JP6215238B2 - Ｎ−エチル−ｎ−フェニル−１，２−ジヒドロ−４，５−ジ−ヒドロキシ−１−メチル−２−オキソ−３−キノリンカルボキサミド、その製剤、および使用 - Google Patents
Ｎ−エチル−ｎ−フェニル−１，２−ジヒドロ−４，５−ジ−ヒドロキシ−１−メチル−２−オキソ−３−キノリンカルボキサミド、その製剤、および使用 Download PDFInfo
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- JP6215238B2 JP6215238B2 JP2014557840A JP2014557840A JP6215238B2 JP 6215238 B2 JP6215238 B2 JP 6215238B2 JP 2014557840 A JP2014557840 A JP 2014557840A JP 2014557840 A JP2014557840 A JP 2014557840A JP 6215238 B2 JP6215238 B2 JP 6215238B2
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- Prior art keywords
- laquinimod
- pharmaceutical composition
- ethyl
- methyl
- oxo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- GKWPCEFFIHSJOE-UHFFFAOYSA-N laquinimod Chemical compound OC=1C2=C(Cl)C=CC=C2N(C)C(=O)C=1C(=O)N(CC)C1=CC=CC=C1 GKWPCEFFIHSJOE-UHFFFAOYSA-N 0.000 claims description 165
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261599680P | 2012-02-16 | 2012-02-16 | |
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| EP2766020A4 (en) | 2011-10-12 | 2015-04-01 | Teva Pharma | TREATMENT OF MULTIPLE SCLEROSIS BY COMBINING LAQUINIMOD AND FINGOLIMOD |
| CN106063787A (zh) | 2012-02-03 | 2016-11-02 | 泰华制药工业有限公司 | 拉喹莫德用于治疗一线抗TNFα疗法失败的克罗恩氏病患者的用途 |
| TW201400117A (zh) | 2012-06-05 | 2014-01-01 | Teva Pharma | 使用拉喹莫德治療眼發炎疾病 |
| TW201410244A (zh) | 2012-08-13 | 2014-03-16 | Teva Pharma | 用於治療ｇａｂａ媒介之疾病之拉喹莫德（ｌａｑｕｉｎｉｍｏｄ） |
| BR112015010193A2 (pt) | 2012-11-07 | 2017-07-11 | Teva Pharma | sais de amina de laquinimod |
| MX2015011627A (es) | 2013-03-14 | 2016-05-16 | Teva Pharma | Cristales de laquinimod sodico y proceso mejorado para la elaboracion de los mismos. |
| SG11201608674UA (en) | 2014-04-29 | 2016-11-29 | Teva Pharma | Laquinimod for the treatment of relapsing-remitting multiple sclerosis (rrms) patients with a high disability status |
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| TW201339137A (zh) | 2013-10-01 |
| CA2863409A1 (en) | 2013-08-22 |
| ZA201406492B (en) | 2015-12-23 |
| BR112014020372A8 (pt) | 2018-01-23 |
| US20130217724A1 (en) | 2013-08-22 |
| EP3225617A1 (en) | 2017-10-04 |
| US20160151345A1 (en) | 2016-06-02 |
| US9284276B2 (en) | 2016-03-15 |
| CN104114172A (zh) | 2014-10-22 |
| JP2015509941A (ja) | 2015-04-02 |
| AU2013221304B2 (en) | 2017-12-21 |
| HK1198296A1 (en) | 2015-03-27 |
| AU2013221304A1 (en) | 2014-10-02 |
| EP2744498A4 (en) | 2014-12-03 |
| US20170065576A1 (en) | 2017-03-09 |
| JP2018008965A (ja) | 2018-01-18 |
| WO2013123419A1 (en) | 2013-08-22 |
| MX2014009889A (es) | 2014-11-13 |
| AR090073A1 (es) | 2014-10-15 |
| EA201491517A1 (ru) | 2015-03-31 |
| EP2744498A1 (en) | 2014-06-25 |
| US20160151346A1 (en) | 2016-06-02 |
| SG11201404419WA (en) | 2014-10-30 |
| IL233556A0 (en) | 2014-08-31 |
| KR20140138725A (ko) | 2014-12-04 |
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