JP6138780B2 - 癌の検出および診断のための抗体ｉ−３８５９の使用 - Google Patents
癌の検出および診断のための抗体ｉ−３８５９の使用 Download PDFInfo
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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- C—CHEMISTRY; METALLURGY
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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Landscapes
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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| PCT/EP2012/064876 WO2013017562A1 (en) | 2011-07-29 | 2012-07-30 | Use of the antibody i-3859 for the detection and diagnosis of cancer |
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| JP2014523920A JP2014523920A (ja) | 2014-09-18 |
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| EP3316159A4 (en) * | 2015-06-25 | 2019-08-14 | Advanced Telecommunications Research Institute International | PREDICTIVE EQUIPMENT BASED ON A SYSTEM ASSOCIATED WITH SEVERAL INSTITUTIONS AND PREDICTION PROGRAM |
| AU2016342355B2 (en) * | 2015-10-23 | 2022-07-28 | Novartis Ag | Computer method and system for deriving cell-to-cell spatial proximities |
| WO2017106332A1 (en) | 2015-12-14 | 2017-06-22 | X4 Pharmaceuticals, Inc. | Methods for treating cancer |
| JP6432962B2 (ja) | 2016-03-29 | 2018-12-05 | 株式会社国際電気通信基礎技術研究所 | 腎機能低下、慢性腎疾患及び腎不全からなる群から選択される少なくとも一種の疾患を予防、又は治療するための有効成分の候補物質のスクリーニング方法 |
| CN114778845A (zh) | 2016-03-29 | 2022-07-22 | 无限生物制药公司 | 药物组合物或食品组合物及评价活性成分体内效果的方法 |
| WO2017177230A1 (en) | 2016-04-08 | 2017-10-12 | X4 Pharmaceuticals, Inc. | Methods for treating cancer |
| IL263834B2 (en) | 2016-06-20 | 2024-01-01 | Kymab Ltd | Anti-pd-l1 antibodies |
| WO2019094392A1 (en) * | 2017-11-07 | 2019-05-16 | X4 Pharmaceuticals, Inc. | Cancer biomarkers and methods of use thereof |
| WO2019200223A1 (en) * | 2018-04-13 | 2019-10-17 | X4 Pharmaceuticals, Inc. | Cancer serum biomarkers and methods of use thereof |
| WO2021183650A1 (en) | 2020-03-10 | 2021-09-16 | X4 Pharmaceuticals, Inc. | Methods for treating neutropenia |
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| JP4786793B2 (ja) * | 1998-03-30 | 2011-10-05 | ノースウエスト バイオセラピューティクス，インコーポレイティド | 腫瘍形成におけるｃｘｃｒ−４遺伝子の役割に基く治療的および診断的応用 |
| ATE265219T1 (de) | 2000-05-09 | 2004-05-15 | Univ British Columbia | Verwendung von cxcr4 antagonisten zur behandlung von krebs und autoimmunkrankheiten |
| EP1290033B1 (en) | 2000-06-05 | 2012-10-31 | The Trustees of Columbia University in the City of New York | Identification and use of human bone marrow-derived endothelial progenitor cells to improve myocardial function after ischemic injury |
| US20030199464A1 (en) | 2002-04-23 | 2003-10-23 | Silviu Itescu | Regeneration of endogenous myocardial tissue by induction of neovascularization |
| US20050002939A1 (en) | 2002-12-23 | 2005-01-06 | Albert Zlotnik | Tumor killing/tumor regression using CXCR4 antagonists |
| AU2003232253A1 (en) * | 2003-05-02 | 2004-11-23 | Polyphor Ag | Template-fixed beta-hairpin peptidomimetics with cxcr4 antagonizing activity |
| US8329178B2 (en) * | 2005-02-18 | 2012-12-11 | Dana-Farber Cancer Institute, Inc. | Antibodies against CXCR4 and methods of use thereof |
| EP1777523A1 (en) * | 2005-10-19 | 2007-04-25 | INSERM (Institut National de la Santé et de la Recherche Médicale) | An in vitro method for the prognosis of progression of a cancer and of the outcome in a patient and means for performing said method |
| RS54424B1 (sr) * | 2006-10-02 | 2016-04-28 | E. R. Squibb & Sons, L.L.C. | Humana antitela koja se vezuju za cxcr4 i njihove upotrebe |
| EP2172485A1 (en) * | 2008-10-01 | 2010-04-07 | Pierre Fabre Medicament | Novel anti CXCR4 antibodies and their use for the treatment of cancer |
| EP2246364A1 (en) * | 2009-04-29 | 2010-11-03 | Pierre Fabre Médicament | Anti CXCR4 antibodies for the treatment of HIV |
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- 2012-07-30 WO PCT/EP2012/064876 patent/WO2013017562A1/en not_active Ceased
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Also Published As
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| WO2013017562A1 (en) | 2013-02-07 |
| RU2636032C2 (ru) | 2017-11-17 |
| MX2014001160A (es) | 2014-07-14 |
| US20140170677A1 (en) | 2014-06-19 |
| BR112014001979A2 (pt) | 2017-02-21 |
| CA2842552A1 (en) | 2013-02-07 |
| AR087363A1 (es) | 2014-03-19 |
| CN103717620A (zh) | 2014-04-09 |
| IL230693A0 (en) | 2014-03-31 |
| EP2736926A1 (en) | 2014-06-04 |
| RU2014103054A (ru) | 2015-09-10 |
| JP2014523920A (ja) | 2014-09-18 |
| KR20140047127A (ko) | 2014-04-21 |
| AU2017204043A1 (en) | 2017-07-06 |
| AU2012292116A1 (en) | 2014-02-06 |
| ZA201400500B (en) | 2014-11-26 |
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