JP6234817B2 - シグナル増幅のための方法と試薬 - Google Patents

シグナル増幅のための方法と試薬 Download PDF

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Publication number
JP6234817B2
JP6234817B2 JP2013530331A JP2013530331A JP6234817B2 JP 6234817 B2 JP6234817 B2 JP 6234817B2 JP 2013530331 A JP2013530331 A JP 2013530331A JP 2013530331 A JP2013530331 A JP 2013530331A JP 6234817 B2 JP6234817 B2 JP 6234817B2
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Prior art keywords
dextran
detectable
avidin
cells
binding
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Japanese (ja)
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JP2013539860A (ja
JP2013539860A5 (enExample
Inventor
スティーブン ディー． ミコラジック，
スティーブン ディー． ミコラジック，
リサ エス． ミラー，
リサ エス． ミラー，
Original Assignee
バイオセプト， インコーポレイテッド
バイオセプト， インコーポレイテッド
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Publication of JP2013539860A5 publication Critical patent/JP2013539860A5/ja
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0021—Dextran, i.e. (alpha-1,4)-D-glucan; Derivatives thereof, e.g. Sephadex, i.e. crosslinked dextran
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/02—Dextran; Derivatives thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/548—Carbohydrates, e.g. dextran
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/583—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with non-fluorescent dye label

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
JP2013530331A 2010-09-23 2011-09-22 シグナル増幅のための方法と試薬 Active JP6234817B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38593710P 2010-09-23 2010-09-23
US61/385,937 2010-09-23
PCT/US2011/052837 WO2012040514A2 (en) 2010-09-23 2011-09-22 Methods and reagents for signal amplification

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2015183025A Division JP2015227895A (ja) 2010-09-23 2015-09-16 シグナル増幅のための方法と試薬
JP2017169450A Division JP2017205132A (ja) 2010-09-23 2017-09-04 シグナル増幅のための方法と試薬

Publications (3)

Publication Number Publication Date
JP2013539860A JP2013539860A (ja) 2013-10-28
JP2013539860A5 JP2013539860A5 (enExample) 2014-11-13
JP6234817B2 true JP6234817B2 (ja) 2017-11-22

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Family Applications (3)

Application Number Title Priority Date Filing Date
JP2013530331A Active JP6234817B2 (ja) 2010-09-23 2011-09-22 シグナル増幅のための方法と試薬
JP2015183025A Pending JP2015227895A (ja) 2010-09-23 2015-09-16 シグナル増幅のための方法と試薬
JP2017169450A Withdrawn JP2017205132A (ja) 2010-09-23 2017-09-04 シグナル増幅のための方法と試薬

Family Applications After (2)

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JP2015183025A Pending JP2015227895A (ja) 2010-09-23 2015-09-16 シグナル増幅のための方法と試薬
JP2017169450A Withdrawn JP2017205132A (ja) 2010-09-23 2017-09-04 シグナル増幅のための方法と試薬

Country Status (6)

Country Link
US (1) US9347946B2 (enExample)
EP (1) EP2619588B1 (enExample)
JP (3) JP6234817B2 (enExample)
CN (1) CN103229057B (enExample)
CA (1) CA2812291C (enExample)
WO (1) WO2012040514A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10017678B2 (en) 2012-09-07 2018-07-10 Prestone Products Corporation Heat transfer fluid additive composition

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US10955379B2 (en) 2018-09-27 2021-03-23 Taiwan Semiconductor Manufacturing Co., Ltd. Differential sensing with BioFET sensors
US10984211B1 (en) 2019-10-18 2021-04-20 Taiwan Semiconductor Manufacturing Co., Ltd. Semiconductor device with bioFET and biometric sensors
CN111830250A (zh) * 2020-08-04 2020-10-27 珠海市丽拓生物科技有限公司 一种信号放大的酶标二抗的制备方法

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10017678B2 (en) 2012-09-07 2018-07-10 Prestone Products Corporation Heat transfer fluid additive composition
US10119058B2 (en) 2012-09-07 2018-11-06 Prestone Products Corporation Heat transfer fluid additive composition

Also Published As

Publication number Publication date
EP2619588A2 (en) 2013-07-31
WO2012040514A3 (en) 2012-05-31
WO2012040514A2 (en) 2012-03-29
JP2015227895A (ja) 2015-12-17
CN103229057A (zh) 2013-07-31
CA2812291C (en) 2020-06-16
EP2619588A4 (en) 2014-05-07
JP2017205132A (ja) 2017-11-24
CA2812291A1 (en) 2012-03-29
US20120164661A1 (en) 2012-06-28
CN103229057B (zh) 2016-08-10
US9347946B2 (en) 2016-05-24
JP2013539860A (ja) 2013-10-28
EP2619588B1 (en) 2019-08-07

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