JP6223376B2 - Ｇｉｐ上昇抑制剤の評価又は選択方法 - Google Patents

Ｇｉｐ上昇抑制剤の評価又は選択方法 Download PDF

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Publication number
JP6223376B2
JP6223376B2 JP2015040187A JP2015040187A JP6223376B2 JP 6223376 B2 JP6223376 B2 JP 6223376B2 JP 2015040187 A JP2015040187 A JP 2015040187A JP 2015040187 A JP2015040187 A JP 2015040187A JP 6223376 B2 JP6223376 B2 JP 6223376B2
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fabp4
protein
fabp5
expression level
gene
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JP2015194481A5 (enExample
JP2015194481A (ja
Inventor
義隆 古賀
義隆 古賀
紀子 大崎
紀子 大崎
渡邊　学
学 渡邊
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Kao Corp
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Kao Corp
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Priority to JP2015040187A priority Critical patent/JP6223376B2/ja
Priority to PCT/JP2015/056603 priority patent/WO2015146537A1/ja
Priority to US15/128,666 priority patent/US10132795B2/en
Priority to CN201580015560.7A priority patent/CN106133519B/zh
Priority to EP15769760.8A priority patent/EP3124966B1/en
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5023—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/10—Screening for compounds of potential therapeutic value involving cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2015040187A 2014-03-24 2015-03-02 Ｇｉｐ上昇抑制剤の評価又は選択方法 Expired - Fee Related JP6223376B2 (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2015040187A JP6223376B2 (ja) 2014-03-24 2015-03-02 Ｇｉｐ上昇抑制剤の評価又は選択方法
PCT/JP2015/056603 WO2015146537A1 (ja) 2014-03-24 2015-03-06 Ｇｉｐ上昇抑制剤の評価又は選択方法
US15/128,666 US10132795B2 (en) 2014-03-24 2015-03-06 Method for evaluating or selecting agent for suppressing GIP level elevation
CN201580015560.7A CN106133519B (zh) 2014-03-24 2015-03-06 Gip上升抑制剂的评价或选择方法
EP15769760.8A EP3124966B1 (en) 2014-03-24 2015-03-06 Method for evaluating or selecting agent for suppressing gip level elevation

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2014060341 2014-03-24
JP2014060341 2014-03-24
JP2015040187A JP6223376B2 (ja) 2014-03-24 2015-03-02 Ｇｉｐ上昇抑制剤の評価又は選択方法

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JP2017144146A Division JP6514282B2 (ja) 2014-03-24 2017-07-26 Ｇｉｐ上昇抑制剤の評価又は選択方法

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JP2015194481A JP2015194481A (ja) 2015-11-05
JP2015194481A5 JP2015194481A5 (enExample) 2017-04-06
JP6223376B2 true JP6223376B2 (ja) 2017-11-01

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US (1) US10132795B2 (enExample)
EP (1) EP3124966B1 (enExample)
JP (1) JP6223376B2 (enExample)
CN (1) CN106133519B (enExample)
WO (1) WO2015146537A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6677455B2 (ja) * 2015-05-14 2020-04-08 花王株式会社 毛成長抑制剤の評価又は選択方法
CN114981446A (zh) * 2020-01-17 2022-08-30 日本乐敦制药株式会社 组织形态、组织功能控制剂的评价/筛选方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5518798A (en) 1996-12-03 1998-06-29 Trustees Of Boston University Specific antagonists for glucose-dependent insulinotropic polypeptide (gip)
US7358254B2 (en) 2001-07-13 2008-04-15 Bristol-Myers Squibb Company Method for treating atherosclerosis employing an aP2 inhibitor and combination
DE69939481D1 (de) * 1998-09-17 2008-10-16 Bristol Myers Squibb Co Methode zur behandlung von diabetes die einen ap2-inhibitor und dazugehörige kombinationen verwendet
US6831102B2 (en) * 2001-12-07 2004-12-14 Bristol-Myers Squibb Company Phenyl naphthol ligands for thyroid hormone receptor
JP2004065194A (ja) * 2002-08-09 2004-03-04 Sumitomo Chem Co Ltd 脂肪細胞関連因子の分析方法
EP2898898B1 (en) 2009-03-05 2025-09-10 President and Fellows of Harvard College Secreted AP2 and methods of inhibiting same
WO2011007864A1 (ja) * 2009-07-16 2011-01-20 花王株式会社 血中ｇｉｐ濃度上昇抑制剤
JP5317919B2 (ja) 2009-10-05 2013-10-16 花王株式会社 Ｇｉｐ上昇抑制剤の評価又は選択方法
JP5328595B2 (ja) 2009-10-05 2013-10-30 花王株式会社 Ｇｉｐ上昇抑制剤の評価又は選択方法
WO2012096108A1 (ja) * 2011-01-12 2012-07-19 花王株式会社 血中ｇｉｐ濃度上昇抑制剤、血中インスリン濃度上昇抑制剤、食後血中トリグリセリド濃度低減剤、及び血糖濃度上昇抑制剤
JP6026723B2 (ja) 2011-02-22 2016-11-16 花王株式会社 Ｇｉｐ上昇抑制剤
JP2012171914A (ja) 2011-02-22 2012-09-10 Kao Corp Ｇｉｐ上昇抑制剤
CN102961388A (zh) * 2011-08-30 2013-03-13 三和淀粉工业株式会社 促进glp-1的分泌并且抑制gip的分泌的药剂

Also Published As

Publication number Publication date
EP3124966B1 (en) 2020-04-29
EP3124966A1 (en) 2017-02-01
US10132795B2 (en) 2018-11-20
WO2015146537A1 (ja) 2015-10-01
EP3124966A4 (en) 2017-09-27
US20170227526A1 (en) 2017-08-10
JP2015194481A (ja) 2015-11-05
CN106133519A (zh) 2016-11-16
CN106133519B (zh) 2018-01-09

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