DK2909315T3 - Identifikation og analyse af føtale trofoblastceller i cervixslim til prænatal diagnose - Google Patents

Identifikation og analyse af føtale trofoblastceller i cervixslim til prænatal diagnose Download PDF

Info

Publication number
DK2909315T3
DK2909315T3 DK13847056.2T DK13847056T DK2909315T3 DK 2909315 T3 DK2909315 T3 DK 2909315T3 DK 13847056 T DK13847056 T DK 13847056T DK 2909315 T3 DK2909315 T3 DK 2909315T3
Authority
DK
Denmark
Prior art keywords
prinatic
trophy
cervix
slim
diagnosis
Prior art date
Application number
DK13847056.2T
Other languages
English (en)
Inventor
Michael P Diamond
D Randall Armant
Original Assignee
Univ Wayne State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Wayne State filed Critical Univ Wayne State
Application granted granted Critical
Publication of DK2909315T3 publication Critical patent/DK2909315T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/24Methods of sampling, or inoculating or spreading a sample; Methods of physically isolating an intact microorganisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0603Embryonic cells ; Embryoid bodies
    • C12N5/0605Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2503/00Use of cells in diagnostics
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G01N2333/70539MHC-molecules, e.g. HLA-molecules
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/36Gynecology or obstetrics
    • G01N2800/368Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Pregnancy & Childbirth (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK13847056.2T 2012-10-19 2013-10-18 Identifikation og analyse af føtale trofoblastceller i cervixslim til prænatal diagnose DK2909315T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261715854P 2012-10-19 2012-10-19
PCT/US2013/065570 WO2014062995A1 (en) 2012-10-19 2013-10-18 Identification and analysis of fetal trophoblast cells in cervical mucus for prenatal diagnosis

Publications (1)

Publication Number Publication Date
DK2909315T3 true DK2909315T3 (da) 2019-06-03

Family

ID=50488767

Family Applications (1)

Application Number Title Priority Date Filing Date
DK13847056.2T DK2909315T3 (da) 2012-10-19 2013-10-18 Identifikation og analyse af føtale trofoblastceller i cervixslim til prænatal diagnose

Country Status (11)

Country Link
US (1) US10344315B2 (da)
EP (1) EP2909315B1 (da)
JP (1) JP6421123B2 (da)
AU (1) AU2013331171B2 (da)
CA (1) CA2888746C (da)
DK (1) DK2909315T3 (da)
ES (1) ES2729182T3 (da)
HK (1) HK1214294A1 (da)
IN (1) IN2015DN03186A (da)
TR (1) TR201908019T4 (da)
WO (1) WO2014062995A1 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2909315B1 (en) 2012-10-19 2019-05-01 Wayne State University Identification and analysis of fetal trophoblast cells in cervical mucus for prenatal diagnosis
EP3204536B1 (en) * 2014-10-10 2020-02-12 Wayne State University Methods relating to assays of fetal extravillous trophoblast cells
JP7026098B2 (ja) * 2016-04-06 2022-02-25 ウェイン ステート ユニバーシティ 子宮頸管より採取された絨毛外栄養膜細胞からの胎児dnaの単離と分析
WO2017180909A1 (en) 2016-04-13 2017-10-19 Nextgen Jane, Inc. Sample collection and preservation devices, systems and methods
WO2019021065A2 (en) * 2017-02-13 2019-01-31 Trophodiagnostics, Llc NEW SYSTEM AND METHOD FOR COLLECTING, ENRICHING AND ISOLATING TROPHOBLASTIC CELLS FROM A ENDOCERVICAL CHANNEL
US11230729B2 (en) 2018-04-20 2022-01-25 Inanna Diagnostics, Inc Methods and devices for obtaining cellular and DNA material from human female reproductive system
TWI668423B (zh) * 2018-10-02 2019-08-11 吳宏偉 細胞分選方法及系統
CN111122857A (zh) * 2018-10-31 2020-05-08 苏州浚惠生物科技有限公司 胎儿滋养层细胞的标志物、鉴定方法、检测试剂盒和应用
CN111304153A (zh) * 2019-12-17 2020-06-19 广东凯普生物科技股份有限公司 一种分离滋养层细胞的方法
JPWO2021167098A1 (da) * 2020-02-21 2021-08-26
CN112980779B (zh) * 2021-05-20 2021-08-24 广州凯普医药科技有限公司 一种从孕妇宫颈脱落细胞中分离胎盘滋养层细胞的方法
WO2024118661A2 (en) * 2022-11-29 2024-06-06 Akna Health Inc. Identification of cervical biomarkers

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5629147A (en) 1992-07-17 1997-05-13 Aprogenex, Inc. Enriching and identifying fetal cells in maternal blood for in situ hybridization
EP0587951B1 (en) 1992-09-18 1997-12-17 AMERSHAM INTERNATIONAL plc Cell nuclei capture method and device used therefor
WO1999041613A1 (en) * 1998-02-12 1999-08-19 Immunivest Methods and reagents for the rapid and efficient isolation of circulating cancer cells
AUPR749901A0 (en) 2001-09-06 2001-09-27 Monash University Method of identifying chromosomal abnormalities and prenatal diagnosis
US20050181429A1 (en) * 2003-04-03 2005-08-18 Monaliza Medical Ltd. Non-invasive prenatal genetic diagnosis using transcervical cells
US20040197832A1 (en) 2003-04-03 2004-10-07 Mor Research Applications Ltd. Non-invasive prenatal genetic diagnosis using transcervical cells
EP1778874B1 (en) 2004-07-30 2011-11-23 Adeza Biomedical Corporation Oncofetal fibronectin as a marker for cervical cancer
US20070224597A1 (en) * 2006-03-23 2007-09-27 Biocept, Inc. Isolating fetal trophoblasts
US20090286271A1 (en) 2006-05-31 2009-11-19 Karumanchi Ananth S Methods of Diagnosing and Treating Complications of Pregnancy
RU2010135816A (ru) 2008-01-30 2012-03-10 Новартис АГ (CH) Двухэтапное обогащение бесклеточной эмбриональной днк в материнской плазме
US20110027795A1 (en) * 2008-02-18 2011-02-03 Genetic Technologies Limited Cell processing and/or enrichment methods
AU2010239131A1 (en) * 2009-04-21 2011-11-17 Genetic Technologies Limited Methods for obtaining fetal genetic material
EP2909315B1 (en) 2012-10-19 2019-05-01 Wayne State University Identification and analysis of fetal trophoblast cells in cervical mucus for prenatal diagnosis

Also Published As

Publication number Publication date
WO2014062995A1 (en) 2014-04-24
CA2888746C (en) 2022-07-26
TR201908019T4 (tr) 2019-06-21
CA2888746A1 (en) 2014-04-24
JP2015533504A (ja) 2015-11-26
EP2909315A1 (en) 2015-08-26
US10344315B2 (en) 2019-07-09
ES2729182T3 (es) 2019-10-30
HK1214294A1 (zh) 2016-07-22
US20150267240A1 (en) 2015-09-24
EP2909315B1 (en) 2019-05-01
EP2909315A4 (en) 2016-04-20
JP6421123B2 (ja) 2018-11-07
IN2015DN03186A (da) 2015-10-02
AU2013331171B2 (en) 2019-05-30
AU2013331171A1 (en) 2015-05-28

Similar Documents

Publication Publication Date Title
DK2909315T3 (da) Identifikation og analyse af føtale trofoblastceller i cervixslim til prænatal diagnose
SG11201500313YA (en) Single cell analysis using sequence tags
HK1214360A1 (zh) 用於電化學分析的檢測裝置
DK3301193T3 (da) Størrelsesbaseret analyse af føtal dna-fraktion i maternelt plasma
BR112015001592A2 (pt) análise de imagem e medidas de amostras biológicas
EP2867654A4 (en) SAMPLE COLLECTION AND BIOLUMINESCENT ANALYSIS SYSTEM
SG11201506644XA (en) Cell-based tissue analysis
DK3495498T3 (da) Genekspressionsanalyse i enkeltceller
EP2693219A4 (en) Sample Analysis System and Sample Analysis Device
EP2995676A4 (en) DEVICE FOR ANALYZING CELLS AND FOR MONITORING CELL CULTURE AND METHOD FOR ANALYZING CELLS AND MONITORING CELL CULTURE USING THE SAME
EP2925234A4 (en) SPECIMEN COLLECTION DEVICE AND KIT THEREOF
DK2676139T3 (da) Fremgangsmåde til diagnosticering af cancer og diagnosekit til måling af nk celle-aktivitet
EP2918225A4 (en) BIOLOGICAL INFORMATION MEASURING DEVICE AND INPUT DEVICE USING THE SAME
HK1207515A1 (en) Method and device for acquiring neighbour cell information
GB201601244D0 (en) Flow cell for nucleic acid analysis and nucleic acid analyzer
EP2833431C0 (en) TEST BATTERY BOX AND TEST BATTERY
BR112013019162A2 (pt) método de análise e dispositivo de leitura de microarranjo
EP2751772A4 (en) LOAD PROFILE MANAGEMENT AND COST ELASTICITY ANALYSIS
DE102011100605A8 (de) Messverfahren für eine elektrochemische Energiespeichereinrichtung und Messvorrichtung
EP2894645A4 (en) ELECTROLYTIC SOLUTION AND ELECTROCHEMICAL DEVICE
DK3567099T3 (da) Nyrecellepopulationer og anvendelser deraf
EP2896350A4 (en) MEASURING PROBE AND BIOLOGICAL OPTICAL MEASURING SYSTEM
EP2851685A4 (en) SAMPLE ANALYSIS CHIP
EP2955528A4 (en) NEAR INFRARED READING DEVICE AND AMPEREMETER
EP2690444A4 (en) SAMPLE ANALYSIS DEVICE