JP6309508B2 - 前駆イオンの同定方法 - Google Patents

前駆イオンの同定方法 Download PDF

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Publication number
JP6309508B2
JP6309508B2 JP2015512116A JP2015512116A JP6309508B2 JP 6309508 B2 JP6309508 B2 JP 6309508B2 JP 2015512116 A JP2015512116 A JP 2015512116A JP 2015512116 A JP2015512116 A JP 2015512116A JP 6309508 B2 JP6309508 B2 JP 6309508B2
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mass
ion
fragment
ions
precursor
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Japanese (ja)
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JP2015523550A (ja
JP2015523550A5 (enExample
Inventor
ジェイソン リー ワイルドグース，
ジェイソン リー ワイルドグース，
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マイクロマス ユーケー リミテッド
マイクロマス ユーケー リミテッド
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    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H01J49/0045—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H01J49/0031—Step by step routines describing the use of the apparatus
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H01J49/0036—Step by step routines describing the handling of the data generated during a measurement
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H01J49/0045—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction
    • H01J49/005—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction by collision with gas, e.g. by introducing gas or by accelerating ions with an electric field
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/40—Time-of-flight spectrometers

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  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
JP2015512116A 2012-05-18 2013-05-09 前駆イオンの同定方法 Active JP6309508B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB1208961.1A GB201208961D0 (en) 2012-05-18 2012-05-18 2 dimensional MSMS
GB1208961.1 2012-05-18
US201261649998P 2012-05-22 2012-05-22
US61/649,998 2012-05-22
PCT/GB2013/051199 WO2013171459A2 (en) 2012-05-18 2013-05-09 Method of identifying precursor ions

Publications (3)

Publication Number Publication Date
JP2015523550A JP2015523550A (ja) 2015-08-13
JP2015523550A5 JP2015523550A5 (enExample) 2017-03-16
JP6309508B2 true JP6309508B2 (ja) 2018-04-11

Family

ID=46546450

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015512116A Active JP6309508B2 (ja) 2012-05-18 2013-05-09 前駆イオンの同定方法

Country Status (6)

Country Link
US (2) US9460902B2 (enExample)
EP (2) EP3926659B1 (enExample)
JP (1) JP6309508B2 (enExample)
CA (1) CA2873610C (enExample)
GB (2) GB201208961D0 (enExample)
WO (1) WO2013171459A2 (enExample)

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DE112015002258B4 (de) * 2014-05-13 2023-09-21 Micromass Uk Limited Mehrdimensionale Ionentrennung
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EP3155638B1 (en) * 2014-06-13 2023-09-20 Waters Technologies Corporation Analysis of complex biological matrices through targeting and advanced precursor and product ion alignment
CN106463339B (zh) * 2014-06-16 2018-06-15 株式会社岛津制作所 Ms/ms型质谱分析方法以及ms/ms型质谱分析装置
WO2016055888A1 (en) * 2014-10-08 2016-04-14 Dh Technologies Development Pte. Ltd. Improving ida spectral output for database searches
JP6698668B2 (ja) * 2015-02-05 2020-05-27 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド 断片化エネルギーを切り替えながらの幅広い四重極ｒｆ窓の高速スキャニング
CN111710588B (zh) * 2015-04-23 2023-09-26 英国质谱公司 在离子阱中分离离子
CN109075012B (zh) 2016-04-14 2021-01-26 英国质谱公司 二维msms
WO2018020363A1 (en) 2016-07-25 2018-02-01 Dh Technologies Development Pte. Ltd. Systems and methods for identifying precursor and product ion pairs in scanning swath data
WO2018154400A1 (en) * 2017-02-22 2018-08-30 Dh Technologies Development Pte. Ltd. Physical isolation of adducts and other complicating factors in precursor ion selection for ida
GB2563565B (en) 2017-04-13 2022-05-11 Micromass Ltd Mass spectrometry with increased duty cycle
WO2020049694A1 (ja) * 2018-09-06 2020-03-12 株式会社島津製作所 四重極質量分析装置
US10832897B2 (en) * 2018-10-19 2020-11-10 Thermo Finnigan Llc Methods and devices for high-throughput data independent analysis for mass spectrometry using parallel arrays of cells
WO2020240506A1 (en) 2019-05-31 2020-12-03 Dh Technologies Development Pte. Ltd. Method for real time encoding of scanning swath data and probabilistic framework for precursor inference
JP7762203B2 (ja) 2020-11-19 2025-10-29 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド 質量分析の堅牢性を強化するためにバンドパスフィルタリング衝突セルを使用して高強度イオンビームのｍｓ／ｍｓを実施する方法
US20240258091A1 (en) 2021-06-09 2024-08-01 Dh Technologies Development Pte. Ltd. Enhanced Q1 Mass Segregation in Scanning SWATH
WO2023002282A1 (en) 2021-07-23 2023-01-26 Dh Technologies Development Pte. Ltd. Preventing errors in processing and interpreting mass spectrometry results
CN117795643A (zh) 2021-08-05 2024-03-29 Dh科技发展私人贸易有限公司 Tof-ms中的空间电荷减少
US20240404813A1 (en) 2021-08-26 2024-12-05 Dh Technologies Development Pte. Ltd. Method for enhancing information in dda mass spectrometry
WO2023037248A1 (en) 2021-09-08 2023-03-16 Dh Technologies Development Pte. Ltd. Identification of changing pathways or disease indicators through cluster analysis
WO2023057925A1 (en) 2021-10-05 2023-04-13 Dh Technologies Development Pte. Ltd. Methods for enhancing complete data extraction of dia data
CN118556276A (zh) 2021-11-19 2024-08-27 Dh科技发展私人贸易有限公司 用于使用模拟检测系统进行降噪和离子速率估计的方法
EP4473537A1 (en) 2022-02-04 2024-12-11 DH Technologies Development Pte. Ltd. Compound identification using a mass spectrum
EP4508650A1 (en) 2022-04-12 2025-02-19 DH Technologies Development Pte. Ltd. Library search using deep learning based spectral compression
US20250191673A1 (en) 2022-04-12 2025-06-12 Dh Technologies Development Pte. Ltd. Scoring of Whole Protein MSMS Spectra Based on a Bond Relevance Score
US20250259697A1 (en) 2022-04-12 2025-08-14 Dh Technologies Development Pte. Ltd. Single Panel Representation of Multiple Charge Evidence Linked to a Bond in the Protein
WO2024075065A1 (en) 2022-10-06 2024-04-11 Dh Technologies Development Pte. Ltd. Creation of realistic ms/ms spectra for putative designer drugs
WO2024075058A1 (en) 2022-10-06 2024-04-11 Dh Technologies Development Pte. Ltd. Reducing data complexity for subsequent rt alignment
WO2024121697A1 (en) 2022-12-07 2024-06-13 Dh Technologies Development Pte. Ltd. De novo sequencing of dna
WO2024150129A1 (en) 2023-01-09 2024-07-18 Dh Technologies Development Pte. Ltd. Sequencing of morpholino oligomers using electron capture dissociation
WO2024194801A1 (en) * 2023-03-22 2024-09-26 Dh Technologies Development Pte. Ltd. Multidimensional variable scanning swath mass spectrometry

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GB0909289D0 (en) * 2009-05-29 2009-07-15 Micromass Ltd Method of processing mass spectral data
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JP5454484B2 (ja) * 2011-01-31 2014-03-26 株式会社島津製作所 三連四重極型質量分析装置
GB201208961D0 (en) * 2012-05-18 2012-07-04 Micromass Ltd 2 dimensional MSMS
US10615014B2 (en) * 2013-11-12 2020-04-07 Micromass Uk Limited Data dependent MS/MS analysis

Also Published As

Publication number Publication date
EP2850636B1 (en) 2021-09-01
GB2504373A (en) 2014-01-29
CA2873610C (en) 2020-03-24
US9460902B2 (en) 2016-10-04
EP3926659A1 (en) 2021-12-22
JP2015523550A (ja) 2015-08-13
WO2013171459A2 (en) 2013-11-21
CA2873610A1 (en) 2013-11-21
GB2504373B (en) 2017-01-25
GB201208961D0 (en) 2012-07-04
EP3926659B1 (en) 2025-07-30
US10068754B2 (en) 2018-09-04
US20150136969A1 (en) 2015-05-21
GB201308297D0 (en) 2013-06-12
WO2013171459A3 (en) 2014-06-26
EP2850636A2 (en) 2015-03-25
US20170125224A1 (en) 2017-05-04

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