中分离胎盘滋养层细胞的方法
AU2023406050A1 (en) * 2022-11-29 2025-06-12 Akna Health Inc. Identification of cervical biomarkers

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US5629147A (en) 1992-07-17 1997-05-13 Aprogenex, Inc. Enriching and identifying fetal cells in maternal blood for in situ hybridization
DE69223617T2 (de) 1992-09-18 1998-04-09 Amersham Int Plc Verfahren zum Auffangen von Zellkernen und dafür verwendete Vorrichtung
BR9907852A (pt) * 1998-02-12 2000-10-24 Immunivest Corp Processos para detectar e enumerar células raras e cancerosas em uma população celular mista, para diagnosticar câncer de estágio precoce em um paciente de teste, para determinar a probabilidade de recorrência de câncer em um paciente humano anteriormente tratado de câncer, para distinguir um carcinoma confinado ao órgão de um carcinoma com propriedades metastáticas, para acompanhar a situação de remissão em um paciente humano com câncer que passa pelo tratamento de terapia contra o câncer e para aumentar quantidades de células epiteliais circulantes em uma amostra de sangue, partìcula magnética revestida, composição, conjuntos de teste para avaliar uma amostra de paciente quanto a presença de células raras circulantes, quanto a presença de células de tumor circulantes, quanto a presença de células de câncer de mama circulantes, quanto a presença de células de câncer de próstata circulantes, quanto a presença de células de câncer de cólon circulantes, quanto a presença de células de câncer de bexiga circulantes e para monitorar um paciente quanto a recorrência de câncer, e, fração de sangue periférico enriquecido quanto a células neoplásticas circulantes
AUPR749901A0 (en) * 2001-09-06 2001-09-27 Monash University Method of identifying chromosomal abnormalities and prenatal diagnosis
US20040197832A1 (en) * 2003-04-03 2004-10-07 Mor Research Applications Ltd. Non-invasive prenatal genetic diagnosis using transcervical cells
US20050181429A1 (en) 2003-04-03 2005-08-18 Monaliza Medical Ltd. Non-invasive prenatal genetic diagnosis using transcervical cells
JP2008514900A (ja) 2004-07-30 2008-05-08 アデザ・バイオメデイカル・コーポレイシヨン 疾病および他の状態のマーカーとしての癌胎児性フィブロネクチンならびに癌胎児性フィブロネクチンの検出のための方法
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Publication number Publication date
TR201908019T4 (tr) 2019-06-21
DK2909315T3 (da) 2019-06-03
EP2909315B1 (en) 2019-05-01
ES2729182T3 (es) 2019-10-30
HK1214294A1 (en) 2016-07-22
US10344315B2 (en) 2019-07-09
CA2888746C (en) 2022-07-26
EP2909315A4 (en) 2016-04-20
IN2015DN03186A (https=) 2015-10-02
US20150267240A1 (en) 2015-09-24
WO2014062995A1 (en) 2014-04-24
AU2013331171A1 (en) 2015-05-28
JP2015533504A (ja) 2015-11-26
AU2013331171B2 (en) 2019-05-30
EP2909315A1 (en) 2015-08-26
CA2888746A1 (en) 2014-04-24

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