JP6285921B2 - 超音波血栓溶解療法を用いたクモ膜下血腫の治療、並びに関連する装置、システム、及び方法 - Google Patents

超音波血栓溶解療法を用いたクモ膜下血腫の治療、並びに関連する装置、システム、及び方法 Download PDF

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JP6285921B2
JP6285921B2 JP2015517277A JP2015517277A JP6285921B2 JP 6285921 B2 JP6285921 B2 JP 6285921B2 JP 2015517277 A JP2015517277 A JP 2015517277A JP 2015517277 A JP2015517277 A JP 2015517277A JP 6285921 B2 JP6285921 B2 JP 6285921B2
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subarachnoid
module
hematoma
thrombolytic agent
delivery
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JP2015519970A (ja
JP2015519970A5 (enExample
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ダブリュー． ニューウェル，デイビッド
ダブリュー． ニューウェル，デイビッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N7/02—Localised ultrasound hyperthermia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/22—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/22004—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/10—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/06—Measuring blood flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/08—Clinical applications
    • A61B8/0808—Clinical applications for diagnosis of the brain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/48—Diagnostic techniques
    • A61B8/488—Diagnostic techniques involving Doppler signals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N2007/0004—Applications of ultrasound therapy
    • A61N2007/0021—Neural system treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N2007/0052—Ultrasound therapy using the same transducer for therapy and imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N2007/0078—Ultrasound therapy with multiple treatment transducers

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pathology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Mechanical Engineering (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Vascular Medicine (AREA)
  • Surgical Instruments (AREA)
JP2015517277A 2012-06-13 2013-05-24 超音波血栓溶解療法を用いたクモ膜下血腫の治療、並びに関連する装置、システム、及び方法 Expired - Fee Related JP6285921B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261659269P 2012-06-13 2012-06-13
US61/659,269 2012-06-13
PCT/US2013/042744 WO2013188084A1 (en) 2012-06-13 2013-05-24 Treatment of subarachnoid hematoma using sonothrombolysis and associated devices, systems and methods

Publications (3)

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JP2015519970A JP2015519970A (ja) 2015-07-16
JP2015519970A5 JP2015519970A5 (enExample) 2016-07-07
JP6285921B2 true JP6285921B2 (ja) 2018-02-28

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JP2015517277A Expired - Fee Related JP6285921B2 (ja) 2012-06-13 2013-05-24 超音波血栓溶解療法を用いたクモ膜下血腫の治療、並びに関連する装置、システム、及び方法

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US (2) US9808653B2 (enExample)
EP (1) EP2861300A4 (enExample)
JP (1) JP6285921B2 (enExample)
WO (1) WO2013188084A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11191886B2 (en) 2013-06-14 2021-12-07 The Cleveland Clinic Foundation Motion-assisted systems, devices and methods for minimizing obstruction of medical devices
US10391285B2 (en) * 2013-06-14 2019-08-27 The Cleveland Clinic Foundation Motion-assisted systems, devices and methods for minimizing obstruction of medical devices
WO2015003154A1 (en) 2013-07-03 2015-01-08 Histosonics, Inc. Articulating arm limiter for cavitational ultrasound therapy system
US10780298B2 (en) 2013-08-22 2020-09-22 The Regents Of The University Of Michigan Histotripsy using very short monopolar ultrasound pulses
EP3218058B1 (en) 2014-11-14 2022-07-20 Koninklijke Philips N.V. Ultrasound device for sonothrombolysis therapy
CN108348772B (zh) 2015-06-24 2020-03-03 美国密歇根州立大学试剂中心 用于治疗脑组织的组织摧毁术治疗系统和方法
WO2018027298A1 (en) * 2016-08-12 2018-02-15 Gand François Portable alzheimer detector
EP3534777B1 (en) 2016-11-01 2024-03-27 Nihon Kohden Corporation Apparatus to screen for and monitor cerebrovascular stenosis
EP3886737A4 (en) 2018-11-28 2022-08-24 Histosonics, Inc. HISTOTRIPSY SYSTEMS AND METHODS
EP3923814B1 (fr) * 2019-02-15 2025-11-19 Boysset, Max Pièce d'habillement pour contrôle de cellules
EP4096782A4 (en) 2020-01-28 2024-02-14 The Regents Of The University Of Michigan SYSTEMS AND METHODS FOR HISTOTRIPSIA IMMUNOSENSITIZATION
IL300851A (en) 2020-08-27 2023-04-01 Univ Michigan Regents Ultrasonic transducer with transmit-receive capability for focused ultrasound
AU2023366591A1 (en) 2022-10-28 2025-04-24 Histosonics, Inc. Histotripsy systems and methods
AU2024257180A1 (en) 2023-04-20 2025-09-18 Histosonics, Inc. Histotripsy systems and associated methods including user interfaces and workflows for treatment planning and therapy

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03222961A (ja) * 1990-01-29 1991-10-01 Olympus Optical Co Ltd 溶解治療装置
CA2048120A1 (en) * 1990-08-06 1992-02-07 William J. Drasler Thrombectomy method and device
JP3300419B2 (ja) * 1991-08-21 2002-07-08 株式会社東芝 血栓溶解治療装置
US6635017B1 (en) * 2000-02-09 2003-10-21 Spentech, Inc. Method and apparatus combining diagnostic ultrasound with therapeutic ultrasound to enhance thrombolysis
US6733450B1 (en) 2000-07-27 2004-05-11 Texas Systems, Board Of Regents Therapeutic methods and apparatus for use of sonication to enhance perfusion of tissue
US20040209307A1 (en) * 2001-08-20 2004-10-21 Biosite Incorporated Diagnostic markers of stroke and cerebral injury and methods of use thereof
JP2004024668A (ja) * 2002-06-27 2004-01-29 Hiroshi Furuhata 経頭蓋超音波治療装置
AU2003290806A1 (en) * 2002-11-15 2004-06-15 The Government Of The United States As Represented By The Secretary Of The Department Of Health And Human Services Variable curve catheter
US7662098B2 (en) * 2003-01-31 2010-02-16 Hitachi Medical Corporation Ultrasonic probe and ultrasonic device
US20040215067A1 (en) * 2003-04-24 2004-10-28 Stiger Mark L. Flow sensor device for endoscopic third ventriculostomy
CA2535981C (en) * 2003-09-08 2014-10-28 Board Of Trustees Of The University Of Arkansas Ultrasound apparatus and method for augmented clot lysis
US8409099B2 (en) * 2004-08-26 2013-04-02 Insightec Ltd. Focused ultrasound system for surrounding a body tissue mass and treatment method
US8112154B2 (en) 2005-04-13 2012-02-07 The Cleveland Clinic Foundation Systems and methods for neuromodulation using pre-recorded waveforms
US20110319927A1 (en) * 2005-06-24 2011-12-29 Penumbra, Inc. Methods and apparatus for removing blood clots from intracranial aneurysms
US20110313328A1 (en) * 2005-06-24 2011-12-22 Penumbra, Inc. Methods and apparatus for dissolving blockages in intracranial catheters
US20080089848A1 (en) * 2006-10-11 2008-04-17 Dimauro Thomas Intrathecal injection of microbubbles
WO2008102563A1 (ja) * 2007-02-23 2008-08-28 Next21 K.K. 血管攣縮の治療剤又は予防剤
US20080294089A1 (en) * 2007-06-06 2008-11-27 Biovaluation & Analysis, Inc. Dendritic Polymers for Use in Acoustically Mediated Intracellular Drug Delivery in vivo
ES2471118T3 (es) 2007-06-22 2014-06-25 Ekos Corporation Método y aparato para el tratamiento de hemorragias intracraneales
CA2735140A1 (en) * 2008-09-19 2010-03-25 Physiosonics, Inc. Acoustic palpation using non-invasive ultrasound techniques to identify and localize tissue eliciting biological responses
US8425424B2 (en) * 2008-11-19 2013-04-23 Inightee Ltd. Closed-loop clot lysis
EP2608730B1 (en) 2010-08-27 2019-07-24 Ekos Corporation Apparatus for treatment of intracranial hemorrhages
US8613714B2 (en) 2010-10-05 2013-12-24 Cerevast Therapeutics, Inc. Non-invasive transcranial ultrasound apparatus
US8603014B2 (en) 2010-10-05 2013-12-10 Cerevast Therapeutics, Inc. Hands-free operator-independent transcranial ultrasound apparatus and methods

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Publication number Publication date
US9808653B2 (en) 2017-11-07
WO2013188084A1 (en) 2013-12-19
JP2015519970A (ja) 2015-07-16
EP2861300A4 (en) 2016-03-16
EP2861300A1 (en) 2015-04-22
US20130338544A1 (en) 2013-12-19
US20180154187A1 (en) 2018-06-07

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