JP6283314B2 - アナグリプチン含有固形製剤 - Google Patents
アナグリプチン含有固形製剤 Download PDFInfo
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- JP6283314B2 JP6283314B2 JP2014538615A JP2014538615A JP6283314B2 JP 6283314 B2 JP6283314 B2 JP 6283314B2 JP 2014538615 A JP2014538615 A JP 2014538615A JP 2014538615 A JP2014538615 A JP 2014538615A JP 6283314 B2 JP6283314 B2 JP 6283314B2
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- anagliptin
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- 239000000901 saccharin and its Na,K and Ca salt Substances 0.000 description 1
- 229940085605 saccharin sodium Drugs 0.000 description 1
- RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 229960004034 sitagliptin Drugs 0.000 description 1
- MFFMDFFZMYYVKS-SECBINFHSA-N sitagliptin Chemical compound C([C@H](CC(=O)N1CC=2N(C(=NN=2)C(F)(F)F)CC1)N)C1=CC(F)=C(F)C=C1F MFFMDFFZMYYVKS-SECBINFHSA-N 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- HEMHJVSKTPXQMS-UHFFFAOYSA-M sodium hydroxide Substances [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 1
- 235000011121 sodium hydroxide Nutrition 0.000 description 1
- 239000012453 solvate Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 235000010356 sorbitol Nutrition 0.000 description 1
- 229960002920 sorbitol Drugs 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 229940032147 starch Drugs 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000006190 sub-lingual tablet Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000005846 sugar alcohols Chemical class 0.000 description 1
- 238000009495 sugar coating Methods 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- WGRQANOPCQRCME-PMACEKPBSA-N teneligliptin Chemical compound O=C([C@H]1NC[C@H](C1)N1CCN(CC1)C1=CC(=NN1C=1C=CC=CC=1)C)N1CCSC1 WGRQANOPCQRCME-PMACEKPBSA-N 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 229960001254 vildagliptin Drugs 0.000 description 1
- 229940100445 wheat starch Drugs 0.000 description 1
- 239000000811 xylitol Substances 0.000 description 1
- 235000010447 xylitol Nutrition 0.000 description 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
- 229960002675 xylitol Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Diabetes (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012214901 | 2012-09-27 | ||
| JP2012214901 | 2012-09-27 | ||
| PCT/JP2013/076205 WO2014051025A1 (fr) | 2012-09-27 | 2013-09-27 | Préparation solide contenant de l'anagliptine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2014051025A1 JPWO2014051025A1 (ja) | 2016-08-22 |
| JP6283314B2 true JP6283314B2 (ja) | 2018-02-21 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014538615A Active JP6283314B2 (ja) | 2012-09-27 | 2013-09-27 | アナグリプチン含有固形製剤 |
Country Status (2)
| Country | Link |
|---|---|
| JP (1) | JP6283314B2 (fr) |
| WO (1) | WO2014051025A1 (fr) |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH10245335A (ja) * | 1997-02-28 | 1998-09-14 | Dainippon Pharmaceut Co Ltd | 圧力に不安定な薬物の打錠方法及びそれに用いられる湿潤顆粒 |
| JPH1121236A (ja) * | 1997-07-01 | 1999-01-26 | Ohara Yakuhin Kogyo Kk | ロキソプロフェン・ナトリウム固形製剤 |
| JP2004250443A (ja) * | 2003-01-31 | 2004-09-09 | Takeda Chem Ind Ltd | 固形製剤 |
| US7345180B2 (en) * | 2003-01-31 | 2008-03-18 | Sanwa Kagaku Kenkyusho Co., Ltd. | Compound inhibiting dipeptidyl peptidase IV |
| EP1852108A1 (fr) * | 2006-05-04 | 2007-11-07 | Boehringer Ingelheim Pharma GmbH & Co.KG | Compositions d'inhibiteurs de la DPP IV |
| AU2009247251B2 (en) * | 2008-05-14 | 2013-07-18 | Sanwa Kagaku Kenkyusho Co., Ltd. | Pharmaceutical preparation comprising DPP-IV inhibitor and other diabetes therapeutic agent in concomitant or combined form |
| AU2010260373A1 (en) * | 2009-06-15 | 2012-01-12 | Merck Sharp & Dohme Corp. | Pharmaceutical compositions of combinations of dipeptidyl peptidase-4 inhibitors with pioglitazone |
| JP2011173796A (ja) * | 2010-02-23 | 2011-09-08 | Nippon Chemiphar Co Ltd | モサプリドクエン酸塩製剤 |
-
2013
- 2013-09-27 WO PCT/JP2013/076205 patent/WO2014051025A1/fr active Application Filing
- 2013-09-27 JP JP2014538615A patent/JP6283314B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JPWO2014051025A1 (ja) | 2016-08-22 |
| WO2014051025A1 (fr) | 2014-04-03 |
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