BR112014001979A2 - uso do anticorpo i-3859 para a detecção e diagnóstico de câncer - Google Patents
uso do anticorpo i-3859 para a detecção e diagnóstico de câncerInfo
- Publication number
- BR112014001979A2 BR112014001979A2 BR112014001979A BR112014001979A BR112014001979A2 BR 112014001979 A2 BR112014001979 A2 BR 112014001979A2 BR 112014001979 A BR112014001979 A BR 112014001979A BR 112014001979 A BR112014001979 A BR 112014001979A BR 112014001979 A2 BR112014001979 A2 BR 112014001979A2
- Authority
- BR
- Brazil
- Prior art keywords
- diagnosis
- antibody
- cancer detection
- cancer
- cxcr4
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161513345P | 2011-07-29 | 2011-07-29 | |
| EP11306000 | 2011-07-29 | ||
| PCT/EP2012/064876 WO2013017562A1 (en) | 2011-07-29 | 2012-07-30 | Use of the antibody i-3859 for the detection and diagnosis of cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112014001979A2 true BR112014001979A2 (pt) | 2017-02-21 |
Family
ID=47628653
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112014001979A BR112014001979A2 (pt) | 2011-07-29 | 2012-07-30 | uso do anticorpo i-3859 para a detecção e diagnóstico de câncer |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20140170677A1 (enExample) |
| EP (1) | EP2736926A1 (enExample) |
| JP (1) | JP6138780B2 (enExample) |
| KR (1) | KR20140047127A (enExample) |
| CN (1) | CN103717620A (enExample) |
| AR (1) | AR087363A1 (enExample) |
| AU (2) | AU2012292116A1 (enExample) |
| BR (1) | BR112014001979A2 (enExample) |
| CA (1) | CA2842552A1 (enExample) |
| IL (1) | IL230693A0 (enExample) |
| MX (1) | MX2014001160A (enExample) |
| RU (1) | RU2636032C2 (enExample) |
| WO (1) | WO2013017562A1 (enExample) |
| ZA (1) | ZA201400500B (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3316159A4 (en) | 2015-06-25 | 2019-08-14 | Advanced Telecommunications Research Institute International | PREDICTIVE EQUIPMENT BASED ON A SYSTEM ASSOCIATED WITH SEVERAL INSTITUTIONS AND PREDICTION PROGRAM |
| EP3365682B1 (en) * | 2015-10-23 | 2020-10-07 | Novartis AG | System for deriving cell-to-cell spatial proximities |
| US11357742B2 (en) | 2015-12-14 | 2022-06-14 | X4 Pharmaceuticals, Inc. | Methods for treating cancer |
| CN114594268A (zh) | 2016-03-29 | 2022-06-07 | 无限生物制药公司 | 用以预防或治疗肾脏疾病的活性组分的候选物质的筛选装置和筛选方法 |
| EP3466446B1 (en) | 2016-03-29 | 2023-12-27 | Karydo Therapeutix, Inc. | Pharmaceutical composition or food composition, and method for assessing effect of active ingredient in vivo |
| US11337969B2 (en) | 2016-04-08 | 2022-05-24 | X4 Pharmaceuticals, Inc. | Methods for treating cancer |
| TWI640536B (zh) | 2016-06-20 | 2018-11-11 | 克馬伯有限公司 | 抗體 |
| CN111465613A (zh) * | 2017-11-07 | 2020-07-28 | X4 制药有限公司 | 癌症生物标志物及其使用方法 |
| US20210025895A1 (en) * | 2018-04-13 | 2021-01-28 | X4 Pharmaceuticals, Inc. | Cancer serum biomarkers and methods of use thereof |
| WO2021183650A1 (en) | 2020-03-10 | 2021-09-16 | X4 Pharmaceuticals, Inc. | Methods for treating neutropenia |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU766675B2 (en) * | 1998-03-30 | 2003-10-23 | Northwest Biotherapeutics, Inc. | Therapeutic and diagnostic applications based on the role of the CXCR-4 gene in tumorigenesis |
| JP2003532683A (ja) | 2000-05-09 | 2003-11-05 | ザ ユニバーシティ オブ ブリティッシュ コロンビア | 造血細胞のcxcr4アンタゴニスト治療 |
| AU2001275339A1 (en) | 2000-06-05 | 2001-12-17 | The Trustees Of Columbia University In The City Of New York | Identification and use of human bone marrow-derived endothelial progenitor cells to improve myocardial function after ischemic injury |
| US20030199464A1 (en) | 2002-04-23 | 2003-10-23 | Silviu Itescu | Regeneration of endogenous myocardial tissue by induction of neovascularization |
| US20050002939A1 (en) | 2002-12-23 | 2005-01-06 | Albert Zlotnik | Tumor killing/tumor regression using CXCR4 antagonists |
| AU2003232253A1 (en) * | 2003-05-02 | 2004-11-23 | Polyphor Ag | Template-fixed beta-hairpin peptidomimetics with cxcr4 antagonizing activity |
| US8329178B2 (en) * | 2005-02-18 | 2012-12-11 | Dana-Farber Cancer Institute, Inc. | Antibodies against CXCR4 and methods of use thereof |
| EP1777523A1 (en) * | 2005-10-19 | 2007-04-25 | INSERM (Institut National de la Santé et de la Recherche Médicale) | An in vitro method for the prognosis of progression of a cancer and of the outcome in a patient and means for performing said method |
| EP2486941B1 (en) * | 2006-10-02 | 2017-03-15 | E. R. Squibb & Sons, L.L.C. | Human antibodies that bind CXCR4 and uses thereof |
| EP2172485A1 (en) | 2008-10-01 | 2010-04-07 | Pierre Fabre Medicament | Novel anti CXCR4 antibodies and their use for the treatment of cancer |
| EP2246364A1 (en) * | 2009-04-29 | 2010-11-03 | Pierre Fabre Médicament | Anti CXCR4 antibodies for the treatment of HIV |
-
2012
- 2012-07-27 AR ARP120102745A patent/AR087363A1/es unknown
- 2012-07-30 BR BR112014001979A patent/BR112014001979A2/pt not_active IP Right Cessation
- 2012-07-30 KR KR1020147003605A patent/KR20140047127A/ko not_active Ceased
- 2012-07-30 CA CA2842552A patent/CA2842552A1/en not_active Abandoned
- 2012-07-30 RU RU2014103054A patent/RU2636032C2/ru not_active IP Right Cessation
- 2012-07-30 JP JP2014522119A patent/JP6138780B2/ja not_active Expired - Fee Related
- 2012-07-30 MX MX2014001160A patent/MX2014001160A/es unknown
- 2012-07-30 AU AU2012292116A patent/AU2012292116A1/en not_active Abandoned
- 2012-07-30 WO PCT/EP2012/064876 patent/WO2013017562A1/en not_active Ceased
- 2012-07-30 US US14/235,235 patent/US20140170677A1/en not_active Abandoned
- 2012-07-30 EP EP12740374.9A patent/EP2736926A1/en not_active Ceased
- 2012-07-30 CN CN201280037703.0A patent/CN103717620A/zh active Pending
-
2014
- 2014-01-22 ZA ZA2014/00500A patent/ZA201400500B/en unknown
- 2014-01-28 IL IL230693A patent/IL230693A0/en unknown
-
2017
- 2017-06-15 AU AU2017204043A patent/AU2017204043A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2012292116A1 (en) | 2014-02-06 |
| EP2736926A1 (en) | 2014-06-04 |
| MX2014001160A (es) | 2014-07-14 |
| RU2014103054A (ru) | 2015-09-10 |
| CN103717620A (zh) | 2014-04-09 |
| AR087363A1 (es) | 2014-03-19 |
| CA2842552A1 (en) | 2013-02-07 |
| RU2636032C2 (ru) | 2017-11-17 |
| ZA201400500B (en) | 2014-11-26 |
| AU2017204043A1 (en) | 2017-07-06 |
| JP6138780B2 (ja) | 2017-05-31 |
| WO2013017562A1 (en) | 2013-02-07 |
| JP2014523920A (ja) | 2014-09-18 |
| US20140170677A1 (en) | 2014-06-19 |
| KR20140047127A (ko) | 2014-04-21 |
| IL230693A0 (en) | 2014-03-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A ANUIDADE. |
|
| B08G | Application fees: restoration [chapter 8.7 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2525 DE 28-05-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |