SG11201506644XA - Cell-based tissue analysis - Google Patents

Cell-based tissue analysis

Info

Publication number
SG11201506644XA
SG11201506644XA SG11201506644XA SG11201506644XA SG11201506644XA SG 11201506644X A SG11201506644X A SG 11201506644XA SG 11201506644X A SG11201506644X A SG 11201506644XA SG 11201506644X A SG11201506644X A SG 11201506644XA SG 11201506644X A SG11201506644X A SG 11201506644XA
Authority
SG
Singapore
Prior art keywords
cell
tissue analysis
based tissue
analysis
tissue
Prior art date
Application number
SG11201506644XA
Inventor
Holger Lange
Joseph Krueger
G David Young
Trevor Johnson
Frank Voelker
Steven Potts
Original Assignee
Flagship Biosciences Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Flagship Biosciences Llc filed Critical Flagship Biosciences Llc
Publication of SG11201506644XA publication Critical patent/SG11201506644XA/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • G06V20/695—Preprocessing, e.g. image segmentation
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • G06V20/698—Matching; Classification
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N2035/00099—Characterised by type of test elements
    • G01N2035/00138—Slides
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30024—Cell structures in vitro; Tissue sections in vitro

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Theoretical Computer Science (AREA)
  • Immunology (AREA)
  • Multimedia (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Dispersion Chemistry (AREA)
  • Radiology & Medical Imaging (AREA)
  • Quality & Reliability (AREA)
  • Signal Processing (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
SG11201506644XA 2013-02-25 2014-02-25 Cell-based tissue analysis SG11201506644XA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361769049P 2013-02-25 2013-02-25
US13/934,237 US9488639B2 (en) 2013-02-25 2013-07-03 Cell-based tissue analysis
PCT/US2014/018322 WO2014131013A1 (en) 2013-02-25 2014-02-25 Cell-based tissue analysis

Publications (1)

Publication Number Publication Date
SG11201506644XA true SG11201506644XA (en) 2015-09-29

Family

ID=51391913

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201506644XA SG11201506644XA (en) 2013-02-25 2014-02-25 Cell-based tissue analysis

Country Status (5)

Country Link
US (1) US9488639B2 (en)
EP (1) EP2946190A4 (en)
JP (1) JP6222584B2 (en)
SG (1) SG11201506644XA (en)
WO (1) WO2014131013A1 (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9589172B1 (en) * 2013-02-25 2017-03-07 Flagship Biosciences, Inc. Systems and methods for interactive image analysis of digital pathology images
US9412006B1 (en) * 2013-02-25 2016-08-09 Flagship Biosciences, Inc. Continuous tissue analysis scoring scheme based on cell classifications
US9424459B1 (en) * 2013-02-25 2016-08-23 Flagship Biosciences, Inc. Computerized methods for cell-based pattern recognition
TW201520906A (en) * 2013-11-29 2015-06-01 Univ Nat Taiwan Science Tech Image registration method
WO2015124772A1 (en) 2014-02-21 2015-08-27 Ventana Medical Systems, Inc. Group sparsity model for image unmixing
US9785752B1 (en) * 2014-02-25 2017-10-10 Flagship Biosciences, Inc. Method for stratifying and selecting candidates for receiving a specific therapeutic approach
US9725766B1 (en) 2014-07-29 2017-08-08 Flagship Biosciences, Inc. Methods for measuring and reporting vascularity in a tissue sample
US9298968B1 (en) * 2014-09-12 2016-03-29 Flagship Biosciences, Inc. Digital image analysis of inflammatory cells and mediators of inflammation
JP2018505392A (en) * 2014-12-10 2018-02-22 ネオゲノミクス ラボラトリーズ， インコーポレイテッド Automated flow cytometry analysis method and system
US20180040120A1 (en) * 2014-12-29 2018-02-08 Flagship Biosciences, Inc. Methods for quantitative assessment of mononuclear cells in muscle tissue sections
CA2973418C (en) * 2015-01-31 2023-07-25 Ventana Medical Systems, Inc. Quality control of automated whole-slide analysis
AU2016214922B2 (en) 2015-02-02 2019-07-25 Stryker European Operations Limited Methods and systems for characterizing tissue of a subject
EP3054279A1 (en) * 2015-02-06 2016-08-10 St. Anna Kinderkrebsforschung e.V. Methods for classification and visualization of cellular populations on a single cell level based on microscopy images
EP3352697A4 (en) 2015-09-23 2019-06-19 Novadaq Technologies ULC Methods and systems for management of data derived from medical imaging
WO2017109860A1 (en) * 2015-12-22 2017-06-29 株式会社ニコン Image processing apparatus
EP3424019A4 (en) 2016-03-01 2019-10-23 Ventana Medical Systems, Inc. Improved image analysis algorithms using control slides
WO2017171720A1 (en) * 2016-03-29 2017-10-05 Flagship Biosciences, Inc. Digital image analysis of inflammatory cells and mediators of inflammation
EP3440629B1 (en) * 2016-04-06 2020-02-26 H. Hoffnabb-La Roche Ag Spatial index creation for ihc image analysis
WO2018005413A1 (en) * 2016-06-30 2018-01-04 Konica Minolta Laboratory U.S.A., Inc. Method and system for cell annotation with adaptive incremental learning
WO2018009202A1 (en) * 2016-07-07 2018-01-11 Flagship Biosciences Inc. Continuous tissue analysis scoring scheme based on cell classifications
US11096602B2 (en) 2016-07-29 2021-08-24 Stryker European Operations Limited Methods and systems for characterizing tissue of a subject utilizing a machine learning
JP6799146B2 (en) 2016-10-07 2020-12-09 ベンタナ メディカル システムズ， インコーポレイテッド Digital pathology system and related workflows to provide visualized slide-wide image analysis
US10504224B1 (en) * 2016-12-31 2019-12-10 Flagship Biosciences, Inc. Method for detecting immunostaining below the threshold of visual perception
WO2019009893A1 (en) * 2017-07-05 2019-01-10 Flagship Biosciences Inc. Methods for measuring and reporting vascularity in a tissue sample
US20220207895A1 (en) * 2019-04-02 2022-06-30 Deutsches Rheuma-Forschungszentrum Berlin Cytometry data analysis
EP3876193A1 (en) * 2020-03-02 2021-09-08 Euroimmun Medizinische Labordiagnostika AG Image processing method for displaying cells of multiple overall images
EP4295307A1 (en) * 2021-02-16 2023-12-27 Verily Life Sciences LLC Systems and methods for biomarker detection in digitized pathology samples

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0797069B2 (en) * 1993-05-14 1995-10-18 財団法人東京都神経科学総合研究所 Method and device for collecting and holding continuous thin section for microscope
WO2001020044A2 (en) * 1999-09-17 2001-03-22 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health & Human Services, The National Institutes Of Health Signal counting for in situ hybridization
JP2003510571A (en) * 1999-09-24 2003-03-18 ジョナサン コヘン A high-throughput system for assessing the clinical utility of molecular targets in tissue samples
WO2003059272A2 (en) 2002-01-14 2003-07-24 Henry Ford Health System Materials from bone marrow stromal cells for use in forming blood vessels and producing angiogenic and trophic factors
US7181055B2 (en) 2003-08-15 2007-02-20 Holger Lange Systems and methods for registering reflectance and fluorescence hyperspectral imagery
US7899624B2 (en) * 2005-07-25 2011-03-01 Hernani Del Mundo Cualing Virtual flow cytometry on immunostained tissue-tissue cytometer
EP2027465A2 (en) * 2006-05-17 2009-02-25 Cellumen, Inc. Method for automated tissue analysis
US8027533B2 (en) 2007-03-19 2011-09-27 Sti Medical Systems, Llc Method of automated image color calibration
US8787651B2 (en) * 2010-09-28 2014-07-22 Flagship Biosciences, LLC Methods for feature analysis on consecutive tissue sections
US8983166B2 (en) * 2011-03-23 2015-03-17 Hologic, Inc. Method for automatically seeding previously-classified images among images of objects of interest from a specimen
US20120269418A1 (en) * 2011-04-22 2012-10-25 Ge Global Research Analyzing the expression of biomarkers in cells with clusters
RU2014102672A (en) * 2011-07-28 2015-09-10 Медетект Аб METHOD FOR PRODUCING FABRIC CUTTING IMAGES

Also Published As

Publication number Publication date
WO2014131013A1 (en) 2014-08-28
EP2946190A4 (en) 2016-11-23
JP2016507759A (en) 2016-03-10
US20150004630A1 (en) 2015-01-01
US9488639B2 (en) 2016-11-08
JP6222584B2 (en) 2017-11-01
EP2946190A1 (en) 2015-11-25

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