JP6180542B2 - 生物試料を調製するためのカートリッジと装置 - Google Patents

生物試料を調製するためのカートリッジと装置 Download PDF

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Publication number
JP6180542B2
JP6180542B2 JP2015547201A JP2015547201A JP6180542B2 JP 6180542 B2 JP6180542 B2 JP 6180542B2 JP 2015547201 A JP2015547201 A JP 2015547201A JP 2015547201 A JP2015547201 A JP 2015547201A JP 6180542 B2 JP6180542 B2 JP 6180542B2
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Japan
Prior art keywords
cartridge
substrate
reaction chamber
fluid
sample
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Expired - Fee Related
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JP2015547201A
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English (en)
Japanese (ja)
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JP2015537229A5 (https=
JP2015537229A (ja
Inventor
ラインホルド ヴィンベルゲル‐フリードル
ラインホルド ヴィンベルゲル‐フリードル
へメルト フレーク ファン
ヘメルト フレーク ファン
デ ストルペ アンヤ ファン
デ ストルペ アンヤ ファン
メンノ ヴィレム ホセ プリンス
メンノ ヴィレム ホセ プリンス
トーレン ヨハンネス アドリアヌス ファン
トーレン ヨハンネス アドリアヌス ファン
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Koninklijke Philips NV
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Koninklijke Philips NV
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Publication of JP2015537229A5 publication Critical patent/JP2015537229A5/ja
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G01N1/312—Apparatus therefor for samples mounted on planar substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/52—Containers specially adapted for storing or dispensing a reagent
    • B01L3/523—Containers specially adapted for storing or dispensing a reagent with means for closing or opening
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/08—Regulating or influencing the flow resistance
    • B01L2400/082—Active control of flow resistance, e.g. flow controllers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
JP2015547201A 2012-12-13 2013-09-24 生物試料を調製するためのカートリッジと装置 Expired - Fee Related JP6180542B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261736697P 2012-12-13 2012-12-13
US61/736,697 2012-12-13
PCT/IB2013/058789 WO2014091321A1 (en) 2012-12-13 2013-09-24 Cartridge and apparatus for preparing a biological sample

Publications (3)

Publication Number Publication Date
JP2015537229A JP2015537229A (ja) 2015-12-24
JP2015537229A5 JP2015537229A5 (https=) 2016-10-27
JP6180542B2 true JP6180542B2 (ja) 2017-08-16

Family

ID=49766135

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015547201A Expired - Fee Related JP6180542B2 (ja) 2012-12-13 2013-09-24 生物試料を調製するためのカートリッジと装置

Country Status (7)

Country Link
US (1) US10393634B2 (https=)
EP (1) EP2931426B1 (https=)
JP (1) JP6180542B2 (https=)
CN (1) CN104837560B (https=)
BR (1) BR112015013512A2 (https=)
RU (1) RU2679226C2 (https=)
WO (1) WO2014091321A1 (https=)

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EP3338096B1 (en) 2015-08-24 2024-03-06 Illumina, Inc. In-line pressure accumulator and flow-control system for biological or chemical assays
US20170158999A1 (en) * 2015-12-03 2017-06-08 The Government Of The United States Of America, As Represented By The Secretary Of The Navy Modular bioreactor for culture of biopaper based tissues
US11460383B2 (en) 2016-06-16 2022-10-04 Nanocytomics, LLC Automated staining system
WO2018067910A1 (en) * 2016-10-06 2018-04-12 Ventana Medical Systems, Inc. System, method and kit for sample preparation
KR101852719B1 (ko) * 2017-04-06 2018-04-27 인제대학교 산학협력단 박막을 이용하여 분리 가능한 구조를 갖는 미세 유체 유속 측정장치
CN107389391B (zh) * 2017-05-11 2024-02-27 武汉康录生物技术股份有限公司 一种自动脱蜡抗原修复系统
EP3401665A1 (en) * 2017-05-12 2018-11-14 University College Dublin National University Of Ireland, Dublin A system and device for analysis of specific matter in liquid samples by optical microscopy
CN107202879B (zh) * 2017-05-18 2018-12-25 杭州依美洛克医学科技有限公司 一种生化实验用加样系统
EP3534139A1 (en) * 2018-03-01 2019-09-04 Koninklijke Philips N.V. Device and method for controlling the volume of a micro chamber arrangement
WO2020106556A1 (en) 2018-11-20 2020-05-28 Xatek, Inc. Dielectric spectroscopy sensing apparaus and method of use
US20250130143A1 (en) * 2020-03-11 2025-04-24 Jin V. WU Devices and components for automated tissue processing and staining and uses thereof
EP4171813A1 (en) 2020-06-26 2023-05-03 Swissmeca SA Microfluidic chip and pumping device
TR202016236A2 (tr) * 2020-10-12 2022-04-21 Aselsan Elektroni̇k Sanayi̇ Ve Ti̇caret Anoni̇m Şi̇rketi̇ Bi̇r mi̇kro-akişkan kartuş
JP7723425B2 (ja) * 2020-11-12 2025-08-14 株式会社GramEye 自動染色物質推定システム
MX2024003202A (es) * 2024-03-13 2025-10-01 Jesus Raul Beltran Ramirez Aparato para te?ir y montar cubreobjetos en laminillas

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US6673620B1 (en) * 1999-04-20 2004-01-06 Cytologix Corporation Fluid exchange in a chamber on a microscope slide
DE60214827T2 (de) 2001-02-12 2007-03-29 Immunivest Corp., Wilmington Kassette als behälter eines probenexemplars für die optische analyse
EP2233564A3 (en) 2002-10-30 2012-11-21 Hitachi, Ltd. Cell culture sheet comprising a functional substrate with a group of columnar micro-pillars and its manufacturing method
US7141386B2 (en) * 2002-10-31 2006-11-28 Hewlett-Packard Development Company, L.P. Cell culture device
US7932098B2 (en) * 2002-10-31 2011-04-26 Hewlett-Packard Development Company, L.P. Microfluidic system utilizing thin-film layers to route fluid
US7854897B2 (en) 2003-05-12 2010-12-21 Yokogawa Electric Corporation Chemical reaction cartridge, its fabrication method, and a chemical reaction cartridge drive system
JP2005037368A (ja) * 2003-05-12 2005-02-10 Yokogawa Electric Corp 化学反応用カートリッジおよびその作製方法および化学反応用カートリッジ駆動システム
US7695676B2 (en) * 2004-08-11 2010-04-13 Hans Kloepfer Methods and apparatus for analyzing an analysis fluid
JP4721414B2 (ja) 2005-08-15 2011-07-13 キヤノン株式会社 反応カートリッジ、反応装置および反応カートリッジの溶液の移動方法
JP4997571B2 (ja) 2006-12-19 2012-08-08 有限会社フルイド マイクロ流体デバイスおよびそれを用いた分析装置
JP2008196943A (ja) * 2007-02-13 2008-08-28 Matsushita Electric Ind Co Ltd 生物学的特異的反応物質の測定チップ、測定システムおよび測定方法
RU2386970C2 (ru) * 2007-06-25 2010-04-20 Закрытое акционерное общество "Молекулярно-медицинские технологии" Биочип с многофункциональной системой идентификации (варианты)
JP5433139B2 (ja) * 2007-06-29 2014-03-05 株式会社東芝 マイクロ化学分析装置、その測定方法、及びマイクロカセット
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Also Published As

Publication number Publication date
CN104837560B (zh) 2017-03-22
JP2015537229A (ja) 2015-12-24
US10393634B2 (en) 2019-08-27
EP2931426B1 (en) 2016-11-23
RU2679226C2 (ru) 2019-02-06
WO2014091321A1 (en) 2014-06-19
CN104837560A (zh) 2015-08-12
RU2015128059A (ru) 2017-01-16
EP2931426A1 (en) 2015-10-21
BR112015013512A2 (pt) 2017-07-11
US20150316454A1 (en) 2015-11-05

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