JP6178241B2 - 血管新生障害の処置 - Google Patents

血管新生障害の処置 Download PDF

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JP6178241B2
JP6178241B2 JP2013553604A JP2013553604A JP6178241B2 JP 6178241 B2 JP6178241 B2 JP 6178241B2 JP 2013553604 A JP2013553604 A JP 2013553604A JP 2013553604 A JP2013553604 A JP 2013553604A JP 6178241 B2 JP6178241 B2 JP 6178241B2
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cells
mir
metastatic
igfbp2
monoclonal antibody
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JP2014507435A5 (fr
JP2014507435A (ja
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ソハイル タヴァズィ
ソハイル タヴァズィ
ニルス ホルバーグ
ニルス ホルバーグ
キム ピーエヌジー
キム ピーエヌジー
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ザ ロックフェラー ユニヴァーシティ
ザ ロックフェラー ユニヴァーシティ
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
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    • A61P27/02—Ophthalmic agents
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1135—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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    • C12N2310/00—Structure or type of the nucleic acid
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JP2013553604A 2011-02-11 2012-02-10 血管新生障害の処置 Active JP6178241B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161441738P 2011-02-11 2011-02-11
US61/441,738 2011-02-11
PCT/US2012/024697 WO2012109567A2 (fr) 2011-02-11 2012-02-10 Traitement de troubles d'angiogenèse

Related Child Applications (1)

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JP2017136730A Division JP6633029B2 (ja) 2011-02-11 2017-07-13 血管新生障害の処置

Publications (3)

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JP2014507435A JP2014507435A (ja) 2014-03-27
JP2014507435A5 JP2014507435A5 (fr) 2015-04-09
JP6178241B2 true JP6178241B2 (ja) 2017-08-09

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JP2013553604A Active JP6178241B2 (ja) 2011-02-11 2012-02-10 血管新生障害の処置
JP2017136730A Active JP6633029B2 (ja) 2011-02-11 2017-07-13 血管新生障害の処置
JP2019223678A Active JP7053559B2 (ja) 2011-02-11 2019-12-11 血管新生障害の処置
JP2022060499A Active JP7536049B2 (ja) 2011-02-11 2022-03-31 血管新生障害の処置

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JP2017136730A Active JP6633029B2 (ja) 2011-02-11 2017-07-13 血管新生障害の処置
JP2019223678A Active JP7053559B2 (ja) 2011-02-11 2019-12-11 血管新生障害の処置
JP2022060499A Active JP7536049B2 (ja) 2011-02-11 2022-03-31 血管新生障害の処置

Country Status (8)

Country Link
US (6) US8980261B2 (fr)
EP (3) EP3301176B1 (fr)
JP (4) JP6178241B2 (fr)
CA (2) CA3146962A1 (fr)
DK (1) DK2673363T3 (fr)
ES (2) ES2645366T3 (fr)
HK (1) HK1245330A1 (fr)
WO (1) WO2012109567A2 (fr)

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Publication number Priority date Publication date Assignee Title
WO2012109567A2 (fr) 2011-02-11 2012-08-16 The Rockefeller University Traitement de troubles d'angiogenèse
TWI465241B (zh) * 2012-12-19 2014-12-21 Ind Tech Res Inst 圓柏（Ｊｕｎｉｐｅｒｕｓ ｃｈｉｎｅｎｓｉｓ）萃取物或木酚素（ｌｉｇｎａｎ）用於製造抑制血管新生之藥物的用途
HUP1300509A2 (hu) * 2013-08-30 2015-03-30 Gabor Firneisz CXCL12 (Chemokine (C-X-C motif) Ligand 12) és IGFBP2 (Insulin-Like Growth Factor Binding Protein 2) gátlók cukorbetegséggel összefüggõ hasnyálmirigyrák kezelésénél történõ alkalmazásra
ES2688737A1 (es) * 2017-05-04 2018-11-06 Universidad Del País Vasco / Euskal Herriko Unibertsitatea Método para diagnosticar placa ateroesclerótica inestable
WO2020079489A2 (fr) * 2018-07-17 2020-04-23 Helixmith Co., Ltd. Traitement d'une neuropathie avec des constructions d'adn codant pour igf-1 et des constructions d'adn codant pour hgf
CN111808938A (zh) * 2019-04-11 2020-10-23 南方医科大学南方医院 Atp6v0d2用于动脉粥样硬化的早期诊断或疗效监控

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EP3301176A1 (fr) 2018-04-04
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JP2022088607A (ja) 2022-06-14
EP3301176B1 (fr) 2019-09-25
CA2841404A1 (fr) 2012-08-16
EP2673363A2 (fr) 2013-12-18
US9493841B2 (en) 2016-11-15
US10301684B2 (en) 2019-05-28
US20210139997A1 (en) 2021-05-13
US20170362664A1 (en) 2017-12-21
US10894989B2 (en) 2021-01-19
US20130323241A1 (en) 2013-12-05
JP6633029B2 (ja) 2020-01-22
US20150292031A1 (en) 2015-10-15
EP2673363A4 (fr) 2015-04-15
HK1245330A1 (zh) 2018-08-24
ES2763087T3 (es) 2020-05-27
EP2673363B1 (fr) 2017-08-23
JP2020054375A (ja) 2020-04-09
JP2018007672A (ja) 2018-01-18
DK2673363T3 (da) 2017-11-13
US20130330333A1 (en) 2013-12-12
US8715660B2 (en) 2014-05-06
US20190352722A1 (en) 2019-11-21
CA3146962A1 (fr) 2012-08-16
US8980261B2 (en) 2015-03-17
WO2012109567A3 (fr) 2012-11-01
JP7053559B2 (ja) 2022-04-12
JP2014507435A (ja) 2014-03-27
EP3604534A1 (fr) 2020-02-05
ES2645366T3 (es) 2017-12-05
JP7536049B2 (ja) 2024-08-19
WO2012109567A2 (fr) 2012-08-16

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