JP6293392B1 - 生体観察システム - Google Patents
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- 230000035945 sensitivity Effects 0.000 claims abstract description 20
- 230000003287 optical effect Effects 0.000 claims abstract description 16
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- 238000003384 imaging method Methods 0.000 claims description 38
- 238000010521 absorption reaction Methods 0.000 claims description 10
- 238000000034 method Methods 0.000 claims description 8
- 102000001554 Hemoglobins Human genes 0.000 claims description 6
- 108010054147 Hemoglobins Proteins 0.000 claims description 6
- 238000000926 separation method Methods 0.000 description 31
- 210000004204 blood vessel Anatomy 0.000 description 24
- 230000000875 corresponding effect Effects 0.000 description 21
- 238000003780 insertion Methods 0.000 description 10
- 230000037431 insertion Effects 0.000 description 10
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- 230000002596 correlated effect Effects 0.000 description 5
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- 230000007423 decrease Effects 0.000 description 2
- 230000006866 deterioration Effects 0.000 description 2
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- 239000004973 liquid crystal related substance Substances 0.000 description 1
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/1459—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
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- A61B1/00009—Operational features of endoscopes characterised by electronic signal processing of image signals during a use of endoscope
- A61B1/000094—Operational features of endoscopes characterised by electronic signal processing of image signals during a use of endoscope extracting biological structures
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- A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
- A61B1/042—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances characterised by a proximal camera, e.g. a CCD camera
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- A61B1/05—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances characterised by the image sensor, e.g. camera, being in the distal end portion
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- A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
- A61B1/0638—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements providing two or more wavelengths
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- A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
- A61B5/0086—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters using infrared radiation
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- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
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- A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
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- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/02007—Evaluating blood vessel condition, e.g. elasticity, compliance
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- A—HUMAN NECESSITIES
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/026—Measuring blood flow
- A61B5/0261—Measuring blood flow using optical means, e.g. infrared light
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H30/00—ICT specially adapted for the handling or processing of medical images
- G16H30/40—ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Spectroscopy & Molecular Physics (AREA)
- Signal Processing (AREA)
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- Instruments For Viewing The Inside Of Hollow Bodies (AREA)
Abstract
Description
Claims (8)
- 可視域における赤色域に属し、かつ、ヘモグロビンの吸収特性において極大値を示す波長と極小値を示す波長との間に属する狭帯域光である第1の波長帯域の光と、前記第1の波長帯域よりも長波長側に属し、ヘモグロビンの吸収特性における吸収係数が前記第1の波長帯域よりも低く、かつ、生体組織の散乱特性が抑制された狭帯域光である第2の波長帯域の光と、前記第1の波長帯域よりも短波長側に属する光である第3の波長帯域の光と、を出射することができるように構成された光源部と、
前記第1の波長帯域の光と、前記第2の波長帯域の光と、前記第3の波長帯域の光と、を含む照明光を前記光源部から出射させるための制御を行うように構成された制御部と、
前記第1の波長帯域及び前記第3の波長帯域に感度を有するように構成された第1の撮像素子と、
前記第2の波長帯域に感度を有するように構成された第2の撮像素子と、
前記照明光が照射された被写体からの反射光が入射された際に、前記被写体からの反射光に含まれる前記第1の波長帯域の光及び前記第3の波長帯域の光を前記第1の撮像素子側へ出射するとともに、前記被写体からの反射光に含まれる前記第2の波長帯域の光を前記第2の撮像素子側へ出射するように構成された分光光学系と、
を有することを特徴とする生体観察システム。 - 前記第1の波長帯域の光を前記第1の撮像素子で撮像して得られる第1の画像を表示装置の緑色に対応する第1のチャンネルに割り当て、前記第2の波長帯域の光を前記第2の撮像素子で撮像して得られる第2の画像を前記表示装置の赤色に対応する第2のチャンネルに割り当て、前記第3の波長帯域の光を前記第1の撮像素子で撮像して得られる第3の画像を表示装置の青色に対応する第3のチャンネルに割り当てることにより観察画像を生成して前記表示装置へ出力するように構成された観察画像生成部をさらに有する
ことを特徴とする請求項1に記載の生体観察システム。 - 前記観察画像生成部による前記観察画像の生成が行われる前に、前記第1の画像の解像度と、前記第2の画像の解像度と、前記第3の画像の解像度と、を一致させるための処理を行うように構成された解像度調整部をさらに有する
ことを特徴とする請求項2に記載の生体観察システム。 - 前記解像度調整部は、前記第1の画像の解像度及び前記第3の画像の解像度を前記第2の画像の解像度まで上昇させるための画素補間処理を行う
ことを特徴とする請求項3に記載の生体観察システム。 - 前記解像度調整部は、前記第2の画像の解像度を前記第1の画像の解像度または前記第3の画像の解像度まで低下させるための画素加算処理を行う
ことを特徴とする請求項3に記載の生体観察システム。 - 前記分光光学系は、前記被写体からの反射光に含まれる前記第1の波長帯域の光及び前記第3の波長帯域の光を前記第1の撮像素子側へ透過させるとともに、前記被写体からの反射光に含まれる前記第2の波長帯域の光を前記第2の撮像素子側へ反射するように構成されたダイクロイックミラーである
ことを特徴とする請求項1に記載の生体観察システム。 - 前記第1の波長帯域の光の中心波長が600nm付近に設定され、前記第2の波長帯域の光の中心波長が800nm付近に設定され、かつ、前記第3の波長帯域の光の中心波長が460nm付近に設定されている
ことを特徴とする請求項1に記載の生体観察システム。 - 前記光源部は、青色域の光を前記第3の波長帯域の光として出射することができるとともに、緑色域の光を第4の波長帯域の光として出射することができるように構成されており、
前記制御部は、前記照明光の代わりに、前記第1の波長帯域の光と、前記第3の波長帯域の光と、前記第4の波長帯域の光と、を含む白色光を前記光源部から出射させるための制御を行うことができるように構成されており、
前記第1の撮像素子は、前記第1の波長帯域、前記第3の波長帯域、及び、前記第4の波長帯域に感度を有するように構成されており、
前記分光光学系は、前記照明光の代わりに前記白色光が照射された前記被写体からの反射光が入射された際に、前記被写体からの反射光に含まれる前記第1の波長帯域の光、前記第3の波長帯域の光及び前記第4の波長帯域の光を前記第1の撮像素子側へ出射するように構成されている
ことを特徴とする請求項1に記載の生体観察システム。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2016100593 | 2016-05-19 | ||
JP2016100593 | 2016-05-19 | ||
PCT/JP2017/008107 WO2017199535A1 (ja) | 2016-05-19 | 2017-03-01 | 生体観察システム |
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JP6293392B1 true JP6293392B1 (ja) | 2018-03-14 |
JPWO2017199535A1 JPWO2017199535A1 (ja) | 2018-05-31 |
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JP2017555606A Active JP6293392B1 (ja) | 2016-05-19 | 2017-03-01 | 生体観察システム |
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US (1) | US20190008423A1 (ja) |
JP (1) | JP6293392B1 (ja) |
CN (1) | CN108778088B (ja) |
DE (1) | DE112017002547T5 (ja) |
WO (1) | WO2017199535A1 (ja) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
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JP6947047B2 (ja) * | 2018-01-16 | 2021-10-13 | トヨタ自動車株式会社 | 燃料電池用セパレータ及びその製造方法 |
JP7059353B2 (ja) * | 2018-03-05 | 2022-04-25 | オリンパス株式会社 | 内視鏡システム |
JP2019165855A (ja) * | 2018-03-22 | 2019-10-03 | ソニー・オリンパスメディカルソリューションズ株式会社 | 内視鏡装置及び医療用撮像装置 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63167577A (ja) * | 1986-12-27 | 1988-07-11 | Olympus Optical Co Ltd | 撮像装置 |
US20090236541A1 (en) * | 2008-03-24 | 2009-09-24 | General Electric Company | System and Methods for Optical Imaging |
JP2011167337A (ja) * | 2010-02-18 | 2011-09-01 | Fujifilm Corp | 画像取得方法および画像撮像装置 |
WO2013145409A1 (ja) * | 2012-03-30 | 2013-10-03 | オリンパスメディカルシステムズ株式会社 | 内視鏡装置 |
WO2013145410A1 (ja) * | 2012-03-30 | 2013-10-03 | オリンパスメディカルシステムズ株式会社 | 内視鏡装置 |
JP2015029841A (ja) * | 2013-08-06 | 2015-02-16 | 三菱電機エンジニアリング株式会社 | 撮像装置および撮像方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
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US7179222B2 (en) * | 1996-11-20 | 2007-02-20 | Olympus Corporation | Fluorescent endoscope system enabling simultaneous achievement of normal light observation based on reflected light and fluorescence observation based on light with wavelengths in infrared spectrum |
US6832009B1 (en) * | 1999-09-24 | 2004-12-14 | Zoran Corporation | Method and apparatus for improved image interpolation |
JP5405373B2 (ja) * | 2010-03-26 | 2014-02-05 | 富士フイルム株式会社 | 電子内視鏡システム |
JP5095786B2 (ja) * | 2010-08-09 | 2012-12-12 | 東京エレクトロン株式会社 | 半導体製造方法 |
JP2016100593A (ja) | 2014-11-26 | 2016-05-30 | 株式会社Flosfia | 結晶性積層構造体 |
-
2017
- 2017-03-01 WO PCT/JP2017/008107 patent/WO2017199535A1/ja active Application Filing
- 2017-03-01 DE DE112017002547.8T patent/DE112017002547T5/de not_active Withdrawn
- 2017-03-01 CN CN201780018240.6A patent/CN108778088B/zh active Active
- 2017-03-01 JP JP2017555606A patent/JP6293392B1/ja active Active
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2018
- 2018-09-14 US US16/131,161 patent/US20190008423A1/en not_active Abandoned
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63167577A (ja) * | 1986-12-27 | 1988-07-11 | Olympus Optical Co Ltd | 撮像装置 |
US20090236541A1 (en) * | 2008-03-24 | 2009-09-24 | General Electric Company | System and Methods for Optical Imaging |
JP2011167337A (ja) * | 2010-02-18 | 2011-09-01 | Fujifilm Corp | 画像取得方法および画像撮像装置 |
WO2013145409A1 (ja) * | 2012-03-30 | 2013-10-03 | オリンパスメディカルシステムズ株式会社 | 内視鏡装置 |
WO2013145410A1 (ja) * | 2012-03-30 | 2013-10-03 | オリンパスメディカルシステムズ株式会社 | 内視鏡装置 |
JP2015029841A (ja) * | 2013-08-06 | 2015-02-16 | 三菱電機エンジニアリング株式会社 | 撮像装置および撮像方法 |
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Publication number | Publication date |
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CN108778088B (zh) | 2021-03-19 |
CN108778088A (zh) | 2018-11-09 |
WO2017199535A1 (ja) | 2017-11-23 |
US20190008423A1 (en) | 2019-01-10 |
JPWO2017199535A1 (ja) | 2018-05-31 |
DE112017002547T5 (de) | 2019-02-21 |
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