JP6286536B2 - 新規オキサゾリジノン抗菌化合物 - Google Patents

新規オキサゾリジノン抗菌化合物 Download PDF

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Publication number
JP6286536B2
JP6286536B2 JP2016526946A JP2016526946A JP6286536B2 JP 6286536 B2 JP6286536 B2 JP 6286536B2 JP 2016526946 A JP2016526946 A JP 2016526946A JP 2016526946 A JP2016526946 A JP 2016526946A JP 6286536 B2 JP6286536 B2 JP 6286536B2
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Japan
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compound
formula
ppm
methyl
acetamide
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English (en)
Japanese (ja)
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JP2016535039A5 (https=
JP2016535039A (ja
Inventor
ラグー ミトラ アッラ
ラグー ミトラ アッラ
アジェイ クマール デュビー
アジェイ クマール デュビー
シュリーニバス レディ マレパリ
シュリーニバス レディ マレパリ
ラーマクリシュナ レディ ポンギラティ
ラーマクリシュナ レディ ポンギラティ
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Lee Pharma Ltd
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Lee Pharma Ltd
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2016526946A 2013-11-08 2014-07-28 新規オキサゾリジノン抗菌化合物 Expired - Fee Related JP6286536B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IN5063/CHE/2013 2013-11-08
IN5063CH2013 2013-11-08
IN2254CH2014 2014-05-05
IN2254/CHE/2014 2014-05-05
PCT/IN2014/000497 WO2015068173A1 (en) 2013-11-08 2014-07-28 Novel oxazolidinone antibacterial compound

Publications (3)

Publication Number Publication Date
JP2016535039A JP2016535039A (ja) 2016-11-10
JP2016535039A5 JP2016535039A5 (https=) 2017-08-17
JP6286536B2 true JP6286536B2 (ja) 2018-02-28

Family

ID=53040992

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016526946A Expired - Fee Related JP6286536B2 (ja) 2013-11-08 2014-07-28 新規オキサゾリジノン抗菌化合物

Country Status (6)

Country Link
US (1) US9573910B2 (https=)
EP (1) EP3065740B1 (https=)
JP (1) JP6286536B2 (https=)
CN (1) CN105705147B (https=)
ES (1) ES2699001T3 (https=)
WO (1) WO2015068173A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117597337A (zh) * 2021-05-03 2024-02-23 迪斯库瓦有限公司 抗菌化合物的制备方法
CN115707685A (zh) * 2021-08-20 2023-02-21 中国石油化工股份有限公司 一种制备胺-环氧卤丙烷聚合单体的方法及产物和系统
CN114230547A (zh) * 2021-12-29 2022-03-25 江苏广域化学有限公司 取代苯甲醛缩醇的合成方法
CN116919954A (zh) * 2023-05-22 2023-10-24 成都大学 噁唑烷酮类化合物在制备抑制细菌群体感应的药物中的应用
CN118515624B (zh) * 2024-04-29 2025-01-24 聊城金歌合成材料有限公司 一种含三氟甲基多取代恶唑烷-4-酮的合成方法及应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1260948A (en) * 1984-12-05 1989-09-26 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl benzene derivatives useful as antibacterial agents
US5688792A (en) * 1994-08-16 1997-11-18 Pharmacia & Upjohn Company Substituted oxazine and thiazine oxazolidinone antimicrobials
MY115155A (en) * 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.
KR20010015910A (ko) * 1998-01-23 2001-02-26 로렌스 티. 마이젠헬더 옥사졸리디논 조합 라이브러리, 조성물 및 제조 방법
JPH11322729A (ja) * 1998-03-09 1999-11-24 Hokuriku Seiyaku Co Ltd ジチオカルバミド酸誘導体
BR0111280A (pt) * 2000-06-05 2003-06-10 Dong A Pharm Co Ltd Novos derivados de oxazolidinona e um processo para a preparação dos mesmos
CN1155585C (zh) * 2001-12-19 2004-06-30 中国医学科学院医药生物技术研究所 3,5－取代噁唑烷酮衍生物及其制备方法和应用
TW200302095A (en) * 2002-01-25 2003-08-01 Upjohn Co Oxazolidinone cotherapy
EP2141161A1 (en) * 2008-07-01 2010-01-06 Ferrer Internacional, S.A. 3-cyanopyrrolidinyl-phenyl-oxazolidinones as antibacterial agents
EP2163547A1 (en) 2008-09-16 2010-03-17 Unión Químico Farmacéutica, S.A. (UQUIFA) Process for the preparation of an oxazolidinone antibacterial agent and intermediates thereof
WO2015068171A1 (en) 2013-11-08 2015-05-14 Lee Pharma Limited Novel oxazolidinone compounds

Also Published As

Publication number Publication date
EP3065740A1 (en) 2016-09-14
US20160272597A1 (en) 2016-09-22
CN105705147A (zh) 2016-06-22
ES2699001T3 (es) 2019-02-06
EP3065740A4 (en) 2017-04-19
JP2016535039A (ja) 2016-11-10
WO2015068173A1 (en) 2015-05-14
EP3065740B1 (en) 2018-08-22
CN105705147B (zh) 2019-06-28
US9573910B2 (en) 2017-02-21

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