CA2886991A1 - Antibodies to microbiome, stress factors and mast cell markers as diagnostic markers for ibs - Google Patents

Antibodies to microbiome, stress factors and mast cell markers as diagnostic markers for ibs Download PDF

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Publication number
CA2886991A1
CA2886991A1 CA2886991A CA2886991A CA2886991A1 CA 2886991 A1 CA2886991 A1 CA 2886991A1 CA 2886991 A CA2886991 A CA 2886991A CA 2886991 A CA2886991 A CA 2886991A CA 2886991 A1 CA2886991 A1 CA 2886991A1
Authority
CA
Canada
Prior art keywords
ibs
bacterial antigen
level
antigen antibody
markers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2886991A
Other languages
English (en)
French (fr)
Inventor
Sharat Singh
Nicholas Chi-Kwan Ling
Shui-long WANG
Fred Princen
Stefan Westin
Steven LOCKTON
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Societe des Produits Nestle SA
Original Assignee
Nestec SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nestec SA filed Critical Nestec SA
Publication of CA2886991A1 publication Critical patent/CA2886991A1/en
Abandoned legal-status Critical Current

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/06Gastro-intestinal diseases
    • G01N2800/065Bowel diseases, e.g. Crohn, ulcerative colitis, IBS
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/60Complex ways of combining multiple protein biomarkers for diagnosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA2886991A 2012-10-05 2013-10-01 Antibodies to microbiome, stress factors and mast cell markers as diagnostic markers for ibs Abandoned CA2886991A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261710574P 2012-10-05 2012-10-05
US61/710,574 2012-10-05
US201361871853P 2013-08-29 2013-08-29
US61/871,853 2013-08-29
PCT/IB2013/059045 WO2014053996A2 (en) 2012-10-05 2013-10-01 Antibodies to microbiome, stress factors and mast cell markers as diagnostic markers for ibs

Publications (1)

Publication Number Publication Date
CA2886991A1 true CA2886991A1 (en) 2014-04-10

Family

ID=49447585

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2886991A Abandoned CA2886991A1 (en) 2012-10-05 2013-10-01 Antibodies to microbiome, stress factors and mast cell markers as diagnostic markers for ibs

Country Status (9)

Country Link
US (1) US10184940B2 (https=)
EP (1) EP2904395B1 (https=)
JP (1) JP6329553B2 (https=)
CN (1) CN104884959B (https=)
AU (1) AU2013326133B2 (https=)
CA (1) CA2886991A1 (https=)
MX (1) MX360479B (https=)
SG (2) SG11201502641YA (https=)
WO (1) WO2014053996A2 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0720250D0 (en) * 2007-10-17 2007-11-28 Univ Edinburgh Immunogenic compositions containing escherichia coli h7 flagella and methods of use thereof
BR112015027591A2 (pt) * 2013-05-17 2017-07-25 Basf Se processos para a preparação de um ácido, de um cloreto e de um composto de sulfimina
SG11201509371XA (en) * 2013-05-24 2015-12-30 Nestec Sa Pathway specific markers for diagnosing irritable bowel syndrome
AU2016349703A1 (en) 2015-11-06 2018-11-01 Vetica Labs, Inc. Methods of detecting inflammatory markers and treating inflammatory conditions in companion animals
EP3421616A1 (en) * 2017-06-29 2019-01-02 Tata Consultancy Services Limited Method and system for monitoring the gut health of an individual
AU2018346255A1 (en) * 2017-10-03 2020-04-23 Seres Therapeutics, Inc. Manipulation of tryptamine metabolism
JP6533930B1 (ja) * 2018-08-23 2019-06-26 一般社団法人日本農業フロンティア開発機構 疾病評価指標算出方法、装置、システム、及び、プログラム、並びに、疾病評価指標を算出するためのモデル作成方法。
US11884958B2 (en) 2019-04-30 2024-01-30 Mayo Foundation For Medical Education And Research Assessing and treating functional gastrointestinal disorders
WO2025071560A1 (en) * 2023-09-28 2025-04-03 Rutgers, The State University Of New Jersey Methods of diagnosing b cell malignancies, detecting b cell malignancy relapse, and treating thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004048600A2 (en) * 2002-11-22 2004-06-10 Emory University Diagnostic tests and methods for diagnosing inflammatory bowel disease
US20060154276A1 (en) * 2004-05-13 2006-07-13 Prometheus Laboratories Inc. Methods of diagnosing inflammatory bowel disease
US7943328B1 (en) * 2006-03-03 2011-05-17 Prometheus Laboratories Inc. Method and system for assisting in diagnosing irritable bowel syndrome
US20100094560A1 (en) * 2006-08-15 2010-04-15 Prometheus Laboratories Inc. Methods for diagnosing irritable bowel syndrome
US20080085524A1 (en) 2006-08-15 2008-04-10 Prometheus Laboratories Inc. Methods for diagnosing irritable bowel syndrome
CN102480932B (zh) * 2009-09-01 2015-01-14 阿昂梅迪克斯公司 源于肠道共生细菌的细胞外小泡及利用其的疫苗、备选药物筛选方法
PH12012500850A1 (en) * 2009-10-30 2013-01-07 Prometheus Laboratories Inc Methods for diagnosing irritable bowel syndrome

Also Published As

Publication number Publication date
CN104884959B (zh) 2017-12-01
JP2015533213A (ja) 2015-11-19
MX2015004271A (es) 2015-08-14
JP6329553B2 (ja) 2018-05-23
WO2014053996A3 (en) 2014-05-30
EP2904395A2 (en) 2015-08-12
US20150346200A1 (en) 2015-12-03
WO2014053996A2 (en) 2014-04-10
CN104884959A (zh) 2015-09-02
SG10201702773QA (en) 2017-06-29
HK1213050A1 (en) 2016-06-24
EP2904395B1 (en) 2018-09-05
MX360479B (es) 2018-11-05
AU2013326133B2 (en) 2019-07-04
AU2013326133A1 (en) 2015-04-23
US10184940B2 (en) 2019-01-22
SG11201502641YA (en) 2015-05-28

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20161004

FZDE Discontinued

Effective date: 20201207