JP6262206B2 - 医薬組成物 - Google Patents

医薬組成物 Download PDF

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Publication number
JP6262206B2
JP6262206B2 JP2015509430A JP2015509430A JP6262206B2 JP 6262206 B2 JP6262206 B2 JP 6262206B2 JP 2015509430 A JP2015509430 A JP 2015509430A JP 2015509430 A JP2015509430 A JP 2015509430A JP 6262206 B2 JP6262206 B2 JP 6262206B2
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JP
Japan
Prior art keywords
insulin
combination
subject
compound
glu
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2015509430A
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English (en)
Japanese (ja)
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JP2015517458A (ja
JP2015517458A5 (enExample
Inventor
シュー・ヨハンセン
ヘンリエッテ・メルスバッハ
マッズ・アクセルセン
マルティン・ランゲ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
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Novo Nordisk AS
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Publication date
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Publication of JP2015517458A publication Critical patent/JP2015517458A/ja
Publication of JP2015517458A5 publication Critical patent/JP2015517458A5/ja
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP2015509430A 2012-05-01 2013-05-01 医薬組成物 Active JP6262206B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
EP12166251.4 2012-05-01
EP12166251 2012-05-01
EP12166252 2012-05-01
EP12166252.2 2012-05-01
US201261641544P 2012-05-02 2012-05-02
US201261641540P 2012-05-02 2012-05-02
US61/641,540 2012-05-02
US61/641,544 2012-05-02
PCT/EP2013/059073 WO2013164375A1 (en) 2012-05-01 2013-05-01 Pharmaceutical composition

Publications (3)

Publication Number Publication Date
JP2015517458A JP2015517458A (ja) 2015-06-22
JP2015517458A5 JP2015517458A5 (enExample) 2016-06-16
JP6262206B2 true JP6262206B2 (ja) 2018-01-17

Family

ID=49514218

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015509430A Active JP6262206B2 (ja) 2012-05-01 2013-05-01 医薬組成物

Country Status (9)

Country Link
US (1) US9884094B2 (enExample)
EP (1) EP2844274B1 (enExample)
JP (1) JP6262206B2 (enExample)
AU (1) AU2013255880B2 (enExample)
BR (1) BR112014026442A8 (enExample)
CA (1) CA2872083A1 (enExample)
MX (1) MX363119B (enExample)
RU (1) RU2670106C2 (enExample)
WO (1) WO2013164375A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1969004T3 (da) 2005-12-28 2011-11-28 Novo Nordisk As Insulinsammensætninger og metode til at lave en sammensætning
DK2632478T3 (da) 2010-10-27 2019-10-07 Novo Nordisk As Behandling af diabetes melitus under anvendelse af insulinindsprøjtninger indgivet med varierende indsprøjtningsintervaller
EP2976096B1 (en) * 2013-03-20 2019-02-27 Novo Nordisk A/S Insulin dosing regimen
EP2991672A1 (en) * 2013-04-30 2016-03-09 Novo Nordisk A/S Novel administration regime
WO2016001185A1 (en) * 2014-07-02 2016-01-07 Novo Nordisk A/S Dosage regimen for the treatment of diabetes
US10335464B1 (en) 2018-06-26 2019-07-02 Novo Nordisk A/S Device for titrating basal insulin
US12343383B2 (en) 2019-07-12 2025-07-01 Novo Nordisk A/S High concentration insulin formulation
US20250154220A1 (en) * 2023-11-15 2025-05-15 Ambio, Inc. Insulin analogs for the treatment of human metabolic disorder and disease

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH25772A (en) 1985-08-30 1991-10-18 Novo Industri As Insulin analogues, process for their preparation
NZ222907A (en) 1986-12-16 1990-08-28 Novo Industri As Preparation for intranasal administration containing a phospholipid absorption enhancing system
FI913037A7 (fi) 1988-12-23 1991-06-20 Novo Nordisk As Ihmisen insuliinianalogit
IL93282A (en) 1989-02-09 1995-08-31 Lilly Co Eli Insulin analogues
ATE181732T1 (de) 1989-04-19 1999-07-15 Novo Nordisk As Aktive karbonate von polyalkylenoxyden zur modifizierung von polypeptiden
SK282495B6 (sk) 1993-09-17 2002-02-05 Novo Nordisk A/S Acylovaný inzulínový derivát a farmaceutický prostriedok, ktorý ho obsahuje
US5643575A (en) 1993-10-27 1997-07-01 Enzon, Inc. Non-antigenic branched polymer conjugates
US5932462A (en) 1995-01-10 1999-08-03 Shearwater Polymers, Inc. Multiarmed, monofunctional, polymer for coupling to molecules and surfaces
CO4970787A1 (es) * 1997-12-23 2000-11-07 Lilly Co Eli Composiciones insolubles de insulina y derivados de insulina que controlan la glucosa sanguinea
PL2275439T3 (pl) 2003-08-05 2014-09-30 Novo Nordisk As Nowe pochodne insuliny
JP4463814B2 (ja) 2003-08-05 2010-05-19 ノボ ノルディスク アクティーゼルスカブ 新規のインスリン誘導体
DK1969004T3 (da) 2005-12-28 2011-11-28 Novo Nordisk As Insulinsammensætninger og metode til at lave en sammensætning
JP5269767B2 (ja) 2006-05-09 2013-08-21 ノボ・ノルデイスク・エー／エス インスリン誘導体
EP2167032B1 (en) 2007-06-13 2019-08-07 Novo Nordisk A/S Pharmaceutical formulation comprising an insulin derivative
CN102015762B (zh) * 2008-02-19 2015-03-18 百康有限公司 获得纯化的生物活性异源蛋白的方法
WO2010049488A1 (en) * 2008-10-30 2010-05-06 Novo Nordisk A/S Treating diabetes melitus using insulin injections with less than daily injection frequency
EP2632478B1 (en) 2010-10-27 2019-07-24 Novo Nordisk A/S Treating diabetes melitus using insulin injections administered with varying injection intervals

Also Published As

Publication number Publication date
RU2670106C2 (ru) 2018-10-18
JP2015517458A (ja) 2015-06-22
US9884094B2 (en) 2018-02-06
WO2013164375A1 (en) 2013-11-07
EP2844274A1 (en) 2015-03-11
MX363119B (es) 2019-03-11
US20150126439A1 (en) 2015-05-07
MX2014013091A (es) 2014-12-08
BR112014026442A8 (pt) 2018-01-16
RU2014147674A (ru) 2016-06-27
AU2013255880A1 (en) 2014-10-16
BR112014026442A2 (pt) 2017-06-27
CA2872083A1 (en) 2013-11-07
EP2844274B1 (en) 2019-03-20
AU2013255880B2 (en) 2017-07-20

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