JP6211513B2 - 自己免疫疾患の治療のための組成物及び方法 - Google Patents

自己免疫疾患の治療のための組成物及び方法 Download PDF

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JP6211513B2
JP6211513B2 JP2014508569A JP2014508569A JP6211513B2 JP 6211513 B2 JP6211513 B2 JP 6211513B2 JP 2014508569 A JP2014508569 A JP 2014508569A JP 2014508569 A JP2014508569 A JP 2014508569A JP 6211513 B2 JP6211513 B2 JP 6211513B2
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interferon
antibody
patient
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JP2014519487A5 (OSRAM
JP2014519487A (ja
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アリッサ， エム． モリモト，
アリッサ， エム． モリモト，
ジャックリーン マックブライド，
ジャックリーン マックブライド，
リチャード ボアメニュー，
リチャード ボアメニュー，
ヨルン ドラッパ，
ヨルン ドラッパ，
ロメオ マシューカ，
ロメオ マシューカ，
ウィリアム， ディー． ケネディ，
ウィリアム， ディー． ケネディ，
マイケル， ジェー． タウンゼンド，
マイケル， ジェー． タウンゼンド，
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Genentech Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/249—Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G01N33/686—Anti-idiotype
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

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  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
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  • Cardiology (AREA)
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JP2014508569A 2011-04-26 2012-04-26 自己免疫疾患の治療のための組成物及び方法 Expired - Fee Related JP6211513B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161479314P 2011-04-26 2011-04-26
US61/479,314 2011-04-26
US201161582179P 2011-12-30 2011-12-30
US61/582,179 2011-12-30
PCT/US2012/035313 WO2012149228A1 (en) 2011-04-26 2012-04-26 Compositions and method for treating autoimmune diseases

Publications (3)

Publication Number Publication Date
JP2014519487A JP2014519487A (ja) 2014-08-14
JP2014519487A5 JP2014519487A5 (OSRAM) 2015-06-18
JP6211513B2 true JP6211513B2 (ja) 2017-10-11

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JP2014508569A Expired - Fee Related JP6211513B2 (ja) 2011-04-26 2012-04-26 自己免疫疾患の治療のための組成物及び方法

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Country Link
US (1) US20140056889A1 (OSRAM)
EP (1) EP2701742A4 (OSRAM)
JP (1) JP6211513B2 (OSRAM)
KR (1) KR20140048877A (OSRAM)
AR (1) AR086074A1 (OSRAM)
AU (1) AU2012249601A1 (OSRAM)
CA (1) CA2834203A1 (OSRAM)
WO (1) WO2012149228A1 (OSRAM)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106086175B (zh) 2006-04-24 2020-03-03 健泰科生物技术公司 用于检测自身免疫性病症的方法和组合物
RU2013157177A (ru) * 2011-05-25 2015-06-27 МЕДИММЬЮН, ЭлЭлСи Способы лечения системной красной волчанки, склеродермии и миозита
WO2013101771A2 (en) * 2011-12-30 2013-07-04 Genentech, Inc. Compositions and method for treating autoimmune diseases
WO2013166408A1 (en) 2012-05-03 2013-11-07 Kala Pharmaceuticals, Inc. Pharmaceutical nanoparticles showing improved mucosal transport
US9827191B2 (en) 2012-05-03 2017-11-28 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
US11596599B2 (en) 2012-05-03 2023-03-07 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
JP6360039B2 (ja) 2012-05-03 2018-07-18 カラ ファーマシューティカルズ インコーポレイテッド 複数の被覆された粒子を含む組成物、医薬組成物、医薬製剤、及び当該粒子の形成方法
HK1217092A1 (zh) 2013-02-15 2016-12-23 Kala Pharmaceuticals, Inc. 治疗性化合物及其用途
US9688688B2 (en) 2013-02-20 2017-06-27 Kala Pharmaceuticals, Inc. Crystalline forms of 4-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinazolin-7-yl)oxy)-1-(2-oxa-7-azaspiro[3.5]nonan-7-yl)butan-1-one and uses thereof
US9353123B2 (en) 2013-02-20 2016-05-31 Kala Pharmaceuticals, Inc. Therapeutic compounds and uses thereof
NZ719185A (en) 2013-11-01 2017-11-24 Kala Pharmaceuticals Inc Crystalline forms of therapeutic compounds and uses thereof
US9890173B2 (en) 2013-11-01 2018-02-13 Kala Pharmaceuticals, Inc. Crystalline forms of therapeutic compounds and uses thereof
GB201501613D0 (en) 2015-01-30 2015-03-18 Ucb Biopharma Sprl Treatment of autoimmune disorders with CD154 antibodies
RU2756109C2 (ru) 2016-03-10 2021-09-28 Виела Байо, Инк. Связывающие ilt7 молекулы и способы их применения
CA3036065A1 (en) 2016-09-08 2018-03-15 Kala Pharmaceuticals, Inc. Crystalline forms of therapeutic compounds and uses thereof
CA3036340A1 (en) 2016-09-08 2018-03-15 Kala Pharmaceuticals, Inc. Crystalline forms of therapeutic compounds and uses thereof
WO2018048747A1 (en) 2016-09-08 2018-03-15 Kala Pharmaceuticals, Inc. Crystalline forms of therapeutic compounds and uses thereof
WO2018136625A2 (en) * 2017-01-20 2018-07-26 Children's Medical Center Corporation Compositions and methods for treating diseases characterized by reactive microglia mediated synapse loss
US12486320B1 (en) * 2018-01-15 2025-12-02 Washington University Compositions and methods for treatment of central nervous system (CNS) autoimmune associated diseases or disorders
US11769592B1 (en) 2018-10-07 2023-09-26 Cerner Innovation, Inc. Classifier apparatus with decision support tool
US11749404B1 (en) * 2018-10-08 2023-09-05 Cerner Innovation, Inc. Decision support tool for venous thromboembolism (VTE)
CN113692287A (zh) * 2018-10-26 2021-11-23 詹森生物科技公司 I型干扰素标记及使用方法
KR102308865B1 (ko) * 2019-02-08 2021-10-05 서울대학교산학협력단 전신 홍반 루푸스 산모의 임신 위험도를 평가하는 방법
JP7494416B2 (ja) * 2019-10-31 2024-06-04 義知 本田 血管老化予測方法、疾患リスク予測方法、血管老化予測用バイオマーカー、疾患用バイオマーカー、測定キット、及び、診断装置
EP4069288A4 (en) * 2019-12-06 2024-01-17 Viela Bio, Inc. TREATMENT METHODS USING ILT7 BINDING PROTEINS
CN114836534A (zh) * 2021-06-08 2022-08-02 中国医学科学院北京协和医院 Samd9l基因突变作为i型干扰素病诊断的标志物及其应用
AU2024266667A1 (en) * 2023-05-02 2025-10-30 4E Therapeutics, Inc. Composition, methods and uses

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US7087726B2 (en) * 2001-02-22 2006-08-08 Genentech, Inc. Anti-interferon-α antibodies
MX2007009466A (es) * 2005-02-10 2007-12-07 Baylor Res Inst Anticuerpos monoclonales de anti-interferon alfa y metodos para su uso.
US9168286B2 (en) * 2005-10-13 2015-10-27 Human Genome Sciences, Inc. Methods and compositions for use in treatment of patients with autoantibody positive disease
CN106086175B (zh) * 2006-04-24 2020-03-03 健泰科生物技术公司 用于检测自身免疫性病症的方法和组合物
RU2527068C2 (ru) * 2006-12-06 2014-08-27 Медиммун, Ллк Фармакодинамические маркеры, индуцированные интерфероном альфа
EP2068924A4 (en) * 2007-05-03 2011-07-20 Medimmune Llc INTERFERON ALPHA INDUCED PHARMACODYNAMIC MARKERS
SG174258A1 (en) * 2009-03-06 2011-10-28 Genentech Inc Antibody formulation
PL2473636T3 (pl) * 2009-09-03 2017-05-31 Medimmune, Llc Diagnostyka interferonu typu 1
WO2013101771A2 (en) * 2011-12-30 2013-07-04 Genentech, Inc. Compositions and method for treating autoimmune diseases

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EP2701742A4 (en) 2015-03-18
CA2834203A1 (en) 2012-11-01
AU2012249601A1 (en) 2013-05-09
AR086074A1 (es) 2013-11-13
KR20140048877A (ko) 2014-04-24
EP2701742A1 (en) 2014-03-05
JP2014519487A (ja) 2014-08-14
US20140056889A1 (en) 2014-02-27
WO2012149228A1 (en) 2012-11-01

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