BR112014001979A2 - uso do anticorpo i-3859 para a detecção e diagnóstico de câncer - Google Patents
uso do anticorpo i-3859 para a detecção e diagnóstico de câncerInfo
- Publication number
- BR112014001979A2 BR112014001979A2 BR112014001979A BR112014001979A BR112014001979A2 BR 112014001979 A2 BR112014001979 A2 BR 112014001979A2 BR 112014001979 A BR112014001979 A BR 112014001979A BR 112014001979 A BR112014001979 A BR 112014001979A BR 112014001979 A2 BR112014001979 A2 BR 112014001979A2
- Authority
- BR
- Brazil
- Prior art keywords
- diagnosis
- antibody
- cancer detection
- cancer
- cxcr4
- Prior art date
Links
- 238000003745 diagnosis Methods 0.000 title abstract 4
- 206010028980 Neoplasm Diseases 0.000 title abstract 3
- 201000011510 cancer Diseases 0.000 title abstract 3
- 238000001514 detection method Methods 0.000 title abstract 2
- 101100441540 Xenopus laevis cxcr4-a gene Proteins 0.000 abstract 1
- 101100441541 Xenopus laevis cxcr4-b gene Proteins 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 231100000590 oncogenic Toxicity 0.000 abstract 1
- 230000002246 oncogenic effect Effects 0.000 abstract 1
- 238000004393 prognosis Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161513345P | 2011-07-29 | 2011-07-29 | |
| EP11306000 | 2011-07-29 | ||
| PCT/EP2012/064876 WO2013017562A1 (en) | 2011-07-29 | 2012-07-30 | Use of the antibody i-3859 for the detection and diagnosis of cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112014001979A2 true BR112014001979A2 (pt) | 2017-02-21 |
Family
ID=47628653
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112014001979A BR112014001979A2 (pt) | 2011-07-29 | 2012-07-30 | uso do anticorpo i-3859 para a detecção e diagnóstico de câncer |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20140170677A1 (enExample) |
| EP (1) | EP2736926A1 (enExample) |
| JP (1) | JP6138780B2 (enExample) |
| KR (1) | KR20140047127A (enExample) |
| CN (1) | CN103717620A (enExample) |
| AR (1) | AR087363A1 (enExample) |
| AU (2) | AU2012292116A1 (enExample) |
| BR (1) | BR112014001979A2 (enExample) |
| CA (1) | CA2842552A1 (enExample) |
| IL (1) | IL230693A0 (enExample) |
| MX (1) | MX2014001160A (enExample) |
| RU (1) | RU2636032C2 (enExample) |
| WO (1) | WO2013017562A1 (enExample) |
| ZA (1) | ZA201400500B (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108271422A (zh) * | 2015-06-25 | 2018-07-10 | 株式会社国际电气通信基础技术研究所 | 基于器官间串扰系统的预测装置及预测程序 |
| CN108463727B (zh) * | 2015-10-23 | 2021-06-18 | 诺华股份有限公司 | 用于得到细胞间空间接近度的计算机方法和系统 |
| EP3389652B1 (en) | 2015-12-14 | 2022-09-28 | X4 Pharmaceuticals, Inc. | Methods for treating cancer |
| JP6432962B2 (ja) | 2016-03-29 | 2018-12-05 | 株式会社国際電気通信基礎技術研究所 | 腎機能低下、慢性腎疾患及び腎不全からなる群から選択される少なくとも一種の疾患を予防、又は治療するための有効成分の候補物質のスクリーニング方法 |
| JP6332780B2 (ja) | 2016-03-29 | 2018-05-30 | 株式会社国際電気通信基礎技術研究所 | 医薬組成物又は食品組成物、及び有効成分の体内での効果の評価方法 |
| CA3019394A1 (en) | 2016-04-08 | 2017-10-12 | X4 Pharmaceuticals, Inc. | Methods for treating cancer |
| BR112018076260A2 (pt) | 2016-06-20 | 2019-03-26 | Kymab Limited | anticorpo ou fragmento do mesmo que se liga especificamente a hpd-l1, anticorpo biespecífico ou proteína de fusão, uso de um anticorpo ou fragmento, método, composição farmacêutica, método de modulação, método de inibição, método de tratamento, ácido nucleico, vetor, hospedeiro e imunocitocina |
| US20210349099A1 (en) * | 2017-11-07 | 2021-11-11 | X4 Pharmaceuticals, Inc. | Cancer biomarkers and methods of use thereof |
| CA3095331A1 (en) * | 2018-04-13 | 2019-10-17 | X4 Pharmaceuticals, Inc. | Cancer serum biomarkers and methods of use thereof |
| EP4117662A4 (en) | 2020-03-10 | 2024-04-03 | X4 Pharmaceuticals, Inc. | METHODS OF TREATING NEUTROPENIA |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4786793B2 (ja) * | 1998-03-30 | 2011-10-05 | ノースウエスト バイオセラピューティクス,インコーポレイティド | 腫瘍形成におけるcxcr−4遺伝子の役割に基く治療的および診断的応用 |
| AU5811001A (en) | 2000-05-09 | 2001-11-20 | Univ British Columbia | Cxcr4 antagonist treatment of hematopoietic cells |
| CA2810249A1 (en) | 2000-06-05 | 2001-12-13 | The Trustees Of Columbia University In The City Of New York | Identification and use of human bone marrow-derived endothelial progenitor cell to improve myocardial function after ischemic injury |
| US20030199464A1 (en) | 2002-04-23 | 2003-10-23 | Silviu Itescu | Regeneration of endogenous myocardial tissue by induction of neovascularization |
| US20050002939A1 (en) | 2002-12-23 | 2005-01-06 | Albert Zlotnik | Tumor killing/tumor regression using CXCR4 antagonists |
| WO2004096839A1 (en) * | 2003-05-02 | 2004-11-11 | Polyphor Ag | Template-fixed beta-hairpin peptidomimetics with cxcr4 antagonizing activity |
| EP1871807B1 (en) * | 2005-02-18 | 2012-11-28 | Dana-Farber Cancer Institute, Inc. | Antibodies against cxcr4 and methods of use thereof |
| EP1777523A1 (en) * | 2005-10-19 | 2007-04-25 | INSERM (Institut National de la Santé et de la Recherche Médicale) | An in vitro method for the prognosis of progression of a cancer and of the outcome in a patient and means for performing said method |
| SG178712A1 (en) * | 2006-10-02 | 2012-03-29 | Medarex Inc | Human antibodies that bind cxcr4 and uses thereof |
| EP2172485A1 (en) | 2008-10-01 | 2010-04-07 | Pierre Fabre Medicament | Novel anti CXCR4 antibodies and their use for the treatment of cancer |
| EP2246364A1 (en) | 2009-04-29 | 2010-11-03 | Pierre Fabre Médicament | Anti CXCR4 antibodies for the treatment of HIV |
-
2012
- 2012-07-27 AR ARP120102745A patent/AR087363A1/es unknown
- 2012-07-30 BR BR112014001979A patent/BR112014001979A2/pt not_active IP Right Cessation
- 2012-07-30 JP JP2014522119A patent/JP6138780B2/ja not_active Expired - Fee Related
- 2012-07-30 CN CN201280037703.0A patent/CN103717620A/zh active Pending
- 2012-07-30 CA CA2842552A patent/CA2842552A1/en not_active Abandoned
- 2012-07-30 US US14/235,235 patent/US20140170677A1/en not_active Abandoned
- 2012-07-30 EP EP12740374.9A patent/EP2736926A1/en not_active Ceased
- 2012-07-30 AU AU2012292116A patent/AU2012292116A1/en not_active Abandoned
- 2012-07-30 KR KR1020147003605A patent/KR20140047127A/ko not_active Ceased
- 2012-07-30 WO PCT/EP2012/064876 patent/WO2013017562A1/en not_active Ceased
- 2012-07-30 MX MX2014001160A patent/MX2014001160A/es unknown
- 2012-07-30 RU RU2014103054A patent/RU2636032C2/ru not_active IP Right Cessation
-
2014
- 2014-01-22 ZA ZA2014/00500A patent/ZA201400500B/en unknown
- 2014-01-28 IL IL230693A patent/IL230693A0/en unknown
-
2017
- 2017-06-15 AU AU2017204043A patent/AU2017204043A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013017562A1 (en) | 2013-02-07 |
| IL230693A0 (en) | 2014-03-31 |
| AU2017204043A1 (en) | 2017-07-06 |
| AR087363A1 (es) | 2014-03-19 |
| JP2014523920A (ja) | 2014-09-18 |
| CN103717620A (zh) | 2014-04-09 |
| MX2014001160A (es) | 2014-07-14 |
| JP6138780B2 (ja) | 2017-05-31 |
| RU2636032C2 (ru) | 2017-11-17 |
| ZA201400500B (en) | 2014-11-26 |
| CA2842552A1 (en) | 2013-02-07 |
| AU2012292116A1 (en) | 2014-02-06 |
| EP2736926A1 (en) | 2014-06-04 |
| RU2014103054A (ru) | 2015-09-10 |
| US20140170677A1 (en) | 2014-06-19 |
| KR20140047127A (ko) | 2014-04-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112014001979A2 (pt) | uso do anticorpo i-3859 para a detecção e diagnóstico de câncer | |
| UA113712C2 (xx) | Антитіло до fap і способи його застосування | |
| BR112014002140A2 (pt) | anticorpo anti-cxcr4 e uso do mesmo para a detecção e o diagnóstico de câncer | |
| BR112014026755B8 (pt) | anticorpos contra claudin 18.2 úteis no diagnóstico de câncer | |
| BR112014007382A2 (pt) | anticorpos anti-erbb3 e seus usos | |
| SG10201907215QA (en) | Antibodies Comprising An Ion Concentration Dependent Antigen-Binding Domain, Fc Region Variants, Il-8-Binding Antibodies, And Uses Therof | |
| EA201500219A1 (ru) | Антитело против trop-2 человека, обладающее противоопухолевой активностью in vivo | |
| BR112015007184A2 (pt) | combinação de anticorpos anti-kir e anticorpos anti-pd-1 para tratar câncer | |
| BR112015024553A2 (pt) | anticorpo multiespecífico, anticorpo isolado, ácido nucleico isolado, célula hospedeira, método de produção de anticorpo, imunoconjugado, formulação farmacêutica, uso de anticorpo e método de tratamento de indivíduos com distúrbio | |
| BR112014012590A8 (pt) | Anticorpos anti-cd98 e métodos de uso dos mesmos | |
| BRPI1006134A2 (pt) | anticorpo ou um fragmento funcional do anticorpo, composição farmacêutica, uso de um anticorpo ou um fragmento funcional do mesmo, polinucleotídeo, vetor, e, célula hospedeira transformada. | |
| MX383886B (es) | Anticuerpo anti-trop-2 humano que tiene una actividad antitumoral in vivo. | |
| WO2013033609A3 (en) | Methods and compositions for the treatment and diagnosis of cancer | |
| HK1199100A1 (en) | Methods and compositions for the treatment and diagnosis of colorectal cancer | |
| BR112013008255A2 (pt) | anticorpo isolado ou um fragmento funcional do mesmo, uso de um anticorpo isolado ou de um fragmento funcional do mesmo, composição farmacêutica, polinucleotídeo, vetor, célula transformada, e, método para produzir anticorpo | |
| MX2014015088A (es) | Anticuerpos anti-tofacitinib y usos de los mismos para monitorear farmacos. | |
| UA99339C2 (ru) | Антитело, которое специфично связывает человеческий tyrp1 | |
| WO2012154983A3 (en) | Systems and methods for anti-pax8 antibodies | |
| BR112015021586A2 (pt) | formulações de morfina | |
| WO2015051320A3 (en) | Anti-sox10 antibody systems and methods | |
| MX2011006725A (es) | Combinacion de inhibidores de aurora cinasa y anticuerpos anti-cd20. | |
| HK1205558A1 (en) | Methods and biomarkers for detection and prognosis of cervical cancer | |
| WO2013106747A3 (en) | Methods and compositions for the treatment and diagnosis of thyroid cancer | |
| WO2010031749A9 (en) | Compositions and methods for detecting tlr3 | |
| WO2015013508A3 (en) | Methods for diagnosing and treating immune disease |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A ANUIDADE. |
|
| B08G | Application fees: restoration [chapter 8.7 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2525 DE 28-05-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |