JP6329553B2 - Ibsの診断マーカーとしての微生物バイオームに対する抗体、ストレス因子及びマスト細胞マーカー - Google Patents

Ibsの診断マーカーとしての微生物バイオームに対する抗体、ストレス因子及びマスト細胞マーカー Download PDF

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JP6329553B2
JP6329553B2 JP2015535149A JP2015535149A JP6329553B2 JP 6329553 B2 JP6329553 B2 JP 6329553B2 JP 2015535149 A JP2015535149 A JP 2015535149A JP 2015535149 A JP2015535149 A JP 2015535149A JP 6329553 B2 JP6329553 B2 JP 6329553B2
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ibs
bacterial antigen
antibody
level
markers
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JP2015533213A (ja
JP2015533213A5 (https=
Inventor
シャラット シン,
シャラット シン,
リン, ニコラス チ‐クワン
リン, ニコラス チ‐クワン
シュイ‐ロン ワン,
シュイ‐ロン ワン,
フレッド プリンセン,
フレッド プリンセン,
ステファン ウェスティン,
ステファン ウェスティン,
スティーブン ロックトン,
スティーブン ロックトン,
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Nestec SA
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Nestec SA
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/06Gastro-intestinal diseases
    • G01N2800/065Bowel diseases, e.g. Crohn, ulcerative colitis, IBS
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/60Complex ways of combining multiple protein biomarkers for diagnosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2015535149A 2012-10-05 2013-10-01 Ibsの診断マーカーとしての微生物バイオームに対する抗体、ストレス因子及びマスト細胞マーカー Expired - Fee Related JP6329553B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261710574P 2012-10-05 2012-10-05
US61/710,574 2012-10-05
US201361871853P 2013-08-29 2013-08-29
US61/871,853 2013-08-29
PCT/IB2013/059045 WO2014053996A2 (en) 2012-10-05 2013-10-01 Antibodies to microbiome, stress factors and mast cell markers as diagnostic markers for ibs

Publications (3)

Publication Number Publication Date
JP2015533213A JP2015533213A (ja) 2015-11-19
JP2015533213A5 JP2015533213A5 (https=) 2016-11-24
JP6329553B2 true JP6329553B2 (ja) 2018-05-23

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JP2015535149A Expired - Fee Related JP6329553B2 (ja) 2012-10-05 2013-10-01 Ibsの診断マーカーとしての微生物バイオームに対する抗体、ストレス因子及びマスト細胞マーカー

Country Status (9)

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US (1) US10184940B2 (https=)
EP (1) EP2904395B1 (https=)
JP (1) JP6329553B2 (https=)
CN (1) CN104884959B (https=)
AU (1) AU2013326133B2 (https=)
CA (1) CA2886991A1 (https=)
MX (1) MX360479B (https=)
SG (2) SG11201502641YA (https=)
WO (1) WO2014053996A2 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0720250D0 (en) * 2007-10-17 2007-11-28 Univ Edinburgh Immunogenic compositions containing escherichia coli h7 flagella and methods of use thereof
BR112015027591A2 (pt) * 2013-05-17 2017-07-25 Basf Se processos para a preparação de um ácido, de um cloreto e de um composto de sulfimina
SG11201509371XA (en) * 2013-05-24 2015-12-30 Nestec Sa Pathway specific markers for diagnosing irritable bowel syndrome
AU2016349703A1 (en) 2015-11-06 2018-11-01 Vetica Labs, Inc. Methods of detecting inflammatory markers and treating inflammatory conditions in companion animals
EP3421616A1 (en) * 2017-06-29 2019-01-02 Tata Consultancy Services Limited Method and system for monitoring the gut health of an individual
AU2018346255A1 (en) * 2017-10-03 2020-04-23 Seres Therapeutics, Inc. Manipulation of tryptamine metabolism
JP6533930B1 (ja) * 2018-08-23 2019-06-26 一般社団法人日本農業フロンティア開発機構 疾病評価指標算出方法、装置、システム、及び、プログラム、並びに、疾病評価指標を算出するためのモデル作成方法。
US11884958B2 (en) 2019-04-30 2024-01-30 Mayo Foundation For Medical Education And Research Assessing and treating functional gastrointestinal disorders
WO2025071560A1 (en) * 2023-09-28 2025-04-03 Rutgers, The State University Of New Jersey Methods of diagnosing b cell malignancies, detecting b cell malignancy relapse, and treating thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004048600A2 (en) * 2002-11-22 2004-06-10 Emory University Diagnostic tests and methods for diagnosing inflammatory bowel disease
US20060154276A1 (en) * 2004-05-13 2006-07-13 Prometheus Laboratories Inc. Methods of diagnosing inflammatory bowel disease
US7943328B1 (en) * 2006-03-03 2011-05-17 Prometheus Laboratories Inc. Method and system for assisting in diagnosing irritable bowel syndrome
US20100094560A1 (en) * 2006-08-15 2010-04-15 Prometheus Laboratories Inc. Methods for diagnosing irritable bowel syndrome
US20080085524A1 (en) 2006-08-15 2008-04-10 Prometheus Laboratories Inc. Methods for diagnosing irritable bowel syndrome
CN102480932B (zh) * 2009-09-01 2015-01-14 阿昂梅迪克斯公司 源于肠道共生细菌的细胞外小泡及利用其的疫苗、备选药物筛选方法
PH12012500850A1 (en) * 2009-10-30 2013-01-07 Prometheus Laboratories Inc Methods for diagnosing irritable bowel syndrome

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Publication number Publication date
CA2886991A1 (en) 2014-04-10
CN104884959B (zh) 2017-12-01
JP2015533213A (ja) 2015-11-19
MX2015004271A (es) 2015-08-14
WO2014053996A3 (en) 2014-05-30
EP2904395A2 (en) 2015-08-12
US20150346200A1 (en) 2015-12-03
WO2014053996A2 (en) 2014-04-10
CN104884959A (zh) 2015-09-02
SG10201702773QA (en) 2017-06-29
HK1213050A1 (en) 2016-06-24
EP2904395B1 (en) 2018-09-05
MX360479B (es) 2018-11-05
AU2013326133B2 (en) 2019-07-04
AU2013326133A1 (en) 2015-04-23
US10184940B2 (en) 2019-01-22
SG11201502641YA (en) 2015-05-28

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