JP6193275B2 - Ｂ細胞媒介炎症性疾患を治療するための方法 - Google Patents

Ｂ細胞媒介炎症性疾患を治療するための方法 Download PDF

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JP6193275B2
JP6193275B2 JP2014560085A JP2014560085A JP6193275B2 JP 6193275 B2 JP6193275 B2 JP 6193275B2 JP 2014560085 A JP2014560085 A JP 2014560085A JP 2014560085 A JP2014560085 A JP 2014560085A JP 6193275 B2 JP6193275 B2 JP 6193275B2
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seq
antibody
amino acid
cxcl13
acid residues
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JP2015509960A (ja
JP2015509960A5 (cg-RX-API-DMAC7.html
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スミス，アーネスト・エス
ザウダラー，モーリス
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ヴァクシネックス， インコーポレイテッド
ヴァクシネックス， インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Transplantation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2014560085A 2012-03-02 2013-03-01 Ｂ細胞媒介炎症性疾患を治療するための方法 Active JP6193275B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261606049P 2012-03-02 2012-03-02
US61/606,049 2012-03-02
PCT/US2013/028602 WO2013130959A1 (en) 2012-03-02 2013-03-01 Methods for the treatment of b cell-mediated inflammatory diseases

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JP2015509960A JP2015509960A (ja) 2015-04-02
JP2015509960A5 JP2015509960A5 (cg-RX-API-DMAC7.html) 2016-04-21
JP6193275B2 true JP6193275B2 (ja) 2017-09-06

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US (1) US9890213B2 (cg-RX-API-DMAC7.html)
EP (1) EP2820045B1 (cg-RX-API-DMAC7.html)
JP (1) JP6193275B2 (cg-RX-API-DMAC7.html)
KR (1) KR102090969B1 (cg-RX-API-DMAC7.html)
CN (1) CN104520323B (cg-RX-API-DMAC7.html)
AU (1) AU2013225812B2 (cg-RX-API-DMAC7.html)
CA (1) CA2865928C (cg-RX-API-DMAC7.html)
IN (1) IN2014DN08199A (cg-RX-API-DMAC7.html)
NZ (1) NZ629828A (cg-RX-API-DMAC7.html)
WO (1) WO2013130959A1 (cg-RX-API-DMAC7.html)

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EA202092162A1 (ru) * 2018-09-18 2021-07-01 Ай-Маб Биофарма Юэс Лимитед Антитела против cxcl13 для лечения аутоиммунных заболеваний и рака

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Also Published As

Publication number Publication date
EP2820045B1 (en) 2018-08-22
US9890213B2 (en) 2018-02-13
US20150125467A1 (en) 2015-05-07
CN104520323A (zh) 2015-04-15
AU2013225812A1 (en) 2014-09-25
JP2015509960A (ja) 2015-04-02
KR20140138830A (ko) 2014-12-04
CN104520323B (zh) 2018-05-04
IN2014DN08199A (cg-RX-API-DMAC7.html) 2015-05-01
KR102090969B1 (ko) 2020-03-19
EP2820045A1 (en) 2015-01-07
WO2013130959A1 (en) 2013-09-06
AU2013225812B2 (en) 2017-11-30
NZ629828A (en) 2017-05-26
CA2865928A1 (en) 2013-09-06
CA2865928C (en) 2021-02-16

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