JP6286421B2 - サパシタビン及びセリシクリブの投与レジメン - Google Patents
サパシタビン及びセリシクリブの投与レジメン Download PDFInfo
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- JP6286421B2 JP6286421B2 JP2015512121A JP2015512121A JP6286421B2 JP 6286421 B2 JP6286421 B2 JP 6286421B2 JP 2015512121 A JP2015512121 A JP 2015512121A JP 2015512121 A JP2015512121 A JP 2015512121A JP 6286421 B2 JP6286421 B2 JP 6286421B2
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- sapacitabine
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- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- A—HUMAN NECESSITIES
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Landscapes
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| WO2019084010A1 (en) * | 2017-10-26 | 2019-05-02 | Emory University | MCL-1 INHIBITORS, COMPOSITIONS AND USES IN CANCER CARE |
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| PL2307002T3 (pl) | 2008-06-09 | 2013-05-31 | Cyclacel Ltd | Kombinacje sapacytabiny lub cndac z inhibitorami metylotransferazy dna, takimi jak decytabina i prokaina |
| PL2696878T3 (pl) | 2011-04-14 | 2020-01-31 | Cyclacel Limited | Schemat dawkowania dla sapacytabiny i decytabiny w kombinacji do leczenia ostrej białaczki szpikowej |
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| US20150164933A1 (en) | 2015-06-18 |
| EP2874631A1 (en) | 2015-05-27 |
| US9872874B2 (en) | 2018-01-23 |
| JP2015516459A (ja) | 2015-06-11 |
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